(Q28268066)

A multifactor complex of eukaryotic initiation factors, eIF1, eIF2, eIF3, eIF5, and initiator tRNA(Met) is an important translation initiation intermediate in vivo

21 April 2017

1 reference

Efficient incorporation of eukaryotic initiation factor 1 into the multifactor complex is critical for formation of functional ribosomal preinitiation complexes in vivo

21 April 2017

1 reference

Domains of eIF1A that mediate binding to eIF2, eIF3 and eIF5B and promote ternary complex recruitment in vivo

21 April 2017

1 reference

Multiple roles for the C-terminal domain of eIF5 in translation initiation complex assembly and GTPase activation

21 April 2017

1 reference

Development and characterization of a reconstituted yeast translation initiation system.

21 April 2017

1 reference

Mammalian translation initiation factor eIF1 functions with eIF1A and eIF3 in the formation of a stable 40 S preinitiation complex

21 April 2017

1 reference

Crystal structure of the eukaryotic 40S ribosomal subunit in complex with initiation factor 1

21 April 2017

1 reference

Eukaryotic translation initiation factor 5 functions as a GTPase-activating protein

21 April 2017

1 reference

Ribosomal position and contacts of mRNA in eukaryotic translation initiation complexes

21 April 2017

1 reference

Eukaryotic translation initiation factor 3 (eIF3) and eIF2 can promote mRNA binding to 40S subunits independently of eIF4G in yeast

21 April 2017

1 reference

Rpg1p/Tif32p, a subunit of translation initiation factor 3, interacts with actin-associated protein Sla2p.

21 April 2017

1 reference

The eukaryotic translation initiation factors eIF1 and eIF1A induce an open conformation of the 40S ribosome

21 April 2017

1 reference

A conformational change in the eukaryotic translation preinitiation complex and release of eIF1 signal recognition of the start codon

21 April 2017

1 reference

Multiple elements in the eIF4G1 N-terminus promote assembly of eIF4G1•PABP mRNPs in vivo.

21 April 2017

1 reference

Mammalian poly(A)-binding protein is a eukaryotic translation initiation factor, which acts via multiple mechanisms

21 April 2017

1 reference

Functional analysis of individual binding activities of the scaffold protein eIF4G

21 April 2017

1 reference

eIF4GI links nutrient sensing by mTOR to cell proliferation and inhibition of autophagy

21 April 2017

1 reference

ATP hydrolysis is required for DEAD-box protein recycling but not for duplex unwinding

21 April 2017

1 reference

Structural basis for the enhancement of eIF4A helicase activity by eIF4G.

21 April 2017

1 reference

Topology and regulation of the human eIF4A/4G/4H helicase complex in translation initiation

21 April 2017

1 reference

The RNA recognition motif of yeast translation initiation factor Tif3/eIF4B is required but not sufficient for RNA strand-exchange and translational activity

21 April 2017

1 reference

The RNA recognition motif of eukaryotic translation initiation factor 3g (eIF3g) is required for resumption of scanning of posttermination ribosomes for reinitiation on GCN4 and together with eIF3i stimulates linear scanning

21 April 2017

1 reference

Untranslated regions of mRNAs

21 April 2017

1 reference

Functional elements in initiation factors 1, 1A, and 2β discriminate against poor AUG context and non-AUG start codons

21 April 2017

1 reference

Dynamics and processivity of 40S ribosome scanning on mRNA in yeast

21 April 2017

1 reference

Eukaryotic initiation factor (eIF) 1 carries two distinct eIF5-binding faces important for multifactor assembly and AUG selection

21 April 2017

1 reference

Stringency of start codon selection modulates autoregulation of translation initiation factor eIF5

21 April 2017

1 reference

Communication between eukaryotic translation initiation factors 5 and 1A within the ribosomal pre-initiation complex plays a role in start site selection

21 April 2017

1 reference

Structural analysis of an eIF3 subcomplex reveals conserved interactions required for a stable and proper translation pre-initiation complex assembly

21 April 2017

1 reference

The joining of ribosomal subunits in eukaryotes requires eIF5B.

21 April 2017

1 reference

Interaction between eukaryotic initiation factors 1A and 5B is required for efficient ribosomal subunit joining.

21 April 2017

1 reference

Uncoupling of initiation factor eIF5B/IF2 GTPase and translational activities by mutations that lower ribosome affinity

21 April 2017

1 reference

Mapping the binding interface between human eukaryotic initiation factors 1A and 5B: a new interaction between old partners

21 April 2017

1 reference

The structure of the eukaryotic ribosome at 3.0 Å resolution

21 April 2017

1 reference

The mechanism of eukaryotic translation initiation and principles of its regulation

21 April 2017

1 reference

Structural basis for RNA unwinding by the DEAD-box protein Drosophila Vasa

21 April 2017

1 reference

Molecular mechanism of scanning and start codon selection in eukaryotes

21 April 2017

1 reference

Eukaryotic initiator tRNA: finely tuned and ready for action

21 January 2018

1 reference

GTP-dependent recognition of the methionine moiety on initiator tRNA by translation factor eIF2.

