(Q28236956)

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The adaptor molecule Lnk negatively regulates tumor necrosis factor-alpha-dependent VCAM-1 expression in endothelial cells through inhibition of the ERK1 and -2 pathways

scientific article (publication date: 21 July 2006)

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20 January 2020

The adaptor molecule Lnk negatively regulates tumor necrosis factor-alpha-dependent VCAM-1 expression in endothelial cells through inhibition of the ERK1 and -2 pathways (English)

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20 January 2020

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Gwénola Boulday

2

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20 January 2020

Thibaut Quillard

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20 January 2020

Beatrice Charreau

5

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20 January 2020

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Juliette Fitau

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20 January 2020

Flora Coulon

3

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publication date

27 April 2006

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20 January 2020

Journal of Biological Chemistry

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20 January 2020

281

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20 January 2020

20148-20159

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20 January 2020

29

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20 January 2020

Vascular development and disorders: molecular analysis and pathogenic insights

1 reference

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Cytokine regulation of endothelial cell function: from molecular level to the bedside

1 reference

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21 January 2018

Cloning and characterization of Lnk, a signal transduction protein that links T-cell receptor activation signal to phospholipase C gamma 1, Grb2, and phosphatidylinositol 3-kinase

1 reference

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21 January 2018

Characterization of Lnk. An adaptor protein expressed in lymphocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510997200

21 January 2018

Cloning and characterization of APS, an adaptor molecule containing PH and SH2 domains that is tyrosine phosphorylated upon B-cell receptor stimulation

1 reference

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21 January 2018

Cytokine signaling and hematopoietic homeostasis are disrupted in Lnk-deficient mice

1 reference

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21 January 2018

Control of B cell production by the adaptor protein lnk. Definition Of a conserved family of signal-modulating proteins

1 reference

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21 January 2018

Enhanced hematopoiesis by hematopoietic progenitor cells lacking intracellular adaptor protein, Lnk

1 reference

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21 January 2018

Regulation of hematopoietic development in the aorta-gonad-mesonephros region mediated by Lnk adaptor protein

1 reference

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21 January 2018

A simplified system for generating recombinant adenoviruses

1 reference

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21 January 2018

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510997200

21 January 2018

Lnk inhibits Tpo-mpl signaling and Tpo-mediated megakaryocytopoiesis

1 reference

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21 January 2018

Lnk inhibits erythropoiesis and Epo-dependent JAK2 activation and downstream signaling pathways

1 reference

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21 January 2018

NF-kappa B and I kappa B alpha: an inducible regulatory system in endothelial activation

1 reference

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21 January 2018

A phosphatidylinositol 3-kinase/Akt pathway, activated by tumor necrosis factor or interleukin-1, inhibits apoptosis but does not activate NFkappaB in human endothelial cells

1 reference

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21 January 2018

Tumor necrosis factor alpha-induced E-selectin expression is activated by the nuclear factor-kappaB and c-JUN N-terminal kinase/p38 mitogen-activated protein kinase pathways

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21 January 2018

Role of Akt signaling in vascular homeostasis and angiogenesis

1 reference

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21 January 2018

Acute activation of Erk1/Erk2 and protein kinase B/akt proceed by independent pathways in multiple cell types.

1 reference

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21 January 2018

Protein kinase Akt/PKB phosphorylates heme oxygenase-1 in vitro and in vivo

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21 January 2018

Modulation of endothelial cell apoptosis by heme oxygenase-1-derived carbon monoxide

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21 January 2018

Heme oxygenase-1 modulates the expression of adhesion molecules associated with endothelial cell activation.

1 reference

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21 January 2018

Involvement of PI3K/Akt pathway in cell cycle progression, apoptosis, and neoplastic transformation: a target for cancer chemotherapy.

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21 January 2018

Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases

1 reference

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21 January 2018

CD40 signaling of monocyte inflammatory cytokine synthesis through an ERK1/2-dependent pathway. A target of interleukin (il)-4 and il-10 anti-inflammatory action

1 reference

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21 January 2018

Role of activating protein-1 in the regulation of the vascular cell adhesion molecule-1 gene expression by tumor necrosis factor-alpha

1 reference

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21 January 2018

Temporal control of NF-kappaB activation by ERK differentially regulates interleukin-1beta-induced gene expression.

1 reference

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21 January 2018

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10.1074/JBC.M510997200

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16644735%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

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24 November 2022

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Europe PubMed Central

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20 January 2020

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