Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q28116976)
Watch
English
Axl is essential for VEGF-A-dependent activation of PI3K/Akt
scientific journal article
In more languages
edit
Statements
instance of
scholarly article
1 reference
stated in
PubMed
PubMed ID
22327215
retrieved
4 January 2017
title
Axl is essential for VEGF-A-dependent activation of PI3K/Akt
(English)
1 reference
stated in
PubMed
PubMed ID
22327215
retrieved
4 January 2017
main subject
AXL receptor tyrosine kinase
1 reference
stated in
GOA release 2020-03-11
protein tyrosine kinase activity
1 reference
stated in
GOA release 2020-03-11
author name string
Guo-Xiang Ruan
series ordinal
1
1 reference
stated in
PubMed
PubMed ID
22327215
retrieved
4 January 2017
Andrius Kazlauskas
series ordinal
2
1 reference
stated in
PubMed
PubMed ID
22327215
retrieved
4 January 2017
language of work or name
English
0 references
publication date
4 April 2012
1 reference
stated in
PubMed
PubMed ID
22327215
retrieved
4 January 2017
published in
The EMBO Journal
1 reference
stated in
PubMed
PubMed ID
22327215
retrieved
4 January 2017
volume
31
1 reference
stated in
PubMed
PubMed ID
22327215
retrieved
4 January 2017
issue
7
1 reference
stated in
PubMed
PubMed ID
22327215
retrieved
4 January 2017
page(s)
1692–1703
1 reference
stated in
PubMed
PubMed ID
22327215
retrieved
4 January 2017
cites work
Intracellular signaling of the Ufo/Axl receptor tyrosine kinase is mediated mainly by a multi-substrate docking-site
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321201
retrieved
20 March 2017
Axl receptor tyrosine kinase stimulated by the vitamin K-dependent protein encoded by growth-arrest-specific gene 6
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321201
retrieved
20 March 2017
Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321201
retrieved
20 March 2017
Different signal transduction properties of KDR and Flt1, two receptors for vascular endothelial growth factor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321201
retrieved
20 March 2017
VEGF receptor-2 Y951 signaling and a role for the adapter molecule TSAd in tumor angiogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321201
retrieved
20 March 2017
Structural basis for autoinhibition of the Ephb2 receptor tyrosine kinase by the unphosphorylated juxtamembrane region
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321201
retrieved
20 March 2017
The biology of VEGF and its receptors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321201
retrieved
20 March 2017
Vascular endothelial growth factor receptor-2: structure, function, intracellular signalling and therapeutic inhibition
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321201
retrieved
20 March 2017
Autophosphorylation of the PDGF receptor in the kinase insert region regulates interactions with cell proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321201
retrieved
20 March 2017
TAM receptors are pleiotropic inhibitors of the innate immune response
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321201
retrieved
20 March 2017
Vascular endothelial growth factor-A is a survival factor for retinal neurons and a critical neuroprotectant during the adaptive response to ischemic injury.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321201
retrieved
20 March 2017
Tyro-3 family receptors are essential regulators of mammalian spermatogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321201
retrieved
20 March 2017
Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321201
retrieved
7 April 2017
Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321201
retrieved
7 April 2017
Tumor angiogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321201
retrieved
7 April 2017
Catalytic specificity of protein-tyrosine kinases is critical for selective signalling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321201
retrieved
7 April 2017
Ranibizumab for neovascular age-related macular degeneration
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321201
retrieved
7 April 2017
VEGF receptor signalling - in control of vascular function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321201
retrieved
7 April 2017
Phospholipase Cgamma activation drives increased production of autotaxin in endothelial cells and lysophosphatidic acid-dependent regression.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321201
retrieved
29 September 2017
VEGF-A: a critical regulator of blood vessel growth
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321201
retrieved
29 September 2017
Axl as a potential therapeutic target in cancer: role of Axl in tumor growth, metastasis and angiogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321201
retrieved
29 September 2017
Role of src-family kinases in hypoxic vasoconstriction of rat pulmonary artery.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321201
retrieved
29 September 2017
The scaffolding adapter Gab1 mediates vascular endothelial growth factor signaling and is required for endothelial cell migration and capillary formation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321201
retrieved
29 September 2017
Ranibizumab versus verteporfin for neovascular age-related macular degeneration.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321201
retrieved
29 September 2017
Isolation and culture of murine heart and lung endothelial cells for in vitro model systems
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321201
retrieved
29 September 2017
Angiogenesis--a new target for future therapy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321201
retrieved
29 September 2017
