(Q28119180)

4 January 2017

title

Functional characterization of the human dendritic cell immunodeficiency associated with the IRF8(K108E) mutation (English)

1 reference

Interferon regulatory factor 8

4 January 2017

main subject

1 reference

cellular response to interferon-gamma

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

1 reference

Jean-Laurent Casanova

7

0 references

David Langlais

David Langlais

2

0 references

Venetia Bigley

Venetia Bigley

5

0 references

Albert M Berghuis

Albert Berghuis

9

0 references

Guillaume Bourque

4

Guillaume Bourque

1 reference

4 January 2017

1

Sandra Salem

1 reference

4 January 2017

François Lefebvre

3

1 reference

4 January 2017

Muzz Haniffa

6

1 reference

4 January 2017

David Burk

8

1 reference

4 January 2017

Karina M. Butler

10

1 reference

4 January 2017

Timothy Ronan Leahy

11

1 reference

4 January 2017

Sophie Hambleton

12

1 reference

4 January 2017

Philippe Gros

13

1 reference

4 January 2017

language of work or name

English

0 references

publication date

18 September 2014

1 reference

4 January 2017

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4 January 2017

volume

124

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4 January 2017

issue

12

1 reference

4 January 2017

page(s)

1894–1904

1 reference

describes a project that uses

4 January 2017

ImageJ

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4168344/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

20 March 2017

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Mycobacterial disease and impaired IFN-γ immunity in humans with inherited ISG15 deficiency

20 March 2017

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20 March 2017

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Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci

20 March 2017

1 reference

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Structure of IRF-1 with bound DNA reveals determinants of interferon regulation

20 March 2017

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20 March 2017

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20 March 2017

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Ubiquitin-dependent degradation of interferon regulatory factor-8 mediated by Cbl down-regulates interleukin-12 expression

20 March 2017

1 reference

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Synergistic activation of interleukin-12 p35 gene transcription by interferon regulatory factor-1 and interferon consensus sequence-binding protein

20 March 2017

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A mutation in the Icsbp1 gene causes susceptibility to infection and a chronic myeloid leukemia-like syndrome in BXH-2 mice

20 March 2017

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IRF family of transcription factors as regulators of host defense

20 March 2017

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The small ubiquitin-like modifier-deconjugating enzyme sentrin-specific peptidase 1 switches IFN regulatory factor 8 from a repressor to an activator during macrophage activation

20 March 2017

1 reference

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Innate immunity to intraphagosomal pathogens is mediated by interferon regulatory factor 8 (IRF-8) that stimulates the expression of macrophage-specific Nramp1 through antagonizing repression by c-Myc

20 March 2017

1 reference

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Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

20 March 2017

1 reference

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Genetics of rheumatoid arthritis contributes to biology and drug discovery

20 March 2017

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TM4: a free, open-source system for microarray data management and analysis

7 April 2017

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GATA2 deficiency: a protean disorder of hematopoiesis, lymphatics, and immunity.

7 April 2017

1 reference

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Irf8-regulated genomic responses drive pathological inflammation during cerebral malaria

29 September 2017

1 reference

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Genetic variation associated with circulating monocyte count in the eMERGE Network

29 September 2017

1 reference

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29 September 2017

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Dissecting the genetics of complex inheritance: linkage disequilibrium mapping provides insight into Crohn disease

29 September 2017

1 reference

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Association of NCF2, IKZF1, IRF8, IFIH1, and TYK2 with systemic lupus erythematosus

29 September 2017

1 reference

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Exome sequencing identifies GATA-2 mutation as the cause of dendritic cell, monocyte, B and NK lymphoid deficiency.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4168344

IRF8 mutations and human dendritic-cell immunodeficiency

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4168344

Positive regulatory domain I (PRDM1) and IRF8/PU.1 counter-regulate MHC class II transactivator (CIITA) expression during dendritic cell maturation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4168344

IFN regulatory factor 8 restricts the size of the marginal zone and follicular B cell pools

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4168344

The IRF family transcription factors in immunity and oncogenesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4168344

The BXH2 mutation in IRF8 differentially impairs dendritic cell subset development in the mouse

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4168344

Icsbp1/IRF-8 is required for innate and adaptive immune responses against intracellular pathogens

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4168344

Complex formation of the interferon (IFN) consensus sequence-binding protein with IRF-1 is essential for murine macrophage IFN-gamma-induced iNOS gene expression

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4168344

IFN-stimulated gene 15 is synergistically activated through interactions between the myelocyte/lymphocyte-specific transcription factors, PU.1, IFN regulatory factor-8/IFN consensus sequence binding protein, and IFN regulatory factor-4: characteriza

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4168344

Genetic dissection of immunity to mycobacteria: the human model

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4168344

An IFN-gamma-inducible transcription factor, IFN consensus sequence binding protein (ICSBP), stimulates IL-12 p40 expression in macrophages

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4168344

Roles of IFN consensus sequence binding protein and PU.1 in regulating IL-18 gene expression

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4168344

PU.1, interferon regulatory factor 1, and interferon consensus sequence-binding protein cooperate to increase gp91(phox) expression

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4168344

Interferon (IFN) consensus sequence-binding protein, a transcription factor of the IFN regulatory factor family, regulates immune responses in vivo through control of interleukin 12 expression

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4168344

Crucial role of interferon consensus sequence binding protein, but neither of interferon regulatory factor 1 nor of nitric oxide synthesis for protection against murine listeriosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4168344

The human syndrome of dendritic cell, monocyte, B and NK lymphoid deficiency

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4168344

Nramp1-mediated innate resistance to intraphagosomal pathogens is regulated by IRF-8, PU.1, and Miz-1.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4168344

ICSBP directs bipotential myeloid progenitor cells to differentiate into mature macrophages.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4168344

Cutting edge: IFN consensus sequence binding protein/IFN regulatory factor 8 drives the development of type I IFN-producing plasmacytoid dendritic cells

27 November 2018

1 reference

12 December 2020

Immunological conditions of children with BCG disseminated infection

1 reference

12 December 2020

Phosphorylation events modulate the ability of interferon consensus sequence binding protein to interact with interferon regulatory factors and to bind DNA

1 reference

12 December 2020

IFN regulatory factor-4 and -8 govern dendritic cell subset development and their functional diversity

1 reference

12 December 2020

10.1182/BLOOD-2014-04-570879

Identifiers

DOI

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1 reference

1 reference

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