(Q28211046)

English

Hematopoietic progenitor kinase 1 associates physically and functionally with the adaptor proteins B cell linker protein and SLP-76 in lymphocytes

scientific article (publication date: 30 November 2001)

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scholarly article

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Hematopoietic progenitor kinase 1 associates physically and functionally with the adaptor proteins B cell linker protein and SLP-76 in lymphocytes (English)

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author name string

K Sauer

1

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J Liou

2

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S B Singh

3

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D Yablonski

4

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A Weiss

5

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R M Perlmutter

6

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language of work or name

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publication date

30 November 2001

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Journal of Biological Chemistry

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276

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48

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45207-16

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Signal transduction from the B cell antigen-receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106811200

21 January 2018

Organization of complex situations in the immune system. Conference: signal processing through protein complexes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106811200

21 January 2018

Intracellular adapter molecules

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106811200

21 January 2018

The role of membrane-associated adaptors in T cell receptor signalling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106811200

21 January 2018

Signal transduction by the TCR for antigen

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106811200

21 January 2018

Adapter proteins in lymphocyte antigen-receptor signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106811200

21 January 2018

The role of lipid rafts in T cell antigen receptor (TCR) signalling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106811200

21 January 2018

HPK1 is activated by lymphocyte antigen receptors and negatively regulates AP-1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106811200

21 January 2018

The adaptor protein Gads (Grb2-related adaptor downstream of Shc) is implicated in coupling hemopoietic progenitor kinase-1 to the activated TCR.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106811200

21 January 2018

Involvement of hematopoietic progenitor kinase 1 in T cell receptor signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106811200

21 January 2018

Leukocyte-specific adaptor protein Grap2 interacts with hematopoietic progenitor kinase 1 (HPK1) to activate JNK signaling pathway in T lymphocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106811200

21 January 2018

Uncoupling of nonreceptor tyrosine kinases from PLC-gamma1 in an SLP-76-deficient T cell

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106811200

21 January 2018

Requirement for the leukocyte-specific adapter protein SLP-76 for normal T cell development

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106811200

21 January 2018

Impaired viability and profound block in thymocyte development in mice lacking the adaptor protein SLP-76.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106811200

21 January 2018

Molecular cloning of SLAP-130, an SLP-76-associated substrate of the T cell antigen receptor-stimulated protein tyrosine kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106811200

21 January 2018

Cloning of a novel T-cell protein FYB that binds FYN and SH2-domain-containing leukocyte protein 76 and modulates interleukin 2 production

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106811200

21 January 2018

Functional association between SLAP-130 and SLP-76 in Jurkat T cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106811200

21 January 2018

Novel isoform of lymphoid adaptor FYN-T-binding protein (FYB-130) interacts with SLP-76 and up-regulates interleukin 2 production

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106811200

21 January 2018

FYN-T-FYB-SLP-76 interactions define a T-cell receptor zeta/CD3-mediated tyrosine phosphorylation pathway that up-regulates interleukin 2 transcription in T-cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106811200

21 January 2018

BLNK: a central linker protein in B cell activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106811200

21 January 2018

SLP-65: a new signaling component in B lymphocytes which requires expression of the antigen receptor for phosphorylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106811200

21 January 2018

Involvement of LAT, Gads, and Grb2 in compartmentation of SLP-76 to the plasma membrane

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106811200

21 January 2018

BLNK: connecting Syk and Btk to calcium signals

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106811200

21 January 2018

Xid-like phenotypes: a B cell signalosome takes shape

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106811200

21 January 2018

BLNK required for coupling Syk to PLC gamma 2 and Rac1-JNK in B cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106811200

21 January 2018

Abnormal development and function of B lymphocytes in mice deficient for the signaling adaptor protein SLP-65

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106811200

21 January 2018

An essential role for BLNK in human B cell development

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106811200

21 January 2018

Requirement for B cell linker protein (BLNK) in B cell development

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106811200

21 January 2018

The B cell-restricted adaptor BASH is required for normal development and antigen receptor-mediated activation of B cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106811200

21 January 2018

Cbl suppresses B cell receptor-mediated phospholipase C (PLC)-gamma2 activation by regulating B cell linker protein-PLC-gamma2 binding

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106811200

21 January 2018

Human HPK1, a novel human hematopoietic progenitor kinase that activates the JNK/SAPK kinase cascade

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106811200

21 January 2018

Implication of the GRB2-associated phosphoprotein SLP-76 in T cell receptor-mediated interleukin 2 production

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106811200

21 January 2018

Crystal structures of c-Src reveal features of its autoinhibitory mechanism

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106811200

21 January 2018

Identification of a phospholipase C-gamma1 (PLC-gamma1) SH3 domain-binding site in SLP-76 required for T-cell receptor-mediated activation of PLC-gamma1 and NFAT

