(Q28243054)

English

Bone marrow stromal cells protect lymphoma B-cells from rituximab-induced apoptosis and targeting integrin α-4-β-1 (VLA-4) with natalizumab can overcome this resistance

scientific article (publication date: October 2011)

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Bone marrow stromal cells protect lymphoma B-cells from rituximab-induced apoptosis and targeting integrin α-4-β-1 (VLA-4) with natalizumab can overcome this resistance (English)

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1 reference

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8

object named as

Anne J Novak

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object named as

Marek Mraz

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2

object named as

Clive S Zent

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Diane F. Jelinek

4

object named as

Diane F Jelinek

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object named as

Neil E Kay

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author name string

Amy K Church

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Xiaosheng Wu

5

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Sarka Pospisilova

6

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Stephen M Ansell

7

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Thomas E Witzig

10

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Grzegorz S Nowakowski

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language of work or name

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publication date

October 2011

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British Journal of Haematology

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155

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1

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53-64

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1 reference

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Alpha4 integrins and the immune response

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The chemokine receptor CCR7 and alpha4 integrin are important for migration of chronic lymphocytic leukemia cells into lymph nodes

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Rituximab maintenance treatment of relapsed/resistant follicular non-Hodgkin's lymphoma: long-term outcome of the EORTC 20981 phase III randomized intergroup study

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29 September 2017

Antigenic modulation and rituximab resistance

1 reference

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29 September 2017

Rituximab inhibits B-cell receptor signaling.

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Rituximab-mediated cell signaling and chemo/immuno-sensitization of drug-resistant B-NHL is independent of its Fc functions.

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The microenvironment in mature B-cell malignancies: a target for new treatment strategies

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The role of natalizumab in hematopoietic stem cell mobilization

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CD38 at the junction between prognostic marker and therapeutic target.

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CD49d expression is an independent predictor of overall survival in patients with chronic lymphocytic leukaemia: a prognostic parameter with therapeutic potential

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29 September 2017

Rituximab-induced inhibition of antiapoptotic cell survival pathways: implications in chemo/immunoresistance, rituximab unresponsiveness, prognostic and novel therapeutic interventions

1 reference

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29 September 2017

Bone marrow stromal cells prevent apoptosis of lymphoma cells by upregulation of anti-apoptotic proteins associated with activation of NF-kappaB (RelB/p52) in non-Hodgkin's lymphoma cells

1 reference

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29 September 2017

Bone biopsy derived marrow stromal elements rescue chronic lymphocytic leukemia B-cells from spontaneous and drug induced cell death and facilitates an "angiogenic switch".

1 reference

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29 September 2017

Small peptide inhibitors of the CXCR4 chemokine receptor (CD184) antagonize the activation, migration, and antiapoptotic responses of CXCL12 in chronic lymphocytic leukemia B cells.

1 reference

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29 September 2017

Anti-alpha4 integrin therapy for multiple sclerosis: mechanisms and rationale.

1 reference

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29 September 2017

Rituximab (monoclonal anti-CD20 antibody): mechanisms of action and resistance

1 reference

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29 September 2017

Role of integrins in cell invasion and migration

1 reference

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29 September 2017

Integrin-dependence of lymphocyte entry into the splenic white pulp

1 reference

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Drug resistance and drug development in multiple myeloma

1 reference

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29 September 2017

CD20-mediated apoptosis: signalling through lipid rafts

1 reference

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29 September 2017

Survival of B lineage leukemic cells: signals from the bone marrow microenvironment

1 reference

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29 September 2017

VLA-4 mediated adhesion to bone marrow stromal cells confers chemoresistance to adherent lymphoma cells

1 reference

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Survival signals within the tumour microenvironment suppress drug-induced apoptosis: lessons learned from B lymphomas

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Rheumatoid arthritis synovial stromal cells inhibit apoptosis and up-regulate Bcl-xL expression by B cells in a CD49/CD29-CD106-dependent mechanism

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Phase II multicenter study of human CD52 antibody in previously treated chronic lymphocytic leukemia. European Study Group of CAMPATH-1H Treatment in Chronic Lymphocytic Leukemia

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The alpha 4 beta 1 fibronectin ligands CS-1, Hep II, and RGD induce different intracellular events in B lymphoid cells. Comparison with the effects of the endothelial ligand VCAM-1.

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Evidence for a role of the integrin VLA-4 in lympho-hemopoiesis

1 reference

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29 September 2017

Identification of a novel recognition sequence for the integrin alpha 4 beta 1 in the COOH-terminal heparin-binding domain of fibronectin

1 reference

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1 reference

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1 reference

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2 June 2018

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1 reference

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Differential expression of very late activation antigen-3 (VLA-3)/VLA-4 in B-cell non-Hodgkin lymphoma and B-cell chronic lymphocytic leukemia

1 reference

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2 June 2018

Spleen tyrosine kinase inhibition prevents chemokine- and integrin-mediated stromal protective effects in chronic lymphocytic leukemia

1 reference

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21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08794.X

21 January 2018

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R-ESHAP as salvage therapy for patients with relapsed or refractory diffuse large B-cell lymphoma: the influence of prior exposure to rituximab on outcome. A GEL/TAMO study.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08794.X

21 January 2018

Interaction between leukemic-cell VLA-4 and stromal fibronectin is a decisive factor for minimal residual disease of acute myelogenous leukemia

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08794.X

21 January 2018

CD49d expression is an independent risk factor of progressive disease in early stage chronic lymphocytic leukemia.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08794.X

21 January 2018

Inhibition of CXCR4 with the novel RCP168 peptide overcomes stroma-mediated chemoresistance in chronic and acute leukemias.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08794.X

21 January 2018

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1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08794.X

21 January 2018

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1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08794.X

21 January 2018

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4405035

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Adhesion through the LFA-1 (CD11a/CD18)-ICAM-1 (CD54) and the VLA-4 (CD49d)-VCAM-1 (CD106) pathways prevents apoptosis of germinal center B cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4405035

27 November 2018

Signaling events involved in anti-CD20-induced apoptosis of malignant human B cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21749361

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Engineering antibodies for therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/21749361

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CXCR4 neutralization, a novel therapeutic approach for non-Hodgkin's lymphoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/21749361

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for a macromolecular complex in poor prognosis CLL that contains CD38, CD49d, CD44 and MMP-9

1 reference

https://pubmed.ncbi.nlm.nih.gov/21749361

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gene expression profiling of the functionally distinct human bone marrow stromal cell lines HS-5 and HS-27a

1 reference

https://pubmed.ncbi.nlm.nih.gov/21749361

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid immunotyping of B-cell non-Hodgkin's lymphomas by flow cytometry. A comparison with the standard frozen-section method

1 reference

https://pubmed.ncbi.nlm.nih.gov/21749361

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The affinity of integrin alpha(4)beta(1) governs lymphocyte migration

1 reference

https://pubmed.ncbi.nlm.nih.gov/21749361

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantification of cellular adhesion molecules on malignant B cells from non-Hodgkin's lymphoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/21749361

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of adhesion molecules in chronic B-cell lymphoproliferative disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/21749361

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rituximab (anti-CD20 monoclonal antibody) for the treatment of patients with relapsing or refractory aggressive lymphoma: a multicenter phase II study

1 reference

https://pubmed.ncbi.nlm.nih.gov/21749361

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rituximab anti-CD20 monoclonal antibody therapy in non-Hodgkin's lymphoma: safety and efficacy of re-treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/21749361

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1111/J.1365-2141.2011.08794.X

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