(Q28204964)

1

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Jyoti C Jonnalagadda

2

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Magtouf H Gatei

3

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Herman H W Sillje

4

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Bin-Bing Zhou

5

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Kumkum Khanna

Activation of mammalian Chk1 during DNA replication arrest: a role for Chk1 in the intra-S phase checkpoint monitoring replication origin firing

7

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language of work or name

English

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publication date

4 September 2003

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published in

Oncogene

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volume

22

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issue

38

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page(s)

5927-37

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cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206691

Ataxia telangiectasia mutated (ATM) kinase and ATM and Rad3 related kinase mediate phosphorylation of Brca1 at distinct and overlapping sites. In vivo assessment using phospho-specific antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206691

The Chk1 protein kinase and the Cdc25C regulatory pathways are targets of the anticancer agent UCN-01

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206691

Determination of substrate motifs for human Chk1 and hCds1/Chk2 by the oriented peptide library approach.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206691

Radiosensitivity in ataxia-telangiectasia: a new explanation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206691

Caffeine abolishes the mammalian G(2)/M DNA damage checkpoint by inhibiting ataxia-telangiectasia-mutated kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206691

DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206691

7 January 2021

Defect in multiple cell cycle checkpoints in ataxia-telangiectasia postirradiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206691

7 January 2021

Replication checkpoint enforced by kinases Cds1 and Chk1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206691

7 January 2021

Basis for the checkpoint signal specificity that regulates Chk1 and Cds1 protein kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206691

7 January 2021

A system for stable expression of short interfering RNAs in mammalian cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206691

7 January 2021

Chk2 activation dependence on Nbs1 after DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206691

7 January 2021

Replication checkpoint: preventing mitotic catastrophe

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206691

7 January 2021

Overexpression of a kinase-inactive ATR protein causes sensitivity to DNA-damaging agents and defects in cell cycle checkpoints

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206691

7 January 2021

The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206691

7 January 2021

Solubilization and purification of enzymatically active glutathione S-transferase (pGEX) fusion proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206691

7 January 2021

ATM-dependent phosphorylation of nibrin in response to radiation exposure

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206691

7 January 2021

Xenopus ATR is a replication-dependent chromatin-binding protein required for the DNA replication checkpoint

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206691

7 January 2021

Cell cycle checkpoints and DNA repair preserve the stability of the human genome

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206691

7 January 2021

ATM associates with and phosphorylates p53: mapping the region of interaction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206691

7 January 2021

ATM, a central controller of cellular responses to DNA damage.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206691

7 January 2021

Involvement of the cohesin protein, Smc1, in Atm-dependent and independent responses to DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206691

7 January 2021

A translationally regulated Tousled kinase phosphorylates histone H3 and confers radioresistance when overexpressed

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206691

7 January 2021

ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206691

7 January 2021

Human Asf1 and CAF-1 interact and synergize in a repair-coupled nucleosome assembly pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206691

7 January 2021

Interaction of FANCD2 and NBS1 in the DNA damage response

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206691

7 January 2021

UV-induced hyperphosphorylation of replication protein a depends on DNA replication and expression of ATM protein.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206691

7 January 2021

The Tousled gene in A. thaliana encodes a protein kinase homolog that is required for leaf and flower development

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206691

7 January 2021

Characterization of homologous recombination induced by replication inhibition in mammalian cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206691

7 January 2021

Spontaneous DNA damage, genome instability, and cancer--when DNA replication escapes control.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206691

7 January 2021

Ataxia-telangiectasia and the ATM gene: linking neurodegeneration, immunodeficiency, and cancer to cell cycle checkpoints

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206691

7 January 2021

Identification of human Asf1 chromatin assembly factors as substrates of Tousled-like kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206691

7 January 2021

Mammalian homologues of the plant Tousled gene code for cell-cycle-regulated kinases with maximal activities linked to ongoing DNA replication

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206691

7 January 2021

A role for ATR in the DNA damage-induced phosphorylation of p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206691

7 January 2021

Functional interactions between BRCA1 and the checkpoint kinase ATR during genotoxic stress

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206691

7 January 2021

Cellular localisation of the ataxia-telangiectasia (ATM) gene product and discrimination between mutated and normal forms

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206691

7 January 2021

SMC1 is a downstream effector in the ATM/NBS1 branch of the human S-phase checkpoint

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206691

7 January 2021

ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206691

7 January 2021

The DNA damage response: putting checkpoints in perspective

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206691

7 January 2021