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106811200

21 January 2018

Regulatory and signaling properties of the Vav family

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106811200

21 January 2018

Recruitment of SLP-76 to the membrane and glycolipid-enriched membrane microdomains replaces the requirement for linker for activation of T cells in T cell receptor signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106811200

21 January 2018

Clnk, a novel SLP-76-related adaptor molecule expressed in cytokine-stimulated hemopoietic cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106811200

21 January 2018

A BASH/SLP-76-related adaptor protein MIST/Clnk involved in IgE receptor-mediated mast cell degranulation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106811200

21 January 2018

Modular peptide recognition domains in eukaryotic signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106811200

21 January 2018

Recognition and regulation of primary-sequence motifs by signaling modular domains

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106811200

21 January 2018

Vav and SLP-76 interact and functionally cooperate in IL-2 gene activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106811200

21 January 2018

Differential regulation of activation-induced tyrosine phosphorylation and recruitment of SLP-76 to Vav by distinct isoforms of the CD45 protein-tyrosine phosphatase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106811200

21 January 2018

Catalytic specificity of phosphotyrosine kinases Blk, Lyn, c-Src and Syk as assessed by phage display

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106811200

21 January 2018

Catalytic specificity of protein-tyrosine kinases is critical for selective signalling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106811200

21 January 2018

Modified phage peptide libraries as a tool to study specificity of phosphorylation and recognition of tyrosine containing peptides

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106811200

21 January 2018

Rapid identification of phosphopeptide ligands for SH2 domains. Screening of peptide libraries by fluorescence-activated bead sorting

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106811200

21 January 2018

Structure of the amino-terminal domain of Cbl complexed to its binding site on ZAP-70 kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106811200

21 January 2018

Novel mode of ligand binding by the SH2 domain of the human XLP disease gene product SAP/SH2D1A

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106811200

21 January 2018

Crystal structures of the XLP protein SAP reveal a class of SH2 domains with extended, phosphotyrosine-independent sequence recognition

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106811200

21 January 2018

Molecular interaction between the Fyn-associated protein SKAP55 and the SLP-76-associated phosphoprotein SLAP-130

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106811200

21 January 2018

FYB (FYN binding protein) serves as a binding partner for lymphoid protein and FYN kinase substrate SKAP55 and a SKAP55-related protein in T cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106811200

21 January 2018

SH2/SH3 adaptor proteins can link tyrosine kinases to a Ste20-related protein kinase, HPK1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106811200

21 January 2018

TcR zeta/CD3 signal transduction in T-cells: downstream signalling via ZAP-70, SLP-76 and FYB.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106811200

21 January 2018

Desensitization of Ras activation by a feedback disassociation of the SOS-Grb2 complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106811200

21 January 2018

Negative Feedback Regulation and Desensitization of Insulin- and Epidermal Growth Factor-stimulated p21ras Activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106811200

21 January 2018

Role of the Raf/mitogen-activated protein kinase pathway in p21ras desensitization

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106811200

21 January 2018

T cell receptor-induced phosphorylation of Sos requires activity of CD45, Lck, and protein kinase C, but not ERK.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106811200

21 January 2018

Hematopoietic progenitor kinase 1 is a component of transforming growth factor beta-induced c-Jun N-terminal kinase signaling cascade

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106811200

21 January 2018

The Ste20 group kinases as regulators of MAP kinase cascades

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106811200

21 January 2018

Signaling by the germinal center kinase family of protein kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106811200

21 January 2018

JNK is involved in signal integration during costimulation of T lymphocytes.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106811200

21 January 2018

Tyrosine-phosphorylated Vav1 as a point of integration for T-cell receptor- and CD28-mediated activation of JNK, p38, and interleukin-2 transcription

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106811200

21 January 2018

SMART, a simple modular architecture research tool: identification of signaling domains

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106811200

21 January 2018

c-rel regulation of IL-2 gene expression may be mediated through activation of AP-1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106811200

21 January 2018

Caspases: intracellular signaling by proteolysis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106811200

21 January 2018

Hematopoietic progenitor kinase-1 (HPK1) stress response signaling pathway activates IkappaB kinases (IKK-alpha/beta) and IKK-beta is a developmentally regulated protein kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106811200

21 January 2018

B cell adaptor containing src homology 2 domain (BASH) links B cell receptor signaling to the activation of hematopoietic progenitor kinase 1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106811200

21 January 2018

Epidermal Growth Factor Receptor Targeting Prevents Uncoupling of the Grb2-SOS Complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106811200

21 January 2018

Site specificity of p72 syk protein tyrosine kinase: efficient phosphorylation of motifs recognized by Src homology 2 domains of the Src family

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106811200

21 January 2018

Identifiers

10.1074/JBC.M106811200

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