(Q28143337)

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Superactivation of Pax6-mediated transactivation from paired domain-binding sites by dna-independent recruitment of different homeodomain proteins

scientific article (publication date: 9 February 2001)

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scholarly article

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Superactivation of Pax6-mediated transactivation from paired domain-binding sites by dna-independent recruitment of different homeodomain proteins (English)

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Ingvild Mikkola

1

object named as

I Mikkola

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4

object named as

T Johansen

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author name string

J A Bruun

2

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T Holm

3

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language of work or name

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publication date

9 February 2001

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Journal of Biological Chemistry

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276

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6

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4109-18

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Evolution and role of Pax genes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008882200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008882200

21 January 2018

DNA-binding and transactivation properties of Pax-6: three amino acids in the paired domain are responsible for the different sequence recognition of Pax-6 and BSAP (Pax-5).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008882200

21 January 2018

PAX6 gene dosage effect in a family with congenital cataracts, aniridia, anophthalmia and central nervous system defects

1 reference

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21 January 2018

Dissection of the transactivation function of the transcription factor encoded by the eye developmental gene PAX6.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008882200

21 January 2018

PAX-6 in development and evolution

1 reference

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twin of eyeless, a second Pax-6 gene of Drosophila, acts upstream of eyeless in the control of eye development

1 reference

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21 January 2018

Induction of ectopic eyes by targeted expression of the eyeless gene in Drosophila

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21 January 2018

Zebrafish contains two pax6 genes involved in eye development

1 reference

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21 January 2018

Genomic structure, evolutionary conservation and aniridia mutations in the human PAX6 gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008882200

21 January 2018

Mutations at the PAX6 locus are found in heterogeneous anterior segment malformations including Peters' anomaly

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008882200

21 January 2018

Defects of neuronal migration and the pathogenesis of cortical malformations are associated with Small eye (Sey) in the mouse, a point mutation at the Pax-6-locus.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008882200

21 January 2018

Mutations in the homeobox gene HESX1/Hesx1 associated with septo-optic dysplasia in human and mouse

1 reference

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21 January 2018

rax, a novel paired-type homeobox gene, shows expression in the anterior neural fold and developing retina

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21 January 2018

The Rx homeobox gene is essential for vertebrate eye development

1 reference

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Xrx1, a novel Xenopus homeobox gene expressed during eye and pineal gland development.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008882200

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Two independent and interactive DNA-binding subdomains of the Pax6 paired domain are regulated by alternative splicing

1 reference

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21 January 2018

Characterization of quail Pax-6 (Pax-QNR) proteins expressed in the neuroretina

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Alternative splicing of Pax6 in bovine eye and evolutionary conservation of intron sequences

1 reference

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Specification of sense-organ identity by a Caenorhabditis elegans Pax-6 homologue

1 reference

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21 January 2018

High resolution crystal structure of a paired (Pax) class cooperative homeodomain dimer on DNA

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008882200

21 January 2018

Cooperative dimerization of paired class homeo domains on DNA.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008882200

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Determination of the nuclear magnetic resonance solution structure of an Antennapedia homeodomain-DNA complex

1 reference

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Crystal structure of an engrailed homeodomain-DNA complex at 2.8 A resolution: a framework for understanding homeodomain-DNA interactions

1 reference

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21 January 2018

Crystal structure of a MAT alpha 2 homeodomain-operator complex suggests a general model for homeodomain-DNA interactions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008882200

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Identification of BSAP (Pax-5) target genes in early B-cell development by loss- and gain-of-function experiments

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008882200

21 January 2018

BSAP can repress enhancer activity by targeting PU.1 function

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008882200

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Interaction of the pRB-family proteins with factors containing paired-like homeodomains

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008882200

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Human and Drosophila homeodomain proteins that enhance the DNA-binding activity of serum response factor

1 reference

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21 January 2018

Developmental expression of a novel murine homeobox gene (Chx10): evidence for roles in determination of the neuroretina and inner nuclear layer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008882200

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En-1 and En-2, two mouse genes with sequence homology to the Drosophila engrailed gene: expression during embryogenesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008882200

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Conservation of the expression and function of apterous orthologs in Drosophila and mammals

1 reference

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Prep1, a novel functional partner of Pbx proteins.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008882200

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Structure and chromosomal localization of the human homeobox gene Prox 1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008882200

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The human HOX gene family

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008882200

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Rb binds c-Jun and activates transcription

