(Q30804251)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11821419%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

title

Determination of substrate motifs for human Chk1 and hCds1/Chk2 by the oriented peptide library approach (English)

1 reference

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6 December 2019

4

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6 December 2019

author name string

Ted O'Neill

1

1 reference

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6 December 2019

Lauren Giarratani

2

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6 December 2019

Ping Chen

3

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6 December 2019

Chang-Hun Lee

5

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6 December 2019

Matthew Bobiak

6

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6 December 2019

Fumihiko Kanai

7

1 reference

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6 December 2019

Bin-Bing Zhou

8

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6 December 2019

Jay H Chung

9

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6 December 2019

Gary A Rathbun

10

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6 December 2019

language of work or name

English

0 references

publication date

30 January 2002

1 reference

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Journal of Biological Chemistry

6 December 2019

published in

1 reference

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6 December 2019

volume

277

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6 December 2019

page(s)

16102-16115

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6 December 2019

issue

18

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Cell-cycle checkpoint kinases: checking in on the cell cycle

6 December 2019

cites work

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The G2-phase DNA-damage checkpoint

21 January 2018

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The rad3+ gene of Schizosaccharomyces pombe is involved in multiple checkpoint functions and in DNA repair

21 January 2018

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Isolation and characterization of the Schizosaccharomyces pombe rad3 gene, involved in the DNA damage and DNA synthesis checkpoints

21 January 2018

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Mitotic checkpoint genes in budding yeast and the dependence of mitosis on DNA replication and repair

21 January 2018

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An essential gene, ESR1, is required for mitotic cell growth, DNA repair and meiotic recombination in Saccharomyces cerevisiae

21 January 2018

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The complete sequence of the coding region of the ATM gene reveals similarity to cell cycle regulators in different species

21 January 2018

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cDNA cloning and gene mapping of a candidate human cell cycle checkpoint protein

21 January 2018

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Molecular cloning of mei-41, a gene that influences both somatic and germline chromosome metabolism of Drosophila melanogaster

21 January 2018

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The mei-41 gene of D. melanogaster is a structural and functional homolog of the human ataxia telangiectasia gene

21 January 2018

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Isolation and characterization of Xenopus ATM (X-ATM): expression, localization, and complex formation during oogenesis and early development

21 January 2018

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A kinase from fission yeast responsible for blocking mitosis in S phase.

21 January 2018

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The SAD1/RAD53 protein kinase controls multiple checkpoints and DNA damage-induced transcription in yeast

21 January 2018

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SPK1 is an essential S-phase-specific gene of Saccharomyces cerevisiae that encodes a nuclear serine/threonine/tyrosine kinase.

21 January 2018

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Requirement for Atr in phosphorylation of Chk1 and cell cycle regulation in response to DNA replication blocks and UV-damaged DNA in Xenopus egg extracts

21 January 2018

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21 January 2018

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A human homologue of the checkpoint kinase Cds1 directly inhibits Cdc25 phosphatase

21 January 2018

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Linkage of ATM to cell cycle regulation by the Chk2 protein kinase

21 January 2018

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Mammalian Chk2 is a downstream effector of the ATM-dependent DNA damage checkpoint pathway

21 January 2018

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Fission yeast chk1 protein kinase links the rad checkpoint pathway to cdc2.

21 January 2018

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rad-dependent response of the chk1-encoded protein kinase at the DNA damage checkpoint.

21 January 2018

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DNA damage and replication checkpoints in fission yeast require nuclear exclusion of the Cdc25 phosphatase via 14-3-3 binding

21 January 2018

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Nuclear localization of Cdc25 is regulated by DNA damage and a 14-3-3 protein

21 January 2018

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Cdc25 inhibited in vivo and in vitro by checkpoint kinases Cds1 and Chk1

21 January 2018

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Damage tolerance protein Mus81 associates with the FHA1 domain of checkpoint kinase Cds1

21 January 2018

1 reference

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S-phase-specific activation of Cds1 kinase defines a subpathway of the checkpoint response in Schizosaccharomyces pombe

21 January 2018

1 reference

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Basis for the checkpoint signal specificity that regulates Chk1 and Cds1 protein kinases

21 January 2018

1 reference

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Mik1 levels accumulate in S phase and may mediate an intrinsic link between S phase and mitosis

21 January 2018

1 reference

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Response of Xenopus Cds1 in cell-free extracts to DNA templates with double-stranded ends

21 January 2018

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DNA-replication checkpoint control at the Drosophila midblastula transition

21 January 2018

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A novel Drosophila nuclear protein serine/threonine kinase expressed in the germline during its establishment.

21 January 2018

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Critical role of Caenorhabditis elegans homologs of Cds1 (Chk2)-related kinases in meiotic recombination

21 January 2018

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Drosophila Chk2 is required for DNA damage-mediated cell cycle arrest and apoptosis.

