(Q28206435)

3

object named as

Giovambattista De Sarro

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author name string

Randal X Moldrich

1

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Astrid G Chapman

2

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Giovambattista De Sarro

3

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Brian S Meldrum

European Journal of Pharmacology

4

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language of work or name

English

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publication date

22 August 2003

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published in

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volume

476

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issue

1-2

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page(s)

3-16

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cites work

Anti-epileptogenic and anticonvulsant activity of L-2-amino-4-phosphonobutyrate, a presynaptic glutamate receptor agonist.

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Altered expression of group I metabotropic glutamate receptors in the hippocampus of amygdala-kindled rats.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Lasting increase in excitatory amino acid receptor-mediated polyphosphoinositide hydrolysis in the amygdala/pyriform cortex of amygdala-kindled rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Long-lasting enhancement of metabotropic excitatory amino acid receptor-mediated polyphosphoinositide hydrolysis in the amygdala/ pyriform cortex of deep prepiriform cortical kindled rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Long-lasting increase in protein kinase C activity in the hippocampus of amygdala-kindled rat

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Coordinate regulation of metabotropic glutamate receptors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Metabotropic glutamate receptors: electrophysiological properties and role in plasticity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Upregulation of metabotropic glutamate receptor subtype mGluR3 and mGluR5 in reactive astrocytes in a rat model of mesial temporal lobe epilepsy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Blockade of both epileptogenesis and glutamate release by (1S,3S)-ACPD, a presynaptic glutamate receptor agonist

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Anticonvulsant and glutamate release-inhibiting properties of the highly potent metabotropic glutamate receptor agonist (2S,2'R, 3'R)-2-(2',3'-dicarboxycyclopropyl)glycine (DCG-IV).

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Specific group II metabotropic glutamate receptor activation inhibits the development of kindled epilepsy in rats.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Selective blockade of type-1 metabotropic glutamate receptors induces neuroprotection by enhancing gabaergic transmission

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Limbic seizure and brain damage produced by kainic acid: mechanisms and relevance to human temporal lobe epilepsy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Temporal lobe epilepsy associated up-regulation of metabotropic glutamate receptors: correlated changes in mGluR1 mRNA and protein expression in experimental animals and human patients

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

7 January 2021

New antiepileptic drugs

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Ligands for glutamate receptors: design and therapeutic prospects

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

BAY36-7620: a potent non-competitive mGlu1 receptor antagonist with inverse agonist activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Regulation of neurotransmitter release by metabotropic glutamate receptors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

The anticonvulsant effect of the non-NMDA antagonists, NBQX and GYKI 52466, in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Anticonvulsant actions of LY 367385 ((+)-2-methyl-4-carboxyphenylglycine) and AIDA ((RS)-1-aminoindan-1,5-dicarboxylic acid).

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Anticonvulsant activity of a metabotropic glutamate receptor 8 preferential agonist, (R,S)-4-phosphonophenylglycine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Anticonvulsant activity of two metabotropic glutamate group I antagonists selective for the mGlu5 receptor: 2-methyl-6-(phenylethynyl)-pyridine (MPEP), and (E)-6-methyl-2-styryl-pyridine (SIB 1893).

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Anticonvulsant activity of a mGlu(4alpha) receptor selective agonist, (1S,3R,4S)-1-aminocyclopentane-1,2,4-tricarboxylic acid

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Pharmacology and functions of metabotropic glutamate receptors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Mechanisms of metabotropic glutamate receptor desensitization: role in the patterning of effector enzyme activation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

1,4-Benzodiazepine derivatives as anticonvulsant agents in DBA/2 mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Topiramate potentiates the antiseizure activity of some anticonvulsants in DBA/2 mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Group III mGlu receptor agonists potentiate the anticonvulsant effect of AMPA and NMDA receptor block

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

The roles of metabotropic glutamate receptors in seizures and epilepsy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

(RS)-2-chloro-5-hydroxyphenylglycine (CHPG) activates mGlu5, but no mGlu1, receptors expressed in CHO cells and potentiates NMDA responses in the hippocampus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Neuroprotection mediated by glial group-II metabotropic glutamate receptors requires the activation of the MAP kinase and the phosphatidylinositol-3-kinase pathways.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Attenuation of seizures induced by homocysteic acid in immature rats by metabotropic glutamate group II and group III receptor agonists

