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Avian defensins

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Europe PubMed Central

21 May 2022

Avian defensins (English)

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infectious disease

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author name string

Albert van Dijk

1

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Edwin J A Veldhuizen

2

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Henk P Haagsman

3

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language of work or name

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publication date

15 July 2008

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21 May 2022

Veterinary Immunology and Immunopathology

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21 May 2022

124

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1-2

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1-18

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Neutrophil defensins enhance lung epithelial wound closure and mucin gene expression in vitro

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Molecular and functional characterization of bovine beta-defensin-1.

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Secretion of microbicidal alpha-defensins by intestinal Paneth cells in response to bacteria

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Inter-population variability of DEFA3 gene absence: correlation with haplotype structure and population variability

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Development and adaptations of innate immunity in the gastrointestinal tract of the newly hatched chick

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Induction of autolysis of staphylococci by the basic peptide antibiotics Pep 5 and nisin and their influence on the activity of autolytic enzymes

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Characterization of beta-defensin prepropeptide mRNA from chicken and turkey bone marrow

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Genetics of resistance to Salmonella typhimurium in newly hatched chicks

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Structure-activity relationships in defensin dimers: a novel link between beta-defensin tertiary structure and antimicrobial activity

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Identification of defensin-1, defensin-2, and CAP37/azurocidin as T-cell chemoattractant proteins released from interleukin-8-stimulated neutrophils

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Localized antimicrobial peptide expression in human gingiva

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Detection of beta-defensins secreted by human oral epithelial cells.

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The mammalian ionic environment dictates microbial susceptibility to antimicrobial defense peptides

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Expression of beta-defensin 1 and 2 mRNA by human monocytes, macrophages and dendritic cells

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Antimicrobial activity of chicken and turkey heterophil peptides CHP1, CHP2, THP1, and THP3.

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Isolation of antimicrobial peptides from avian heterophils.

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Differential expression of alpha- and beta-defensins in human peripheral blood.

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An essential amino acid induces epithelial beta -defensin expression

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A chromosome 8 gene-cluster polymorphism with low human beta-defensin 2 gene copy number predisposes to Crohn disease of the colon

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Opsonic activity of MCP-1 and MCP-2, cationic peptides from rabbit alveolar macrophages

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Defensins: antimicrobial peptides of innate immunity

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Defensins. Natural peptide antibiotics of human neutrophils

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Human beta-defensin 4: a novel inducible peptide with a specific salt-sensitive spectrum of antimicrobial activity

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Penguin fathers preserve food for their chicks

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Recent progress in livestock genomics and potential impact on breeding programs

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Role of lipoteichoic acid in infection and inflammation

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Human beta-defensin-1 is a salt-sensitive antibiotic in lung that is inactivated in cystic fibrosis

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Alpha-defensin 1 (human neutrophil protein 1) as an antichemotactic agent for human polymorphonuclear leukocytes

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Trans-Golgi network sorting

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Peptide antibiotics

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Peptide antibiotics.

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Isolation and characterization of human beta -defensin-3, a novel human inducible peptide antibiotic

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Differential gene induction of human beta-defensins (hBD-1, -2, -3, and -4) in keratinocytes is inhibited by retinoic acid

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Psoriatic scales: a promising source for the isolation of human skin-derived antimicrobial proteins

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7 January 2021

Gallinacins: cysteine-rich antimicrobial peptides of chicken leukocytes

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Analyses of Five gallinacin genes and the Salmonella enterica serovar Enteritidis response in poultry

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7 January 2021

Foodborne bacterial infection and hospitalization: a registry-based study

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7 January 2021

The synthetic form of a novel chicken beta-defensin identified in silico is predominantly active against intestinal pathogens.

1 reference

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7 January 2021

Structural analysis of human beta-defensin-1 and its significance in urinary tract infection

1 reference

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Extensive normal copy number variation of a beta-defensin antimicrobial-gene cluster

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Enhancement of phagocytosis by corticostatin I (CSI) in cultured mouse peritoneal macrophages

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Single-nucleotide polymorphisms and haplotype analysis in beta-defensin genes in different ethnic populations

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Structure-activity relation of human beta-defensin 3: influence of disulfide bonds and cysteine substitution on antimicrobial activity and cytotoxicity

1 reference

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7 January 2021

Autolysis control hypotheses for tolerance to wall antibiotics

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Inducible expression of human beta-defensin 2 by Fusobacterium nucleatum in oral epithelial cells: multiple signaling pathways and role of commensal bacteria in innate immunity and the epithelial barrier

1 reference

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7 January 2021

Risk for infection with highly pathogenic influenza A virus (H5N1) in chickens, Hong Kong, 2002.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VETIMM.2007.12.006

7 January 2021

Epididymal Maturation and the Acrosome Reaction in Mouse Sperm: Response to Zona Pellucida Develops Coincident with Modification of M42 Antigen1

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Solution structure of spheniscin, a beta-defensin from the penguin stomach.

