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Cell-cycle checkpoint kinases: checking in on the cell cycle
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scholarly article
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Europe PubMed Central
PubMed ID
11063934
retrieved
30 July 2017
review article
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Europe PubMed Central
title
Cell-cycle checkpoint kinases: checking in on the cell cycle
(English)
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Europe PubMed Central
PubMed ID
11063934
retrieved
30 July 2017
main subject
14-3-3epsilon Dmel_CG31196
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GOA release 2020-03-11
Grapes Dmel_CG17161
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GOA release 2020-03-11
Mutagen-sensitive 304 Dmel_CG7347
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GOA release 2020-03-11
Meiotic 41 Dmel_CG4252
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GOA release 2020-03-11
author name string
N C Walworth
series ordinal
1
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Europe PubMed Central
PubMed ID
11063934
retrieved
30 July 2017
language of work or name
English
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publication date
1 December 2000
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Europe PubMed Central
PubMed ID
11063934
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30 July 2017
published in
Current Opinion in Cell Biology
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stated in
Europe PubMed Central
PubMed ID
11063934
retrieved
30 July 2017
volume
12
1 reference
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Europe PubMed Central
PubMed ID
11063934
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30 July 2017
page(s)
697-704
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Europe PubMed Central
PubMed ID
11063934
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30 July 2017
issue
6
1 reference
stated in
Europe PubMed Central
PubMed ID
11063934
retrieved
30 July 2017
cites work
Checkpoints: controls that ensure the order of cell cycle events
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The G2-phase DNA-damage checkpoint
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Control of the DNA damage checkpoint by chk1 and rad53 protein kinases through distinct mechanisms
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7 January 2021
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Activating the DNA damage checkpoint in a developmental context.
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Initiation of genetic recombination and recombination-dependent replication
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Replication fork arrest and DNA recombination
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7 January 2021
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The Mre11 complex and ATM: collaborating to navigate S phase
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Sensing and responding to DNA damage.
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7 January 2021
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Checkpoint defects leading to premature mitosis also cause endoreplication of DNA in Aspergillus nidulans
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7 January 2021
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Splitting the ATM: distinct repair and checkpoint defects in ataxia–telangiectasia
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Heterozygous germ line hCHK2 mutations in Li-Fraumeni syndrome
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Targeted disruption of the cell-cycle checkpoint gene ATR leads to early embryonic lethality in mice
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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X
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7 January 2021
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DNA damage induces phosphorylation of the amino terminus of p53
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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X
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Regulation of the p53 tumor suppressor protein
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Rapid ATM-dependent phosphorylation of MDM2 precedes p53 accumulation in response to DNA damage
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Critical role for Ser20 of human p53 in the negative regulation of p53 by Mdm2.
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DNA damage-inducible phosphorylation of p53 at N-terminal sites including a novel site, Ser20, requires tetramerization
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Phosphorylation of Ser-20 mediates stabilization of human p53 in response to DNA damage
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Substrate specificities and identification of putative substrates of ATM kinase family members
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DNA damage-induced activation of p53 by the checkpoint kinase Chk2
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Caffeine abolishes the mammalian G(2)/M DNA damage checkpoint by inhibiting ataxia-telangiectasia-mutated kinase activity
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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X
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7 January 2021
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Linkage of ATM to cell cycle regulation by the Chk2 protein kinase
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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X
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Mutations in serines 15 and 20 of human p53 impair its apoptotic activity.
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Serine15 phosphorylation stimulates p53 transactivation but does not directly influence interaction with HDM2.
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Distinct Initiation and Maintenance Mechanisms Cooperate to Induce G1 Cell Cycle Arrest in Response to DNA Damage
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Drosophila p53 is a structural and functional homolog of the tumor suppressor p53.