21 January 2018

1 reference

Initiation factor eIF2γ promotes eIF2-GTP-Met-tRNAi(Met) ternary complex binding to the 40S ribosome

21 January 2018

1 reference

Specific functional interactions of nucleotides at key -3 and +4 positions flanking the initiation codon with components of the mammalian 48S translation initiation complex

21 January 2018

1 reference

Binding of eukaryotic initiation factor 3 to ribosomal 40S subunits and its role in ribosomal dissociation and anti-association

21 January 2018

1 reference

Position of eukaryotic initiation factor eIF1 on the 40S ribosomal subunit determined by directed hydroxyl radical probing

21 January 2018

1 reference

Position of eukaryotic translation initiation factor eIF1A on the 40S ribosomal subunit mapped by directed hydroxyl radical probing.

21 January 2018

1 reference

Direct binding of translation initiation factor eIF2gamma-G domain to its GTPase-activating and GDP-GTP exchange factors eIF5 and eIF2B epsilon

21 January 2018

1 reference

Eukaryotic translation initiation factor 5 (eIF5) acts as a classical GTPase-activator protein.

21 January 2018

1 reference

Conserved bipartite motifs in yeast eIF5 and eIF2Bepsilon, GTPase-activating and GDP-GTP exchange factors in translation initiation, mediate binding to their common substrate eIF2.

21 January 2018

1 reference

The eukaryotic initiation factor (eIF) 5 HEAT domain mediates multifactor assembly and scanning with distinct interfaces to eIF1, eIF2, eIF3, and eIF4G

21 January 2018

1 reference

Structural roles for human translation factor eIF3 in initiation of protein synthesis

21 January 2018

1 reference

The yeast eIF3 subunits TIF32/a, NIP1/c, and eIF5 make critical connections with the 40S ribosome in vivo.

21 January 2018

1 reference

The C-terminal region of eukaryotic translation initiation factor 3a (eIF3a) promotes mRNA recruitment, scanning, and, together with eIF3j and the eIF3b RNA recognition motif, selection of AUG start codons.

21 January 2018

1 reference

The human translation initiation multi-factor complex promotes methionyl-tRNAi binding to the 40S ribosomal subunit

21 January 2018

1 reference

Direct eIF2-eIF3 contact in the multifactor complex is important for translation initiation in vivo

21 January 2018

1 reference

Functions of eIF3 downstream of 48S assembly impact AUG recognition and GCN4 translational control

21 January 2018

1 reference

Interactions of eukaryotic translation initiation factor 3 (eIF3) subunit NIP1/c with eIF1 and eIF5 promote preinitiation complex assembly and regulate start codon selection

21 January 2018

1 reference

Eukaryotic translation initiation factor 5 is critical for integrity of the scanning preinitiation complex and accurate control of GCN4 translation.

21 January 2018

1 reference

Two subcellular localizations of eIF3 p170 and its interaction with membrane-bound microfilaments: implications for alternative functions of p170.

21 January 2018

1 reference

Communication between eukaryotic translation initiation factors 1 and 1A on the yeast small ribosomal subunit

21 January 2018

1 reference

Eukaryotic ribosomes require initiation factors 1 and 1A to locate initiation codons

21 January 2018

1 reference

Regulatory elements in eIF1A control the fidelity of start codon selection by modulating tRNA(i)(Met) binding to the ribosome

21 January 2018

1 reference

N- and C-terminal residues of eIF1A have opposing effects on the fidelity of start codon selection

21 January 2018

1 reference

Distinct functions of eukaryotic translation initiation factors eIF1A and eIF3 in the formation of the 40 S ribosomal preinitiation complex.

21 January 2018

1 reference

A novel role of the mammalian GSPT/eRF3 associating with poly(A)-binding protein in Cap/Poly(A)-dependent translation

21 January 2018

1 reference

Intrinsic RNA binding by the eukaryotic initiation factor 4F depends on a minimal RNA length but not on the m7G cap.

21 January 2018

1 reference

The 5'-7-methylguanosine cap on eukaryotic mRNAs serves both to stimulate canonical translation initiation and to block an alternative pathway.

21 January 2018

1 reference

Requirement of RNA binding of mammalian eukaryotic translation initiation factor 4GI (eIF4GI) for efficient interaction of eIF4E with the mRNA cap.

21 January 2018

1 reference

Translation initiation factor eIF4G mediates in vitro poly(A) tail-dependent translation

21 January 2018

1 reference

General RNA-binding proteins have a function in poly(A)-binding protein-dependent translation

21 January 2018

1 reference

Depletion of eIF4G from yeast cells narrows the range of translational efficiencies genome-wide

21 January 2018

1 reference

Evidence for variation in the optimal translation initiation complex: plant eIF4B, eIF4F, and eIF(iso)4F differentially promote translation of mRNAs.

21 January 2018

1 reference

The DEAD box protein eIF4A. 1. A minimal kinetic and thermodynamic framework reveals coupled binding of RNA and nucleotide

21 January 2018

1 reference

eIF4G stimulates the activity of the DEAD box protein eIF4A by a conformational guidance mechanism

21 January 2018

1 reference

Modulation of the helicase activity of eIF4A by eIF4B, eIF4H, and eIF4F.

