(Q28240590)

English

Cysteine protease inhibitors reduce brain beta-amyloid and beta-secretase activity in vivo and are potential Alzheimer's disease therapeutics

scientific article (publication date: September 2007)

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scholarly article

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Cysteine protease inhibitors reduce brain beta-amyloid and beta-secretase activity in vivo and are potential Alzheimer's disease therapeutics (English)

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Alzheimer's disease

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based on heuristic

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author name string

Gregory Hook

1

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Vivian Y H Hook

2

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Mark Kindy

3

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language of work or name

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publication date

September 2007

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Biological Chemistry

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388

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9

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979-83

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Guinea pigs as a nontransgenic model for APP processing in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1515%2FBC.2007.117

21 January 2018

RAGE mediates amyloid-beta peptide transport across the blood-brain barrier and accumulation in brain

1 reference

https://api.crossref.org/works/10.1515%2FBC.2007.117

21 January 2018

Simvastatin strongly reduces levels of Alzheimer's disease beta -amyloid peptides Abeta 42 and Abeta 40 in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1515%2FBC.2007.117

21 January 2018

Inhibitors of cathepsin B.

1 reference

https://api.crossref.org/works/10.1515%2FBC.2007.117

21 January 2018

Evidence that inhibition of cathepsin-B contributes to the neuroprotective properties of caspase inhibitor Tyr-Val-Ala-Asp-chloromethyl ketone.

1 reference

https://api.crossref.org/works/10.1515%2FBC.2007.117

21 January 2018

Beta-amyloid peptide in regulated secretory vesicles of chromaffin cells: evidence for multiple cysteine proteolytic activities in distinct pathways for beta-secretase activity in chromaffin vesicles

1 reference

https://api.crossref.org/works/10.1515%2FBC.2007.117

21 January 2018

Inhibition of cathepsin B reduces beta-amyloid production in regulated secretory vesicles of neuronal chromaffin cells: evidence for cathepsin B as a candidate beta-secretase of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1515%2FBC.2007.117

21 January 2018

Cysteine protease inhibitors effectively reduce in vivo levels of brain beta-amyloid related to Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1515%2FBC.2007.117

21 January 2018

Conservation of the sequence of the Alzheimer's disease amyloid peptide in dog, polar bear and five other mammals by cross-species polymerase chain reaction analysis

1 reference

https://api.crossref.org/works/10.1515%2FBC.2007.117

21 January 2018

Neprilysin regulates amyloid Beta peptide levels

1 reference

https://api.crossref.org/works/10.1515%2FBC.2007.117

21 January 2018

Alzheimer's disease: perspectives for the new millennium

1 reference

https://api.crossref.org/works/10.1515%2FBC.2007.117

21 January 2018

Identifiers

10.1515/BC.2007.117

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