(Q28238688)

English

Biochemistry. KSR plays CRAF-ty

scientific article (publication date: 27 May 2011)

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title

Biochemistry. KSR plays CRAF-ty (English)

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Mark A Lemmon

2

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author name string

Fumin Shi

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1

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language of work or name

English

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publication date

27 May 2011

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published in

Science

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volume

332

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issue

6033

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page(s)

1043-4

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cites work

Scaffold proteins: hubs for controlling the flow of cellular information

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21 April 2017

A Raf-induced allosteric transition of KSR stimulates phosphorylation of MEK

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21 April 2017

Mutation that blocks ATP binding creates a pseudokinase stabilizing the scaffolding function of kinase suppressor of Ras, CRAF and BRAF

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21 April 2017

Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma

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21 April 2017

A dimerization-dependent mechanism drives RAF catalytic activation

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21 April 2017

CASK Functions as a Mg2+-independent neurexin kinase

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21 April 2017

ErbB3/HER3 intracellular domain is competent to bind ATP and catalyze autophosphorylation

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21 April 2017

Coordinating ERK/MAPK signalling through scaffolds and inhibitors

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21 April 2017

RAF inhibitor-induced KSR1/B-RAF binding and its effects on ERK cascade signaling

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21 January 2018

Signaling dynamics of the KSR1 scaffold complex

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21 January 2018

Mutant BRAF melanomas--dependence and resistance

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21 January 2018

Mechanistic principles of RAF kinase signaling

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reference URL

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21 January 2018

Pseudokinases-remnants of evolution or key allosteric regulators?

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21 January 2018

Drug discovery: inhibitors that activate

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21 January 2018

Identifiers

DOI

10.1126/SCIENCE.1208063

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PubMed publication ID

21617065

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(Q28238688)

Biochemistry. KSR plays CRAF-ty

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