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Seizures induced by homocysteic acid in immature rats are prevented by group III metabotropic glutamate receptoragonist (R,S)-4-phosphonophenylglycine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Analysing metabotropic glutamate group III receptor mediated modulation of synaptic transmission in the amygdala-kindled dentate gyrus of the rat.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Allosteric modulators of group I metabotropic glutamate receptors: novel subtype-selective ligands and therapeutic perspectives.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Performance deficits of mGluR8 knockout mice in learning tasks: the effects of null mutation and the background genotype.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Convulsant and anticonvulsant actions of agonists and antagonists of group III mGluRs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Effects of levetiracetam, a novel antiepileptic drug, on convulsant activity in two genetic rat models of epilepsy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Inhibition of hippocampal kindling by metabotropic glutamate receptor antisense oligonucleotides

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Metabotropic glutamate receptor 1-induced upregulation of NMDA receptor current: mediation through the Pyk2/Src-family kinase pathway in cortical neurons.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Reversible and non-competitive antagonist profile of CPCCOEt at the human type 1alpha metabotropic glutamate receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Loss of mGluR-mediated hyperpolarizations and increase in mGluR depolarizations in basolateral amygdala neurons in kindling-induced epilepsy.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Cloning, expression, and gene structure of a G protein-coupled glutamate receptor from rat brain.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Clonazepam suppresses GABAB-mediated inhibition in thalamic relay neurons through effects in nucleus reticularis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Convulsions induced in 10-day-old rats by intraperitional injection of monosodium glutamate and related excitant amino acids

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Epileptogenesis up-regulates metabotropic glutamate receptor activation of sodium-calcium exchange current in the amygdala.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Inhibition of group I metabotropic glutamate receptor responses in vivo in rats by a new generation of carboxyphenylglycine-like amino acid antagonists

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Decreased sensitivity to Group III mGluR agonists in the lateral perforant path following kindling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Down-regulation of mGluR8 in pilocarpine epileptic rats.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

In vitro and in vivo characterization of MPEP, an allosteric modulator of the metabotropic glutamate receptor subtype 5: review article

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Complex interactions between mGluR1 and mGluR5 shape neuronal network activity in the rat hippocampus.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Up-regulation of the metabotropic glutamate receptor mGluR4 in hippocampal neurons with reduced seizure vulnerability

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Metabotropic glutamate receptors 1 and 5 differentially regulate CA1 pyramidal cell function.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Activation of group I metabotropic glutamate receptors produces a direct excitation and disinhibition of GABAergic projection neurons in the substantia nigra pars reticulata.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Positive allosteric modulation of the human metabotropic glutamate receptor 4 (hmGluR4) by SIB-1893 and MPEP

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Sequence and expression of a metabotropic glutamate receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Kainate-induced status epilepticus leads to a delayed increase in various specific glutamate metabotropic receptor responses in the hippocampus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

9. Excitotoxicity and epileptic brain damage

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Glutamate receptors and transporters in genetic and acquired models of epilepsy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Differential roles for mGluR1 and mGluR5 in the persistent prolongation of epileptiform bursts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Changes in metabotropic glutamate receptor 1-8 gene expression in the rodent basal ganglia motor loop following lesion of the nigrostriatal tract

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Phosphorylation and calmodulin binding of the metabotropic glutamate receptor subtype 5 (mGluR5) are antagonistic in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Long-term potentiation of mGluR1 activity by depolarization-induced Homer1a in mouse cerebellar Purkinje neurons

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Anticonvulsive and neuroprotective actions of a potent agonist (DCG-IV) for group II metabotropic glutamate receptors against intraventricular kainate in the rat.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Emerging signalling and protein interactions mediated via metabotropic glutamate receptors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Anticonvulsant activity of 3,4-dicarboxyphenylglycines in DBA/2 mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Anti-epileptic activity of group II metabotropic glutamate receptor agonists (--)-2-oxa-4-aminobicyclo[3.1.0]hexane-4,6-dicarboxylate (LY379268) and (--)-2-thia-4-aminobicyclo[3.1.0]hexane-4,6-dicarboxylate (LY389795).