Chemical rescue of a mutant enzyme in living cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321201
retrieved
29 September 2017
Beyond PTEN mutations: the PI3K pathway as an integrator of multiple inputs during tumorigenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321201
retrieved
29 September 2017
Multiple roles for the receptor tyrosine kinase axl in tumor formation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321201
retrieved
29 September 2017
VEGFR-1 and VEGFR-2: two non-identical twins with a unique physiognomy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321201
retrieved
29 September 2017
Wound-healing assay.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321201
retrieved
29 September 2017
A juxtamembrane tyrosine in the colony stimulating factor-1 receptor regulates ligand-induced Src association, receptor kinase function, and down-regulation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321201
retrieved
29 September 2017
VEGF-receptor signal transduction
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321201
retrieved
29 September 2017
VEGF receptor signal transduction
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321201
retrieved
29 September 2017
The Gas6/Axl system: a novel regulator of vascular cell function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321201
retrieved
29 September 2017
Signalling through the insulin receptor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321201
retrieved
29 September 2017
A role for cadherin-5 in regulation of vascular endothelial growth factor receptor 2 activity in endothelial cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321201
retrieved
29 September 2017
GAS6 mediates adhesion of cells expressing the receptor tyrosine kinase Axl.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321201
retrieved
29 September 2017
A stable human-derived packaging cell line for production of high titer retrovirus/vesicular stomatitis virus G pseudotypes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321201
retrieved
29 September 2017
Platelet-derived growth factor-dependent activation of phosphatidylinositol 3-kinase is regulated by receptor binding of SH2-domain-containing proteins which influence Ras activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321201
retrieved
29 September 2017
Pathological angiogenesis is induced by sustained Akt signaling and inhibited by rapamycin.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321201
retrieved
2 June 2018
Regulating angiogenesis at the level of PtdIns-4,5-P2.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321201
retrieved
2 June 2018
Akt1/protein kinase Balpha is critical for ischemic and VEGF-mediated angiogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321201
retrieved
2 June 2018
Selective requirement for Src kinases during VEGF-induced angiogenesis and vascular permeability
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321201
retrieved
2 June 2018
Association between the PDGF receptor and members of the src family of tyrosine kinases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321201
retrieved
2 June 2018
Synergism between vascular endothelial growth factor and placental growth factor contributes to angiogenesis and plasma extravasation in pathological conditions.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FEMBOJ.2012.21
retrieved
21 January 2018
Inhibition of vascular endothelial growth factor receptor 2-mediated endothelial cell activation by Axl tyrosine kinase receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FEMBOJ.2012.21
retrieved
21 January 2018
R428, a selective small molecule inhibitor of Axl kinase, blocks tumor spread and prolongs survival in models of metastatic breast cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FEMBOJ.2012.21
retrieved
21 January 2018
Src Family Kinases Promote Vessel Stability by Antagonizing the Rho/ROCK Pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FEMBOJ.2012.21
retrieved
21 January 2018
Transcriptional regulation of vascular endothelial cell responses to hypoxia by HIF-1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FEMBOJ.2012.21
retrieved
21 January 2018
The mouse cornea micropocket angiogenesis assay
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FEMBOJ.2012.21
retrieved
21 January 2018
The adaptor protein Gab1 couples the stimulation of vascular endothelial growth factor receptor-2 to the activation of phosphoinositide 3-kinase
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22327215
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Akt signaling mediates VEGF/VPF vascular permeability in vivo
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22327215
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Vascular reactions to histamine, histamine-liberator and leukotaxine in the skin of guinea-pigs
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22327215
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The Adaptor Protein Gab1 Couples the Stimulation of Vascular Endothelial Growth Factor Receptor-2 to the Activation of Phosphoinositide 3-Kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FEMBOJ.2012.21
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/EMBOJ.2012.21
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4702475
OpenCitations bibliographic resource ID
4702475
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4702475
PMCID
3321201
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4702475
PubMed ID
22327215
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4702475
ResearchGate publication ID
221825657
0 references
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit