(Q28268615)

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The tumour-suppressor Scribble dictates cell polarity during directed epithelial migration: regulation of Rho GTPase recruitment to the leading edge

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The tumour-suppressor Scribble dictates cell polarity during directed epithelial migration: regulation of Rho GTPase recruitment to the leading edge (English)

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7

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S M Russell

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author name string

L E Dow

1

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J S Kauffman

2

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J Caddy

3

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K Zarbalis

4

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A S Peterson

5

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S M Jane

6

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P O Humbert

8

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language of work or name

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publication date

5 April 2007

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26

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2272-82

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16

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Mammalian Scribble forms a tight complex with the betaPIX exchange factor

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210016

21 January 2018

Epithelial polarity and proliferation control: links from the Drosophila neoplastic tumor suppressors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210016

21 January 2018

Localization of apical epithelial determinants by the basolateral PDZ protein Scribble

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210016

21 January 2018

Integrated activity of PDZ protein complexes regulates epithelial polarity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210016

21 January 2018

scribble mutants cooperate with oncogenic Ras or Notch to cause neoplastic overgrowth in Drosophila

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210016

21 January 2018

Stable suppression of tumorigenicity by virus-mediated RNA interference

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210016

21 January 2018

Cdc42 controls the polarity of the actin and microtubule cytoskeletons through two distinct signal transduction pathways.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210016

21 January 2018

Differential expression of the human homologue of drosophila discs large oncosuppressor in histologic samples from human papillomavirus-associated lesions as a marker for progression to malignancy.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210016

21 January 2018

Par-3 controls tight junction assembly through the Rac exchange factor Tiam1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210016

21 January 2018

Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210016

21 January 2018

hScrib is a functional homologue of the Drosophila tumour suppressor Scribble

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210016

21 January 2018

Integrin-mediated activation of Cdc42 controls cell polarity in migrating astrocytes through PKCzeta

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210016

21 January 2018

Cdc42 regulates GSK-3beta and adenomatous polyposis coli to control cell polarity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210016

21 January 2018

Cdc42 and Par6-PKCzeta regulate the spatially localized association of Dlg1 and APC to control cell polarization.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210016

21 January 2018

Human discs large and scrib are localized at the same regions in colon mucosa and changes in their expression patterns are correlated with loss of tissue architecture during malignant progression.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210016

21 January 2018

Nuclear movement regulated by Cdc42, MRCK, myosin, and actin flow establishes MTOC polarization in migrating cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210016

21 January 2018

Dlg, Scribble and Lgl in cell polarity, cell proliferation and cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210016

21 January 2018

The Scribble and Par complexes in polarity and migration: friends or foes?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210016

21 January 2018

LET-413 is a basolateral protein required for the assembly of adherens junctions in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210016

21 January 2018

Basolateral targeting by leucine-rich repeat domains in epithelial cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210016

21 January 2018

Differential expression of human Dlg in cervical intraepithelial neoplasias

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210016

21 January 2018

HPV E6 specifically targets different cellular pools of its PDZ domain-containing tumour suppressor substrates for proteasome-mediated degradation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210016

21 January 2018

Disruption of scribble (Scrb1) causes severe neural tube defects in the circletail mouse

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210016

21 January 2018

Human scribble (Vartul) is targeted for ubiquitin-mediated degradation by the high-risk papillomavirus E6 proteins and the E6AP ubiquitin-protein ligase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210016

21 January 2018

Analysis of the expression and localisation of a LAP protein, human scribble, in the normal and neoplastic epithelium of uterine cervix

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210016

21 January 2018

Junctional recruitment of mammalian Scribble relies on E-cadherin engagement

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210016

21 January 2018

An alpha4 integrin-paxillin-Arf-GAP complex restricts Rac activation to the leading edge of migrating cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210016

21 January 2018

Rho GTPases control polarity, protrusion, and adhesion during cell movement

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210016

21 January 2018

Regulation of the polarity protein Par6 by TGFbeta receptors controls epithelial cell plasticity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210016

21 January 2018

A Genetic Screen in Drosophila for Metastatic Behavior

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210016

21 January 2018

Interaction with basement membrane serves to rapidly distinguish growth and differentiation pattern of normal and malignant human breast epithelial cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210016

21 January 2018

Requirement for Par-6 and Bazooka in Drosophila border cell migration

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210016

21 January 2018

The mammalian Scribble polarity protein regulates epithelial cell adhesion and migration through E-cadherin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210016

21 January 2018

H-Ras-specific activation of Rac-MKK3/6-p38 pathway: its critical role in invasion and migration of breast epithelial cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210016

21 January 2018

The hScrib/Dlg apico-basal control complex is differentially targeted by HPV-16 and HPV-18 E6 proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210016

21 January 2018

A homolog of Drosophila grainy head is essential for epidermal integrity in mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210016

21 January 2018

Dual roles of zygotic and maternal Scribble1 in neural migration and convergent extension movements in zebrafish embryos

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210016

21 January 2018

Interaction with IQGAP1 links APC to Rac1, Cdc42, and actin filaments during cell polarization and migration

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210016

21 January 2018

Changes in expression of the human homologue of the Drosophila discs large tumour suppressor protein in high-grade premalignant cervical neoplasias

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210016

21 January 2018

A focused and efficient genetic screening strategy in the mouse: identification of mutations that disrupt cortical development

1 reference

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21 January 2018

c-Jun regulates eyelid closure and skin tumor development through EGFR signaling

1 reference

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21 January 2018

A Network of PDZ-Containing Proteins Regulates T Cell Polarity and Morphology during Migration and Immunological Synapse Formation

1 reference

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7 January 2021

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A study of wound healing in the E11.5 mouse embryo by light and electron microscopy

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7 January 2021

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HB-EGF promotes epithelial cell migration in eyelid development

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7 January 2021

based on heuristic

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10.1038/SJ.ONC.1210016

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Springer Nature article ID

10.1038/sj.onc.1210016

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