(Q28268940)

Presenilin function and gamma-secretase activity

21 January 2018

1 reference

Increased vulnerability of hippocampal neurons from presenilin-1 mutant knock-in mice to amyloid beta-peptide toxicity: central roles of superoxide production and caspase activation.

21 January 2018

1 reference

The glp-1 locus and cellular interactions in early C. elegans embryos

21 January 2018

1 reference

glp-1 is required in the germ line for regulation of the decision between mitosis and meiosis in C. elegans

21 January 2018

1 reference

Reverse genetic analysis of Caenorhabditis elegans presenilins reveals redundant but unequal roles for sel-12 and hop-1 in Notch-pathway signaling

21 January 2018

1 reference

The love-hate relationship between Ras and Notch.

21 January 2018

1 reference

The Caenorhabditis elegans presenilin sel-12 is required for mesodermal patterning and muscle function.

21 January 2018

1 reference

The SEL-12 presenilin mediates induction of the Caenorhabditis elegans uterine pi cell fate

21 January 2018

1 reference

The lin-12 locus specifies cell fates in Caenorhabditis elegans

21 January 2018

1 reference

Loss of spr-5 bypasses the requirement for the C.elegans presenilin sel-12 by derepressing hop-1.

21 January 2018

1 reference

Presenilin is required for proper morphology and function of neurons in C. elegans

21 January 2018

1 reference

aph-1 and pen-2 are required for Notch pathway signaling, gamma-secretase cleavage of betaAPP, and presenilin protein accumulation

21 January 2018

1 reference

Two suppressors of sel-12 encode C2H2 zinc-finger proteins that regulate presenilin transcription in Caenorhabditis elegans.

21 January 2018

1 reference

Suppressors of the egg-laying defective phenotype of sel-12 presenilin mutants implicate the CoREST corepressor complex in LIN-12/Notch signaling in C. elegans

21 January 2018

1 reference

Regulation of neuronal traits by a novel transcriptional complex

21 January 2018

1 reference

REST and its corepressors mediate plasticity of neuronal gene chromatin throughout neurogenesis.

21 January 2018

1 reference

CoREST: a functional corepressor required for regulation of neural-specific gene expression

21 January 2018

1 reference

Histone demethylation mediated by the nuclear amine oxidase homolog LSD1

21 January 2018

1 reference

Regulation of LSD1 histone demethylase activity by its associated factors

21 January 2018

1 reference

Reversing histone methylation

21 January 2018

1 reference