(Q35534370)

8 August 2017

Initiation factor eIF2γ promotes eIF2-GTP-Met-tRNAi(Met) ternary complex binding to the 40S ribosome (English)

1 reference

8 August 2017

5

Jon R Lorsch

0 references

Thomas Dever

6

object named as

Thomas E Dever

1 reference

8 August 2017

Byung-Sik Shin

1

1 reference

8 August 2017

Joo-Ran Kim

2

1 reference

8 August 2017

Sarah E Walker

3

1 reference

8 August 2017

Jinsheng Dong

4

1 reference

8 August 2017

language of work or name

1 reference

16 October 2011

1 reference

Nature Structural & Molecular Biology

8 August 2017

1 reference

8 August 2017

18

1 reference

8 August 2017

11

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8 August 2017

1227-1234

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https://scigraph.springernature.com/pub.10.1038/nsmb.2133

8 August 2017

0 references

cites work

Crystal structure of the eukaryotic 40S ribosomal subunit in complex with initiation factor 1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210414

Crystal structure of the eukaryotic ribosome

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210414

Regulatory elements in eIF1A control the fidelity of start codon selection by modulating tRNA(i)(Met) binding to the ribosome

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210414

The Crystal Structure of the Ribosome Bound to EF-Tu and Aminoacyl-tRNA

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210414

The Structure of the Ribosome with Elongation Factor G Trapped in the Posttranslocational State

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210414

Regulation of translation initiation in eukaryotes: mechanisms and biological targets

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210414

Structure of the 30S translation initiation complex.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210414

Crystal structure of the intact archaeal translation initiation factor 2 demonstrates very high conformational flexibility in the alpha- and beta-subunits

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210414

Structure of an archaeal heterotrimeric initiation factor 2 reveals a nucleotide state between the GTP and the GDP states

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210414

Position of eukaryotic initiation factor eIF5B on the 80S ribosome mapped by directed hydroxyl radical probing

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210414

The 51-63 base pair of tRNA confers specificity for binding by EF-Tu

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210414

The eukaryotic translation initiation factors eIF1 and eIF1A induce an open conformation of the 40S ribosome

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210414

Structural basis for interaction of the ribosome with the switch regions of GTP-bound elongation factors

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210414

N- and C-terminal residues of eIF1A have opposing effects on the fidelity of start codon selection

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210414

Structure of the 70S ribosome complexed with mRNA and tRNA

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210414

Structure of archaeal translational initiation factor 2 betagamma-GDP reveals significant conformational change of the beta-subunit and switch 1 region

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210414

Specific functional interactions of nucleotides at key -3 and +4 positions flanking the initiation codon with components of the mammalian 48S translation initiation complex

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210414

Translational regulation of GCN4 and the general amino acid control of yeast

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210414

X-ray structure of translation initiation factor eIF2gamma: implications for tRNA and eIF2alpha binding

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210414

Position of eukaryotic initiation factor eIF1 on the 40S ribosomal subunit determined by directed hydroxyl radical probing

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210414

Uniform binding of aminoacyl-tRNAs to elongation factor Tu by thermodynamic compensation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210414

Multiple roles for the C-terminal domain of eIF5 in translation initiation complex assembly and GTPase activation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210414

Crystal structure of an initiation factor bound to the 30S ribosomal subunit

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210414

The eIF1A solution structure reveals a large RNA-binding surface important for scanning function

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210414

Visualization of elongation factor G on the Escherichia coli 70S ribosome: the mechanism of translocation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210414

Ligand interactions with eukaryotic translation initiation factor 2: role of the gamma-subunit

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210414

Rit1, a tRNA backbone-modifying enzyme that mediates initiator and elongator tRNA discrimination

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210414

Mutations in GCD11, the structural gene for eIF-2 gamma in yeast, alter translational regulation of GCN4 and the selection of the start site for protein synthesis.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210414

Crystal structure of the ternary complex of Phe-tRNAPhe, EF-Tu, and a GTP analog

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210414

A hierarchy of trans-acting factors modulates translation of an activator of amino acid biosynthetic genes in Saccharomyces cerevisiae

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210414

Multiple GCD genes required for repression of GCN4, a transcriptional activator of amino acid biosynthetic genes in Saccharomyces cerevisiae

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210414

Translational regulation of expression of the bacteriophage T4 lysozyme gene

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210414

The 3 A crystal structure of yeast initiator tRNA: functional implications in initiator/elongator discrimination

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210414

The Mechanism for Activation of GTP Hydrolysis on the Ribosome

27 July 2018

1 reference

A conformational change in the eukaryotic translation preinitiation complex and release of eIF1 signal recognition of the start codon

21 January 2018

1 reference

Position of eukaryotic translation initiation factor eIF1A on the 40S ribosomal subunit mapped by directed hydroxyl radical probing.

21 January 2018

1 reference

The large subunit of initiation factor aIF2 is a close structural homologue of elongation factors.

21 January 2018

1 reference

Structural switch of the gamma subunit in an archaeal aIF2 alpha gamma heterodimer.

21 January 2018

1 reference

Directed mutagenesis identifies amino acid residues involved in elongation factor Tu binding to yeast Phe-tRNAPhe

21 January 2018

1 reference

Genetic identification of yeast 18S rRNA residues required for efficient recruitment of initiator tRNA(Met) and AUG selection

21 January 2018

1 reference

rRNA suppressor of a eukaryotic translation initiation factor 5B/initiation factor 2 mutant reveals a binding site for translational GTPases on the small ribosomal subunit.

21 January 2018

1 reference

Functional molecular mapping of archaeal translation initiation factor 2.

21 January 2018

1 reference

The beta subunit of eukaryotic translation initiation factor 2 binds mRNA through the lysine repeats and a region comprising the C2-C2 motif

21 January 2018

1 reference

The yeast initiator tRNAMet can act as an elongator tRNA(Met) in vivo.

21 January 2018

1 reference

The affinity of elongation factor Tu for an aminoacyl-tRNA is modulated by the esterified amino acid

21 January 2018

1 reference

GTP-dependent recognition of the methionine moiety on initiator tRNA by translation factor eIF2.

21 January 2018

1 reference

A computational screen for methylation guide snoRNAs in yeast

21 January 2018

1 reference

Reconstitution of yeast translation initiation.

21 January 2018

1 reference

Directed hydroxyl radical probing of RNA from iron(II) tethered to proteins in ribonucleoprotein complexes

21 January 2018

1 reference

31 March 2020

Identifiers

DOI

10.1038/NSMB.2133

1 reference

Dimensions Publication ID

8 August 2017

0 references

1 reference

8 August 2017

1 reference