(Q28260352)

English

Anti-androgen flutamide suppresses hepatocellular carcinoma cell proliferation via the aryl hydrocarbon receptor mediated induction of transforming growth factor-β1

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scholarly article

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Anti-androgen flutamide suppresses hepatocellular carcinoma cell proliferation via the aryl hydrocarbon receptor mediated induction of transforming growth factor-β1 (English)

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hepatocellular carcinoma

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based on heuristic

inferred from title

author name string

D C Koch

1

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H S Jang

2

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E F O'Donnell

3

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S Punj

4

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P R Kopparapu

5

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W H Bisson

6

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N I Kerkvliet

7

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S K Kolluri

8

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language of work or name

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publication date

10 December 2015

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34

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50

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6092-104

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Cloning of the Ah-receptor cDNA reveals a distinctive ligand-activated transcription factor

1 reference

https://api.crossref.org/works/10.1038/ONC.2015.55

21 April 2017

Inducible, receptor-dependent protein-DNA interactions at a dioxin-responsive transcriptional enhancer

1 reference

https://api.crossref.org/works/10.1038/ONC.2015.55

21 April 2017

Ligand-dependent interaction of the aryl hydrocarbon receptor with a novel immunophilin homolog in vivo

1 reference

https://api.crossref.org/works/10.1038/ONC.2015.55

21 April 2017

Hepatitis B virus X-associated protein 2 is a subunit of the unliganded aryl hydrocarbon receptor core complex and exhibits transcriptional enhancer activity

1 reference

https://api.crossref.org/works/10.1038/ONC.2015.55

21 April 2017

The aryl hydrocarbon receptor complex and the control of gene expression

1 reference

https://api.crossref.org/works/10.1038/ONC.2015.55

21 April 2017

Immune system impairment and hepatic fibrosis in mice lacking the dioxin-binding Ah receptor

1 reference

https://api.crossref.org/works/10.1038/ONC.2015.55

21 April 2017

Characterization of a murine Ahr null allele: involvement of the Ah receptor in hepatic growth and development

1 reference

https://api.crossref.org/works/10.1038/ONC.2015.55

21 April 2017

Role of the aryl hydrocarbon receptor in cell cycle regulation

1 reference

https://api.crossref.org/works/10.1038/ONC.2015.55

21 April 2017

p27(Kip1) induction and inhibition of proliferation by the intracellular Ah receptor in developing thymus and hepatoma cells

1 reference

https://api.crossref.org/works/10.1038/ONC.2015.55

21 April 2017

A direct interaction between the aryl hydrocarbon receptor and retinoblastoma protein. Linking dioxin signaling to the cell cycle

1 reference

https://api.crossref.org/works/10.1038/ONC.2015.55

21 April 2017

The anti-inflammatory drug leflunomide is an agonist of the aryl hydrocarbon receptor

1 reference

https://api.crossref.org/works/10.1038/ONC.2015.55

21 April 2017

Master transcription factors determine cell-type-specific responses to TGF-β signaling

1 reference

https://api.crossref.org/works/10.1038/ONC.2015.55

21 April 2017

p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest

1 reference

https://api.crossref.org/works/10.1038/ONC.2015.55

21 April 2017

TGFbeta signaling in growth control, cancer, and heritable disorders

1 reference

https://api.crossref.org/works/10.1038/ONC.2015.55

21 April 2017

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.55

21 April 2017

p23, a simple protein with complex activities

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.55

21 January 2018

The aryl hydrocarbon receptor cross-talks with multiple signal transduction pathways

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.55

21 January 2018

Molecular biology of the Ah receptor and its role in carcinogenesis

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.55

21 January 2018

A proposed mechanism for the protective effect of dioxin against breast cancer

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.55

21 January 2018

2,3,7,8-Tetrachlorodibenzo-p-dioxin alters the differentiation of alloreactive CD8+ T cells toward a regulatory T cell phenotype by a mechanism that is dependent on aryl hydrocarbon receptor in CD4+ T cells

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.55

21 January 2018

Ah receptor: dioxin-mediated toxic responses as hints to deregulated physiologic functions

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.55

21 January 2018

N-acetylcysteine (NAC) diminishes the severity of PCB 126-induced fatty liver in male rodents

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.55

21 January 2018

Total serum testosterone and gonadotropins in workers exposed to dioxin

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.55

21 January 2018

Ah receptor in embryonic mouse palate and effects of TCDD on receptor expression.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.55

21 January 2018

Aryl-hydrocarbon receptor-deficient mice are resistant to 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced toxicity.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.55

21 January 2018

Expression and activity of aryl hydrocarbon receptors in development and cancer

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.55

21 January 2018

In utero exposure to dioxin causes neocortical dysgenesis through the actions of p27Kip1