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Drosophila p53 binds a damage response element at the reaper locus
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Identification and characterization of a p53 homologue in Drosophila melanogaster
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A human Cds1-related kinase that functions downstream of ATM protein in the cellular response to DNA damage
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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X
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7 January 2021
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A human homologue of the checkpoint kinase Cds1 directly inhibits Cdc25 phosphatase
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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X
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7 January 2021
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Mammalian Chk2 is a downstream effector of the ATM-dependent DNA damage checkpoint pathway
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S-phase-specific activation of Cds1 kinase defines a subpathway of the checkpoint response in Schizosaccharomyces pombe
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Spk1/Rad53 is regulated by Mec1-dependent protein phosphorylation in DNA replication and damage checkpoint pathways
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Response of Xenopus Cds1 in cell-free extracts to DNA templates with double-stranded ends
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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X
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7 January 2021
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Checkpoints on the road to mitosis
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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X
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7 January 2021
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A kinase from fission yeast responsible for blocking mitosis in S phase.
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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X
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7 January 2021
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Cell cycle regulation of Dfp1, an activator of the Hsk1 protein kinase
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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X
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7 January 2021
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A Mec1- and Rad53-dependent checkpoint controls late-firing origins of DNA replication
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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X
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7 January 2021
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Regulation of DNA-replication origins during cell-cycle progression
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p53 is required for radiation-induced apoptosis in mouse thymocytes
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7 January 2021
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Thymocyte apoptosis induced by p53-dependent and independent pathways.
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7 January 2021
based on heuristic
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Ataxia-telangiectasia and the ATM gene: linking neurodegeneration, immunodeficiency, and cancer to cell cycle checkpoints
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
DNA-replication checkpoint control at the Drosophila midblastula transition
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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X
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7 January 2021
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The Drosophila ATM homologue Mei-41 has an essential checkpoint function at the midblastula transition.
1 reference
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7 January 2021
based on heuristic
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The Drosophila grapes gene is related to checkpoint gene chk1/rad27 and is required for late syncytial division fidelity
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7 January 2021
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Chromosome missegregation and apoptosis in mice lacking the mitotic checkpoint protein Mad2
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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X
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based on heuristic
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Histone H1 dephosphorylation is mediated through a radiation-induced signal transduction pathway dependent on ATM.
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X
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7 January 2021
based on heuristic
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Sensing of ionizing radiation-induced DNA damage by ATM through interaction with histone deacetylase
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular association between ATR and two components of the nucleosome remodeling and deacetylating complex, HDAC2 and CHD4
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X
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7 January 2021
based on heuristic
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ES cells do not activate p53-dependent stress responses and undergo p53-independent apoptosis in response to DNA damage
1 reference
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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X
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7 January 2021
based on heuristic
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UCN-01 selectively enhances mitomycin C cytotoxicity in p53 defective cells which is mediated through S and/or G(2) checkpoint abrogation
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X
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Caffeine-induced uncoupling of mitosis from the completion of DNA replication in mammalian cells
1 reference
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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanism by which caffeine potentiates lethality of nitrogen mustard
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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Caffeine inhibits the checkpoint kinase ATM
1 reference
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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X
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7 January 2021
based on heuristic
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The 1.7 A crystal structure of human cell cycle checkpoint kinase Chk1: implications for Chk1 regulation
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X
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7 January 2021
based on heuristic
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Damage and replication checkpoint control in fission yeast is ensured by interactions of Crb2, a protein with BRCT motif, with Cut5 and Chk1.
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Isolation and characterization of the Schizosaccharomyces pombe rhp9 gene: a gene required for the DNA damage checkpoint but not the replication checkpoint
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
DNA polymerase delta is required for the replication feedback control of cell cycle progression in Schizosaccharomyces pombe
1 reference
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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X
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7 January 2021
based on heuristic
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Cid1, a fission yeast protein required for S-M checkpoint control when DNA polymerase delta or epsilon is inactivated
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X
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7 January 2021
based on heuristic
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The S / M checkpoint at 37˚C and the recovery of viability of the mutant pol δ ts3 require the crb2 + /rhp9 + gene in fission yeast
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Analysis of Rad3 and Chk1 protein kinases defines different checkpoint responses.
1 reference
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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
The Pds1 anaphase inhibitor and Mec1 kinase define distinct checkpoints coupling S phase with mitosis in budding yeast
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Mutational effect of fission yeast polalpha on cell cycle events
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0955-0674(00)00154-X
1 reference
stated in
Europe PubMed Central
PubMed ID
11063934
retrieved
30 July 2017
PubMed ID
11063934
1 reference
stated in
Europe PubMed Central
PubMed ID
11063934
retrieved
30 July 2017
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