1 reference

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7 January 2021

Interaction of human defensins with Escherichia coli. Mechanism of bactericidal activity

1 reference

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7 January 2021

Defensins: antimicrobial and cytotoxic peptides of mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.VETIMM.2007.12.006

7 January 2021

Human defensin gene copy number polymorphisms: comprehensive analysis of independent variation in alpha- and beta-defensin regions at 8p22-p23.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VETIMM.2007.12.006

7 January 2021

Copy number polymorphisms are not a common feature of innate immune genes

1 reference

https://api.crossref.org/works/10.1016%2FJ.VETIMM.2007.12.006

7 January 2021

Bioinformatic discovery and initial characterisation of nine novel antimicrobial peptide genes in the chicken

1 reference

https://api.crossref.org/works/10.1016%2FJ.VETIMM.2007.12.006

7 January 2021

DNA vaccines encoding IL-2 linked to HPV-16 E7 antigen generate enhanced E7-specific CTL responses and antitumor activity

1 reference

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7 January 2021

Cationic defensins arise from charge-neutralized propeptides: a mechanism for avoiding leukocyte autocytotoxicity?

1 reference

https://api.crossref.org/works/10.1016%2FJ.VETIMM.2007.12.006

7 January 2021

The chicken host peptides, gallinacins 4, 7, and 9 have antimicrobial activity against Salmonella serovars.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VETIMM.2007.12.006

7 January 2021

The novel beta-defensin DEFB123 prevents lipopolysaccharide-mediated effects in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1016%2FJ.VETIMM.2007.12.006

7 January 2021

Defensins are mitogenic for epithelial cells and fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FJ.VETIMM.2007.12.006

7 January 2021

Epithelial cell-derived human beta-defensin-2 acts as a chemotaxin for mast cells through a pertussis toxin-sensitive and phospholipase C-dependent pathway

1 reference

https://api.crossref.org/works/10.1016%2FJ.VETIMM.2007.12.006

7 January 2021

Regulation of human beta-defensins by gastric epithelial cells in response to infection with Helicobacter pylori or stimulation with interleukin-1.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VETIMM.2007.12.006

7 January 2021

Systematic identification and integrative analysis of novel genes expressed specifically or predominantly in mouse epididymis

1 reference

https://api.crossref.org/works/10.1016%2FJ.VETIMM.2007.12.006

7 January 2021

Endogenous antimicrobial peptides and skin infections in atopic dermatitis

1 reference

https://api.crossref.org/works/10.1016%2FJ.VETIMM.2007.12.006

7 January 2021

In human epidermis, beta-defensin 2 is packaged in lamellar bodies

1 reference

https://api.crossref.org/works/10.1016%2FJ.VETIMM.2007.12.006

7 January 2021

Cross-species analysis of the mammalian beta-defensin gene family: presence of syntenic gene clusters and preferential expression in the male reproductive tract

1 reference

https://api.crossref.org/works/10.1016%2FJ.VETIMM.2007.12.006

7 January 2021

Human beta-defensins

1 reference

https://api.crossref.org/works/10.1016%2FJ.VETIMM.2007.12.006

7 January 2021

Microbial compounds induce the expression of pro-inflammatory cytokines, chemokines and human beta-defensin-2 in vaginal epithelial cells.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VETIMM.2007.12.006

7 January 2021

The multifaceted Paneth cell

1 reference

https://api.crossref.org/works/10.1016%2FJ.VETIMM.2007.12.006

7 January 2021

Distribution of new human beta-defensin genes clustered on chromosome 20 in functionally different segments of epididymis

1 reference

https://api.crossref.org/works/10.1016%2FJ.VETIMM.2007.12.006

7 January 2021

Salmonella carrier-state in hens: study of host resistance by a gene expression approach.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VETIMM.2007.12.006

7 January 2021

Salmonella carrier state in chicken: comparison of expression of immune response genes between susceptible and resistant animals.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VETIMM.2007.12.006

7 January 2021

Protection against enteric salmonellosis in transgenic mice expressing a human intestinal defensin