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.55

21 January 2018

Complementation of Ah receptor deficiency in hepatoma cells: negative feedback regulation and cell cycle control by the Ah receptor

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.55

21 January 2018

The aryl hydrocarbon receptor inhibits prostate carcinogenesis in TRAMP mice.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.55

21 January 2018

The aryl hydrocarbon receptor functions as a tumor suppressor of liver carcinogenesis

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.55

21 January 2018

Activation of the aryl-hydrocarbon receptor inhibits invasive and metastatic features of human breast cancer cells and promotes breast cancer cell differentiation

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.55

21 January 2018

Antiestrogenic effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin are mediated by direct transcriptional interference with the liganded estrogen receptor. Cross-talk between aryl hydrocarbon- and estrogen-mediated signaling

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.55

21 January 2018

Modeling of the aryl hydrocarbon receptor (AhR) ligand binding domain and its utility in virtual ligand screening to predict new AhR ligands

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.55

21 January 2018

The aryl hydrocarbon receptor mediates leflunomide-induced growth inhibition of melanoma cells

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.55

21 January 2018

Benzimidazoisoquinolines: a new class of rapidly metabolized aryl hydrocarbon receptor (AhR) ligands that induce AhR-dependent Tregs and prevent murine graft-versus-host disease

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.55

21 January 2018

The aryl hydrocarbon receptor mediates raloxifene-induced apoptosis in estrogen receptor-negative hepatoma and breast cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.55

21 January 2018

Signaling through the Smad pathway by insulin-like growth factor-binding protein-3 in breast cancer cells. Relationship to transforming growth factor-beta 1 signaling.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.55

21 January 2018

Fitting a xenobiotic receptor into cell homeostasis: how the dioxin receptor interacts with TGFbeta signaling

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.55

21 January 2018

Ligand-independent regulation of transforming growth factor beta1 expression and cell cycle progression by the aryl hydrocarbon receptor.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.55

21 January 2018

Loss of dioxin-receptor expression accelerates wound healing in vivo by a mechanism involving TGFbeta.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.55

21 January 2018

Transforming growth factor-beta1 coregulates mRNA expression of aryl hydrocarbon receptor and cell-cycle-regulating genes in human cancer cell lines

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.55

21 January 2018

A Structural Switch between Agonist and Antagonist Bound Conformations for a Ligand-Optimized Model of the Human Aryl Hydrocarbon Receptor Ligand Binding Domain

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.55

21 January 2018

Aryl hydrocarbon receptor ligands in cancer: friend and foe.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.55

21 January 2018

Role of the aryl hydrocarbon receptor in carcinogenesis and potential as a drug target

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.55

21 January 2018

Aryl hydrocarbon receptor agonists induce microRNA-335 expression and inhibit lung metastasis of estrogen receptor negative breast cancer cells.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.55

21 January 2018

Aryl hydrocarbon receptor (AHR)-active pharmaceuticals are selective AHR modulators in MDA-MB-468 and BT474 breast cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.55

21 January 2018

Induction of cyp1a1 is a nonspecific biomarker of aryl hydrocarbon receptor activation: results of large scale screening of pharmaceuticals and toxicants in vivo and in vitro

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.55

31 March 2020

Endometriosis in rhesus monkeys (Macaca mulatta) following chronic exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.55

31 March 2020

Transforming growth factor-beta1 up-regulates p15, p21 and p27 and blocks cell cycling in G1 in human prostate epithelium

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.55

31 March 2020

Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-beta

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.55

31 March 2020

Novel target genes of the Ah (dioxin) receptor: transcriptional induction of N-myristoyltransferase 2

1 reference

https://pubmed.ncbi.nlm.nih.gov/25867062

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered cell cycle control at the G(2)/M phases in aryl hydrocarbon receptor-null embryo fibroblast.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25867062

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dioxin exposure and cancer risk: a 15-year mortality study after the "Seveso accident".

1 reference

https://pubmed.ncbi.nlm.nih.gov/25867062

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of the Ah receptor with the 90-kDa heat shock protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/25867062

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mapping the 90 kDa heat shock protein binding region of the Ah receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/25867062

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efficacious chemoprevention of primary prostate cancer by flutamide in an autochthonous transgenic model

1 reference

https://pubmed.ncbi.nlm.nih.gov/25867062

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/ONC.2015.55

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Dimensions Publication ID

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release_t2swdrhgqrg4dble2wfz6evuya

1 reference

https://api.fatcat.wiki/v0/release/t2swdrhgqrg4dble2wfz6evuya

24 November 2022

based on heuristic

mapped directly with Wikidata item

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Springer Nature article ID

10.1038/onc.2015.55

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