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

The mGlu(2/3) agonist 2R,4R-4-aminopyrrolidine-2,4-dicarboxylate, is anti- and proconvulsant in DBA/2 mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Glutamate receptors: brain function and signal transduction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Epileptogenesis in vivo enhances the sensitivity of inhibitory presynaptic metabotropic glutamate receptors in basolateral amygdala neurons in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Cocaine and kindling alter the sensitivity of group II and III metabotropic glutamate receptors in the central amygdala

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Calmodulin dependence of presynaptic metabotropic glutamate receptor signaling.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Selective mGluR5 antagonists MPEP and SIB-1893 decrease NMDA or glutamate-mediated neuronal toxicity through actions that reflect NMDA receptor antagonism

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

The non-competitive antagonists 2-methyl-6-(phenylethynyl)pyridine and 7-hydroxyiminocyclopropan[b]chromen-1a-carboxylic acid ethyl ester interact with overlapping binding pockets in the transmembrane region of group I metabotropic glutamate recepto

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

The metabotropic glutamate receptors: structure, activation mechanism and pharmacology

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

New perspectives for the development of selective metabotropic glutamate receptor ligands.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Kindling-induced overexpression of Homer 1A and its functional implications for epileptogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

AIDA, a class I metabotropic glutamate-receptor antagonist limits kainate-induced hippocampal dysfunction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Distribution and roles of metabotropic glutamate receptors in the basal ganglia motor circuit: implications for treatment of Parkinson's disease and related disorders

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Increased seizure susceptibility in mice lacking metabotropic glutamate receptor 7

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

cAMP-dependent protein kinase inhibits mGluR2 coupling to G-proteins by direct receptor phosphorylation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

The novel metabotropic glutamate receptor agonist 2R,4R-APDC potentiates stimulation of phosphoinositide hydrolysis in the rat hippocampus by 3,5-dihydroxyphenylglycine: evidence for a synergistic interaction between group 1 and group 2 receptors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Pharmacological agents acting at subtypes of metabotropic glutamate receptors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Differential presynaptic localization of metabotropic glutamate receptor subtypes in the rat hippocampus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Glutamate stimulates inositol phosphate formation in striatal neurones

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Modulation of absence seizures by the GABA(A) receptor: a critical rolefor metabotropic glutamate receptor 4 (mGluR4).

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Determination of group I metabotropic glutamate receptor subtypes involved in the frequency of epileptiform activity in vitro using mGluR1 and mGluR5 mutant mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

A new type of glutamate receptor linked to inositol phospholipid metabolism

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Anticonvulsant action of metabotropic glutamate receptor agonists in kindled amygdala of rats.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

A family of metabotropic glutamate receptors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Distribution of metabotropic glutamate receptor mGluR3 in the mouse CNS: differential location relative to pre- and postsynaptic sites

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Expression of the group II and III metabotropic glutamate receptors in the hippocampus of patients with mesial temporal lobe epilepsy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Prolonged anticonvulsant action of glutamate metabotropic receptor agonists in inferior colliculus of genetically epilepsy-prone rats.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Metabotropic glutamate receptor 8 in the rat hippocampus after pilocarpine induced status epilepticus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Expression of metabotropic glutamate receptor 1alpha in the hippocampus of rat pilocarpine model of status epilepticus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Expression of the group I metabotropic glutamate receptor in the hippocampus of patients with mesial temporal lobe epilepsy.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

(S)-3,4-DCPG, a potent and selective mGlu8a receptor agonist, activates metabotropic glutamate receptors on primary afferent terminals in the neonatal rat spinal cord

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

(S)-4-carboxy-3-hydroxyphenylglycine, an antagonist of metabotropic glutamate receptor (mGluR) 1a and an agonist of mGluR2, protects against audiogenic seizures in DBA/2 mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Group I mGluRs modulate the pattern of non-synaptic epileptiform activity in the hippocampus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Intracerebral 1S,3R-1-aminocyclopentane-1,3-dicarboxylic acid (1S,3R-ACPD) produces limbic seizures that are not blocked by ionotropic glutamate receptor antagonists

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Induction or protection of limbic seizures in mice by mGluR subtype selective agonists

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Roles of metabotropic glutamate receptors in glial function and glial-neuronal communication

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6

Elevated levels of group-III metabotropic glutamate receptors in the inferior colliculus of genetically epilepsy-prone rats following intracollicular administration of L-serine-O-phosphate

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2803%2902149-6