(Q28262008)

1

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Cynthia Cowdrey

4

Cynthia Cowdrey

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Stanley B. Prusiner

8

Stanley B Prusiner

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Stephen J DeArmond

6

Stephen J DeArmond

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Fred E Cohen

7

Fred E Cohen

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author name string

Kirk Hansen

2

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Jialing Liu

3

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Jian Yang

5

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Michael A Baldwin

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

9

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language of work or name

English

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publication date

June 2004

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published in

Nature Biotechnology

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volume

22

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issue

6

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page(s)

724-31

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cites work

1 reference

Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and betaAPP processing

21 April 2017

1 reference

The presenilin 1 protein is a component of a high molecular weight intracellular complex that contains beta-catenin

21 April 2017

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Amyloidogenic processing of the Alzheimer beta-amyloid precursor protein depends on lipid rafts

21 April 2017

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Identification of candidate proteins binding to prion protein

21 April 2017

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Functionally different GPI proteins are organized in different domains on the neuronal surface

21 April 2017

1 reference

Caveolae, plasma membrane microdomains for alpha-secretase-mediated processing of the amyloid precursor protein

21 April 2017

1 reference

Differential Recruitment of Kv1.4 and Kv4.2 to Lipid Rafts by PSD-95

21 April 2017

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21 April 2017

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The post-genomic era of interactive proteomics: facts and perspectives

21 April 2017

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Drug discovery of the future: the implications of the human genome project

21 January 2018

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Alzheimer disease gamma-secretase: a complex story of GxGD-type presenilin proteases

21 January 2018

1 reference

Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene

21 January 2018

1 reference

APH-1 is a multipass membrane protein essential for the Notch signaling pathway in Caenorhabditis elegans embryos

21 January 2018

1 reference

aph-1 and pen-2 are required for Notch pathway signaling, gamma-secretase cleavage of betaAPP, and presenilin protein accumulation

21 January 2018

1 reference

Glycolipid-anchored proteins in neuroblastoma cells form detergent-resistant complexes without caveolin

21 January 2018

1 reference

Characterization of detergent-insoluble complexes containing the cellular prion protein and its scrapie isoform.

21 January 2018

1 reference

Cholesterol depletion and modification of COOH-terminal targeting sequence of the prion protein inhibit formation of the scrapie isoform

21 January 2018

1 reference

Subcellular colocalization of the cellular and scrapie prion proteins in caveolae-like membranous domains

21 January 2018

1 reference

COOH-terminal sequence of the cellular prion protein directs subcellular trafficking and controls conversion into the scrapie isoform

21 January 2018

1 reference

Soluble dimeric prion protein binds PrP(Sc) in vivo and antagonizes prion disease.

21 January 2018

1 reference

Characterizing transcription factor binding sites using formaldehyde crosslinking and immunoprecipitation

21 January 2018

1 reference

Formaldehyde cross-linking for studying nucleosomal dynamics

21 January 2018

1 reference

Analysis of chromatin structure by in vivo formaldehyde cross-linking.

21 January 2018

1 reference

Binding of neural cell adhesion molecules (N-CAMs) to the cellular prion protein

21 January 2018

1 reference

Reconstitution of gamma-secretase activity

21 January 2018

1 reference

Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein

21 January 2018

1 reference

Allosteric modulation of AMPA-type glutamate receptors increases activity of the promoter for the neural cell adhesion molecule, N-CAM

21 January 2018

1 reference

Prion protein as trans-interacting partner for neurons is involved in neurite outgrowth and neuronal survival

21 January 2018

1 reference

Lipid rafts mediate the interaction between myelin-associated glycoprotein (MAG) on myelin and MAG-receptors on neurons

21 January 2018

1 reference

Hyaluronic acid induces survival and proliferation of human myeloma cells through an interleukin-6-mediated pathway involving the phosphorylation of retinoblastoma protein

21 January 2018

1 reference

The regions of the Fe65 protein homologous to the phosphotyrosine interaction/phosphotyrosine binding domain of Shc bind the intracellular domain of the Alzheimer's amyloid precursor protein

21 January 2018

1 reference

The F3 Neuronal Glycosylphosphatidylinositol‐Linked Molecule Is Localized to Glycolipid‐Enriched Membrane Subdomains and Interacts with L1 and Fyn Kinase in Cerebellum

21 January 2018

1 reference

Lipid rafts: elusive or illusive?

21 January 2018

1 reference

Sorting of GPI-anchored proteins to glycolipid-enriched membrane subdomains during transport to the apical cell surface

21 January 2018

1 reference

Extensive temporally regulated reorganization of the lipid raft proteome following T-cell antigen receptor triggering

21 January 2018

1 reference

Unbiased quantitative proteomics of lipid rafts reveals high specificity for signaling factors

21 January 2018

1 reference

Axonal amyloid precursor protein expressed by neurons in vitro is present in a membrane fraction with caveolae-like properties.

21 January 2018

1 reference

Local actin polymerization and dynamin recruitment in SV40-induced internalization of caveolae

21 January 2018

1 reference

Caveolae/raft-dependent endocytosis

21 January 2018

1 reference

Identification of two prion protein regions that modify scrapie incubation time

21 January 2018

1 reference

Role of accurate mass measurement (+/- 10 ppm) in protein identification strategies employing MS or MS/MS and database searching.

21 January 2018

1 reference

Alzheimer's disease: genes, proteins, and therapy

21 January 2018

1 reference

7 January 2021

Analysis of in vivo nucleosome positions by determination of nucleosome-linker boundaries in crosslinked chromatin

1 reference

7 January 2021

Differential extraction of proteins from paraformaldehyde-fixed cells: lessons from synaptophysin and other membrane proteins

1 reference

7 January 2021

The Chaperone Protein BiP Binds to a Mutant Prion Protein and Mediates Its Degradation by the Proteasome

1 reference

7 January 2021

Mass spectrometric characterization of proteins extracted from Jurkat T cell detergent-resistant membrane domains

1 reference

7 January 2021