(Q28184828)

English

Reconstitution of sterol-regulated endoplasmic reticulum-to-Golgi transport of SREBP-2 in insect cells by co-expression of mammalian SCAP and Insigs

scientific article (publication date: 12 September 2003)

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scholarly article

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Reconstitution of sterol-regulated endoplasmic reticulum-to-Golgi transport of SREBP-2 in insect cells by co-expression of mammalian SCAP and Insigs (English)

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endoplasmic reticulum

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Joseph L. Goldstein

2

object named as

Joseph L Goldstein

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author name string

Irina Y Dobrosotskaya

1

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Michael S Brown

3

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Robert B Rawson

4

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language of work or name

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publication date

12 September 2003

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Journal of Biological Chemistry

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278

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37

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35837-43

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The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306476200

21 January 2018

Mutant mammalian cells as tools to delineate the sterol regulatory element-binding protein pathway for feedback regulation of lipid synthesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306476200

21 January 2018

Crucial step in cholesterol homeostasis: sterols promote binding of SCAP to INSIG-1, a membrane protein that facilitates retention of SREBPs in ER

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306476200

21 January 2018

Insig-2, a second endoplasmic reticulum protein that binds SCAP and blocks export of sterol regulatory element-binding proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306476200

21 January 2018

Sterol resistance in CHO cells traced to point mutation in SREBP cleavage-activating protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306476200

21 January 2018

Sterols regulate processing of carbohydrate chains of wild-type SREBP cleavage-activating protein (SCAP), but not sterol-resistant mutants Y298C or D443N.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306476200

21 January 2018

Three mutations in sterol-sensing domain of SCAP block interaction with insig and render SREBP cleavage insensitive to sterols.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306476200

21 January 2018

The SREBP pathway in Drosophila: regulation by palmitate, not sterols

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306476200

21 January 2018

Regulation of SREBP processing and membrane lipid production by phospholipids in Drosophila

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306476200

21 January 2018

Identification of complexes between the COOH-terminal domains of sterol regulatory element-binding proteins (SREBPs) and SREBP cleavage-activating protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306476200

21 January 2018

Regulated cleavage of sterol regulatory element binding proteins requires sequences on both sides of the endoplasmic reticulum membrane

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306476200

21 January 2018

Cleavage of sterol regulatory element-binding proteins (SREBPs) at site-1 requires interaction with SREBP cleavage-activating protein. Evidence from in vivo competition studies

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306476200

21 January 2018

Unsaturated fatty acids down-regulate srebp isoforms 1a and 1c by two mechanisms in HEK-293 cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306476200

21 January 2018

Cleavage site for sterol-regulated protease localized to a leu-Ser bond in the lumenal loop of sterol regulatory element-binding protein-2.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306476200

21 January 2018

SREBP-1, a membrane-bound transcription factor released by sterol-regulated proteolysis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306476200

21 January 2018

Sterols block binding of COPII proteins to SCAP, thereby controlling SCAP sorting in ER

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306476200

21 January 2018

ER export: public transportation by the COPII coach

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306476200

21 January 2018

SREBP cleavage-activating protein (SCAP) is required for increased lipid synthesis in liver induced by cholesterol deprivation and insulin elevation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306476200

21 January 2018

Cholesterol addition to ER membranes alters conformation of SCAP, the SREBP escort protein that regulates cholesterol metabolism

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306476200

21 January 2018

Signal transduction of stress via ceramide

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306476200

21 January 2018

SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M306476200

Identifiers

10.1074/JBC.M306476200

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release_k4iv7bjeujc47pdwpkqh56nt2a

1 reference

https://api.fatcat.wiki/v0/release/k4iv7bjeujc47pdwpkqh56nt2a

24 November 2022

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