21 January 2018

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Ataxia telangiectasia-mutated phosphorylates Chk2 in vivo and in vitro

21 January 2018

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Caffeine abolishes the mammalian G(2)/M DNA damage checkpoint by inhibiting ataxia-telangiectasia-mutated kinase activity

21 January 2018

1 reference

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The hCds1 (Chk2)-FHA domain is essential for a chain of phosphorylation events on hCds1 that is induced by ionizing radiation

21 January 2018

1 reference

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ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1

21 January 2018

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DNA damage-induced activation of p53 by the checkpoint kinase Chk2

21 January 2018

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hCds1-mediated phosphorylation of BRCA1 regulates the DNA damage response

21 January 2018

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The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis

21 January 2018

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Conservation of the Chk1 checkpoint pathway in mammals: linkage of DNA damage to Cdk regulation through Cdc25

21 January 2018

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Use of an oriented peptide library to determine the optimal substrates of protein kinases

21 January 2018

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Utilization of oriented peptide libraries to identify substrate motifs selected by ATM.

21 January 2018

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Enhanced phosphorylation of p53 by ATM in response to DNA damage

21 January 2018

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Activation of the ATM kinase by ionizing radiation and phosphorylation of p53

21 January 2018

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Determination of the specific substrate sequence motifs of protein kinase C isozymes

21 January 2018

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Peptide and protein library screening defines optimal substrate motifs for AKT/PKB.

21 January 2018

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A motif-based profile scanning approach for genome-wide prediction of signaling pathways

21 January 2018

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Absence of apparent phenotype in mice lacking Cdc25C protein phosphatase

21 January 2018

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A structural basis for substrate specificities of protein Ser/Thr kinases: primary sequence preference of casein kinases I and II, NIMA, phosphorylase kinase, calmodulin-dependent kinase II, CDK5, and Erk1.

21 January 2018

1 reference

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The AMP-activated/SNF1 protein kinase subfamily: metabolic sensors of the eukaryotic cell?

21 January 2018

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The 1.7 A crystal structure of human cell cycle checkpoint kinase Chk1: implications for Chk1 regulation

21 January 2018

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Active and inactive protein kinases: structural basis for regulation

21 January 2018

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Activation of rat liver AMP-activated protein kinase by kinase kinase in a purified, reconstituted system. Effects of AMP and AMP analogues.

21 January 2018

1 reference

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Claspin, a novel protein required for the activation of Chk1 during a DNA replication checkpoint response in Xenopus egg extracts

21 January 2018

1 reference

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The Chk1 protein kinase and the Cdc25C regulatory pathways are targets of the anticancer agent UCN-01

21 January 2018

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Heterozygous germ line hCHK2 mutations in Li-Fraumeni syndrome

21 January 2018

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Characterization of brain PCTAIRE-1 kinase immunoreactivity and its interactions with p11 and 14-3-3 proteins

21 January 2018

1 reference

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PCTAIRE 2, a Cdc2-related serine/threonine kinase, is predominantly expressed in terminally differentiated neurons

21 January 2018

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Multiple subcellular localizations of PCTAIRE-1 in brain.

21 January 2018

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Ataxia telangiectasia: new neurons and ATM.

21 January 2018

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Cellular localisation of the ataxia-telangiectasia (ATM) gene product and discrimination between mutated and normal forms

21 January 2018

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Expression of the ataxia-telangiectasia gene (ATM) product in human cerebellar neurons during development.

21 January 2018

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ATM immunolocalization in mouse neuronal endosomes: implications for ataxia-telangiectasia.

21 January 2018

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The crystal structure of a phosphorylase kinase peptide substrate complex: kinase substrate recognition

21 January 2018

1 reference

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Crystal structure of the catalytic subunit of cAMP-dependent protein kinase complexed with MgATP and peptide inhibitor

21 January 2018

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Checkpoints: How to activate p53

21 January 2018

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Cdc25 Mitotic Inducer Targeted by Chk1 DNA Damage Checkpoint Kinase

21 January 2018

1 reference

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Replication checkpoint requires phosphorylation of the phosphatase Cdc25 by Cds1 or Chk1

21 January 2018

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Fission yeast genes involved in coupling mitosis to completion of DNA replication

21 January 2018

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DNA damage checkpoints update: getting molecular

21 January 2018

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Control of the DNA damage checkpoint by chk1 and rad53 protein kinases through distinct mechanisms

21 January 2018

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DNA-replication/DNA-damage-dependent centrosome inactivation in Drosophila embryos

21 January 2018

1 reference

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Specific motifs recognized by the SH2 domains of Csk, 3BP2, fps/fes, GRB-2, HCP, SHC, Syk, and Vav

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111705200

Substrate specificity determinants of the checkpoint protein kinase Chk1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111705200

Cdc2 Phosphorylation of Crb2 Is Required for Reestablishing Cell Cycle Progression after the Damage Checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111705200

The Ded1 DEAD box helicase interacts with Chk1 and Cdc2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111705200

21 January 2018

Identifiers

DOI

10.1074/JBC.M111705200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11821419%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

1 reference