(Q28117429)

4 January 2017

title

The X11alpha protein slows cellular amyloid precursor protein processing and reduces Abeta40 and Abeta42 secretion (English)

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4 January 2017

The X11α Protein Slows Cellular Amyloid Precursor Protein Processing and Reduces Aβ40 and Aβ42 Secretion (English)

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R. Scott Turner

5

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Jean-Paul Borg

object named as

Jean-Paul Borg

1

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author name string

J. P. Borg

1

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4 January 2017

Y. Yang

2

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4 January 2017

M. De Taddéo-Borg

3

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4 January 2017

B. Margolis

4

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4 January 2017

R. S. Turner

5

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4 January 2017

Yunning Yang

2

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Mylène De Taddéo-Borg

3

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Ben Margolis

4

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language of work or name

English

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publication date

12 June 1998

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Journal of Biological Chemistry

4 January 2017

published in

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4 January 2017

volume

273

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4 January 2017

issue

24

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4 January 2017

page(s)

14761–14766

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The Alzheimer family of diseases: many etiologies, one pathogenesis?

4 January 2017

14761-14766

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cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.24.14761

Amyloid beta-protein and the genetics of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.24.14761

Alzheimer's disease: genotypes, phenotypes, and treatments

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.24.14761

The phosphotyrosine interaction domains of X11 and FE65 bind to distinct sites on the YENPTY motif of amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.24.14761

The regions of the Fe65 protein homologous to the phosphotyrosine interaction/phosphotyrosine binding domain of Shc bind the intracellular domain of the Alzheimer's amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.24.14761

Interaction of the phosphotyrosine interaction/phosphotyrosine binding-related domains of Fe65 with wild-type and mutant Alzheimer's beta-amyloid precursor proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.24.14761

Association of a novel human FE65-like protein with the cytoplasmic domain of the beta-amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.24.14761

The intracellular cytoplasmic domain of the Alzheimer's disease amyloid precursor protein interacts with phosphotyrosine-binding domain proteins in the yeast two-hybrid system

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.24.14761

An alternative to SH2 domains for binding tyrosine-phosphorylated proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.24.14761

Numb-associated kinase interacts with the phosphotyrosine binding domain of Numb and antagonizes the function of Numb in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.24.14761

Control of daughter cell fates during asymmetric division: interaction of Numb and Notch

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.24.14761

Sequence-specific recognition of the internalization motif of the Alzheimer's amyloid precursor protein by the X11 PTB domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.24.14761

Novel beta-secretase cleavage of beta-amyloid precursor protein in the endoplasmic reticulum/intermediate compartment of NT2N cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.24.14761

An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.24.14761

Mutation of the beta-amyloid precursor protein in familial Alzheimer's disease increases beta-protein production

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.24.14761

Release of excess amyloid beta protein from a mutant amyloid beta protein precursor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.24.14761

The Swedish mutation causes early-onset Alzheimer's disease by beta-secretase cleavage within the secretory pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.24.14761

Intracellular accumulation of beta-amyloid in cells expressing the Swedish mutant amyloid precursor protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.24.14761

Missense mutations associated with familial Alzheimer's disease in Sweden lead to the production of the amyloid peptide without internalization of its precursor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.24.14761

Generation of Alzheimer beta-amyloid protein in the trans-Golgi network in the apparent absence of vesicle formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.24.14761

A multivalent PDZ-domain protein assembles signalling complexes in a G-protein-coupled cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.24.14761

The WW domain of neural protein FE65 interacts with proline-rich motifs in Mena, the mammalian homolog of Drosophila enabled

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.24.14761

Generation of beta-amyloid in the secretory pathway in neuronal and nonneuronal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.24.14761

Human neurons derived from a teratocarcinoma cell line express solely the 695-amino acid amyloid precursor protein and produce intracellular beta-amyloid or A4 peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.24.14761

Amyloids beta40 and beta42 are generated intracellularly in cultured human neurons and their secretion increases with maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.24.14761

Intracellular and secreted Alzheimer beta-amyloid species are generated by distinct mechanisms in cultured hippocampal neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.24.14761

Alzheimer's A beta(1-42) is generated in the endoplasmic reticulum/intermediate compartment of NT2N cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.24.14761

Expression and analysis of presenilin 1 in a human neuronal system: localization in cell bodies and dendrites

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.24.14761

Alzheimer-associated presenilins 1 and 2: neuronal expression in brain and localization to intracellular membranes in mammalian cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.24.14761

Endoproteolysis of presenilin 1 and accumulation of processed derivatives in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.24.14761

Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.24.14761

Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.24.14761

Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.24.14761

Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.24.14761

21 January 2018

Identifiers

DOI

10.1074/JBC.273.24.14761

0 references

1 reference