21 January 2018

1 reference

Interactions between eIF4AI and its accessory factors eIF4B and eIF4H

21 January 2018

1 reference

Wheat germ translation initiation factor eIF4B affects eIF4A and eIFiso4F helicase activity by increasing the ATP binding affinity of eIF4A.

21 January 2018

1 reference

Translation initiation factor 4B homodimerization, RNA binding, and interaction with Poly(A)-binding protein are enhanced by zinc

21 January 2018

1 reference

Duplex unwinding and ATPase activities of the DEAD-box helicase eIF4A are coupled by eIF4G and eIF4B

21 January 2018

1 reference

Synergistic activation of eIF4A by eIF4B and eIF4G.

21 January 2018

1 reference

Translation initiation factor eIF4G-1 binds to eIF3 through the eIF3e subunit

21 January 2018

1 reference

A region rich in aspartic acid, arginine, tyrosine, and glycine (DRYG) mediates eukaryotic initiation factor 4B (eIF4B) self-association and interaction with eIF3

21 January 2018

1 reference

Assembly of 48S translation initiation complexes from purified components with mRNAs that have some base pairing within their 5' untranslated regions.

21 January 2018

1 reference

eIF3: a versatile scaffold for translation initiation complexes

21 January 2018

1 reference

Interaction of the RNP1 motif in PRT1 with HCR1 promotes 40S binding of eukaryotic initiation factor 3 in yeast

21 January 2018

1 reference

Release of initiation factors from 48S complexes during ribosomal subunit joining and the link between establishment of codon-anticodon base-pairing and hydrolysis of eIF2-bound GTP.

21 January 2018

1 reference

The indispensable N-terminal half of eIF3j/HCR1 cooperates with its structurally conserved binding partner eIF3b/PRT1-RRM and with eIF1A in stringent AUG selection

21 January 2018

1 reference

Initiation context modulates autoregulation of eukaryotic translation initiation factor 1 (eIF1)

21 January 2018

1 reference

Unidirectional constant rate motion of the ribosomal scanning particle during eukaryotic translation initiation

21 January 2018

1 reference

The roles of individual eukaryotic translation initiation factors in ribosomal scanning and initiation codon selection

21 January 2018

1 reference

Characterization of a novel RNA-binding region of eIF4GI critical for ribosomal scanning

21 January 2018

1 reference

The eukaryotic initiation factor (eIF) 4G HEAT domain promotes translation re-initiation in yeast both dependent on and independent of eIF4A mRNA helicase

21 January 2018

1 reference

Cap-dependent eukaryotic initiation factor-mRNA interactions probed by cross-linking

21 January 2018

1 reference

Translation initiation on mammalian mRNAs with structured 5'UTRs requires DExH-box protein DHX29.

21 January 2018

1 reference

Bypassing of stems versus linear base-by-base inspection of mammalian mRNAs during ribosomal scanning.

21 January 2018

1 reference

How does a scanning ribosomal particle move along the 5'-untranslated region of eukaryotic mRNA? Brownian Ratchet model

21 January 2018

1 reference

Pi release from eIF2, not GTP hydrolysis, is the step controlled by start-site selection during eukaryotic translation initiation

21 January 2018

1 reference

Dissociation of eIF1 from the 40S ribosomal subunit is a key step in start codon selection in vivo

21 January 2018

1 reference

eIF1 controls multiple steps in start codon recognition during eukaryotic translation initiation

21 January 2018

1 reference

Kinetic analysis of late steps of eukaryotic translation initiation

21 January 2018

1 reference

eIF3a cooperates with sequences 5' of uORF1 to promote resumption of scanning by post-termination ribosomes for reinitiation on GCN4 mRNA.

21 January 2018

1 reference

The mechanism of an exceptional case of reinitiation after translation of a long ORF reveals why such events do not generally occur in mammalian mRNA translation

21 January 2018

1 reference

A quantitative model for mRNA translation in Saccharomyces cerevisiae

21 January 2018

1 reference

Analysing GCN4 translational control in yeast by stochastic chemical kinetics modelling and simulation

21 January 2018

1 reference

tRNA binding properties of eukaryotic translation initiation factor 2 from Encephalitozoon cuniculi

21 January 2018

1 reference

Intracellular translation initiation factor levels in Saccharomyces cerevisiae and their role in cap-complex function

31 March 2020

1 reference

Specific domains in yeast translation initiation factor eIF4G strongly bias RNA unwinding activity of the eIF4F complex toward duplexes with 5'-overhangs

31 March 2020

1 reference

The Saccharomyces cerevisiae translation initiation factor Tif3 and its mammalian homologue, eIF-4B, have RNA annealing activity

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22664984

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Rpg1p, the subunit of the Saccharomyces cerevisiae eIF3 core complex, is a microtubule-interacting protein

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22664984

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NSMB.2303

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017

PubMed publication ID

22664984

1 reference

Consolidated OpenCitations Corpus – April 2017