1 reference

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21 January 2018

Regulatory gene expression boundaries demarcate sites of neuronal differentiation in the embryonic zebrafish forebrain

1 reference

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21 January 2018

The paired domain-containing nuclear factor pax[b] is expressed in specific commissural interneurons in zebrafish embryos

1 reference

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A single amino acid exchange transfers VP16-induced positive control from the Oct-1 to the Oct-2 homeo domain

1 reference

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MRG1 binds to the LIM domain of Lhx2 and may function as a coactivator to stimulate glycoprotein hormone alpha-subunit gene expression

1 reference

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Functional dissection of a transcriptionally active, target-specific Hox-Pbx complex

1 reference

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The mammalian Cut homeodomain protein functions as a cell-cycle-dependent transcriptional repressor which downmodulates p21WAF1/CIP1/SDI1 in S phase

1 reference

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HOX11 interacts with protein phosphatases PP2A and PP1 and disrupts a G2/M cell-cycle checkpoint

1 reference

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21 January 2018

Homeodomain-interacting protein kinases, a novel family of co-repressors for homeodomain transcription factors

1 reference

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21 January 2018

The cardiac tissue-restricted homeobox protein Csx/Nkx2.5 physically associates with the zinc finger protein GATA4 and cooperatively activates atrial natriuretic factor gene expression

1 reference

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Extra specificity from extradenticle: the partnership between HOX and PBX/EXD homeodomain proteins

1 reference

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The transcriptional repressor even-skipped interacts directly with TATA-binding protein

1 reference

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21 January 2018

Homeodomain interaction with the beta subunit of the general transcription factor TFIIE.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008882200

21 January 2018

Recruitment of the tinman homolog Nkx-2.5 by serum response factor activates cardiac alpha-actin gene transcription

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008882200

21 January 2018

The RAG1 homeodomain recruits HMG1 and HMG2 to facilitate recombination signal sequence binding and to enhance the intrinsic DNA-bending activity of RAG1-RAG2

1 reference

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21 January 2018

Smad1 domains interacting with Hoxc-8 induce osteoblast differentiation

1 reference

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POU-domain proteins Pit-1 and Oct-1 interact to form a heteromeric complex and can cooperate to induce expression of the prolactin promoter

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008882200

21 January 2018

Conformational changes induced in Hoxb-8/Pbx-1 heterodimers in solution and upon interaction with specific DNA

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008882200

21 January 2018

The novel homeoprotein Prep1 modulates Pbx-Hox protein cooperativity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008882200

21 January 2018

Developmental effects of ectopic expression of the glucocorticoid receptor DNA binding domain are alleviated by an amino acid substitution that interferes with homeodomain binding

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008882200

21 January 2018

Helix 2 of the paired domain plays a key role in the regulation of DNA-binding by the Pax-3 homeodomain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008882200

21 January 2018

Analysis of the mouse Splotch-delayed mutation indicates that the Pax-3 paired domain can influence homeodomain DNA-binding activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008882200

21 January 2018

Modulation of PAX6 homeodomain function by the paired domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008882200

21 January 2018

Protein and DNA contact surfaces that mediate the selective action of the Phox1 homeodomain at the c-fos serum response element

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008882200

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The Pax3-FKHR oncoprotein is unresponsive to the Pax3-associated repressor hDaxx

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008882200

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HIRA, a mammalian homologue of Saccharomyces cerevisiae transcriptional co-repressors, interacts with Pax3

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008882200

21 January 2018

Pax-6 and Cdx-2/3 interact to activate glucagon gene expression on the G1 control element

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008882200

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AML1 (CBFalpha2) cooperates with B cell-specific activating protein (BSAP/PAX5) in activation of the B cell-specific BLK gene promoter

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008882200

21 January 2018

Pax-3 contains domains for transcription activation and transcription inhibition

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008882200

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Dual roles for Pax-6: a transcriptional repressor of lens fiber cell-specific beta-crystallin genes.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008882200

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Dependence of BSAP repressor and activator functions on BSAP concentration

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008882200

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Phosphorylation of the Transactivation Domain of Pax6 by Extracellular Signal-regulated Kinase and p38 Mitogen-activated Protein Kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008882200

21 January 2018

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10.1074/JBC.M008882200

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release_qk6gu6uyqnaopgeoo4cqakj3me

1 reference

https://api.fatcat.wiki/v0/release/qk6gu6uyqnaopgeoo4cqakj3me

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