1 reference

https://api.crossref.org/works/10.1016%2FJ.VETIMM.2007.12.006

7 January 2021

Molecular cloning and characterization of three beta-defensins from canine testes

1 reference

https://api.crossref.org/works/10.1016%2FJ.VETIMM.2007.12.006

7 January 2021

Bioinformatic and expression analysis of novel porcine beta-defensins

1 reference

https://api.crossref.org/works/10.1016%2FJ.VETIMM.2007.12.006

7 January 2021

Interactions of mouse Paneth cell alpha-defensins and alpha-defensin precursors with membranes. Prosegment inhibition of peptide association with biomimetic membranes

1 reference

https://api.crossref.org/works/10.1016%2FJ.VETIMM.2007.12.006

7 January 2021

The solution structures of the human beta-defensins lead to a better understanding of the potent bactericidal activity of HBD3 against Staphylococcus aureus

1 reference

https://api.crossref.org/works/10.1016%2FJ.VETIMM.2007.12.006

7 January 2021

Human defensins

1 reference

https://api.crossref.org/works/10.1016%2FJ.VETIMM.2007.12.006

7 January 2021

Discovery of five conserved beta -defensin gene clusters using a computational search strategy

1 reference

https://api.crossref.org/works/10.1016%2FJ.VETIMM.2007.12.006

7 January 2021

Mammalian defensins in the antimicrobial immune response

1 reference

https://api.crossref.org/works/10.1016%2FJ.VETIMM.2007.12.006

7 January 2021

Duplication and selection in the evolution of primate beta-defensin genes

1 reference

https://api.crossref.org/works/10.1016%2FJ.VETIMM.2007.12.006

7 January 2021

Production of beta-defensins by human airway epithelia

1 reference

https://api.crossref.org/works/10.1016%2FJ.VETIMM.2007.12.006

7 January 2021

Wound healing and expression of antimicrobial peptides/polypeptides in human keratinocytes, a consequence of common growth factors

1 reference

https://api.crossref.org/works/10.1016%2FJ.VETIMM.2007.12.006

7 January 2021

Identification of three novel ostricacins: an update on the phylogenetic perspective of beta-defensins.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VETIMM.2007.12.006

7 January 2021

A cyclic antimicrobial peptide produced in primate leukocytes by the ligation of two truncated alpha-defensins

1 reference

https://api.crossref.org/works/10.1016%2FJ.VETIMM.2007.12.006

7 January 2021

Monocyte-chemotactic activity of defensins from human neutrophils

1 reference

https://api.crossref.org/works/10.1016%2FJ.VETIMM.2007.12.006

7 January 2021

Spheniscins, Avian β-Defensins in Preserved Stomach Contents of the King Penguin, Aptenodytes patagonicus

1 reference

https://api.crossref.org/works/10.1016%2FJ.VETIMM.2007.12.006

7 January 2021

The beta-defensin-fold family of polypeptides

1 reference

https://api.crossref.org/works/10.1016%2FJ.VETIMM.2007.12.006

7 January 2021

Intramolecular inhibition of human defensin HNP-1 by its propiece

1 reference

https://api.crossref.org/works/10.1016%2FJ.VETIMM.2007.12.006

7 January 2021

Human beta-defensin-1: an antimicrobial peptide of urogenital tissues

1 reference

https://api.crossref.org/works/10.1016%2FJ.VETIMM.2007.12.006

7 January 2021

Reversible deficiency of antimicrobial polypeptides in bacterial vaginosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.VETIMM.2007.12.006

7 January 2021

The beta-defensin gallinacin-6 is expressed in the chicken digestive tract and has antimicrobial activity against food-borne pathogens

1 reference

https://api.crossref.org/works/10.1016%2FJ.VETIMM.2007.12.006

7 January 2021

Differential regulation of porcine beta-defensins 1 and 2 upon Salmonella infection in the intestinal epithelial cell line IPI-2I.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VETIMM.2007.12.006

7 January 2021

Novel antimicrobial peptide of human epididymal duct origin

1 reference

https://api.crossref.org/works/10.1016%2FJ.VETIMM.2007.12.006

7 January 2021

Cutting edge: 1,25-dihydroxyvitamin D3 is a direct inducer of antimicrobial peptide gene expression

1 reference

https://api.crossref.org/works/10.1016%2FJ.VETIMM.2007.12.006

7 January 2021

Retrocyclin, an Antiretroviral θ-Defensin, Is a Lectin

1 reference

https://api.crossref.org/works/10.1016%2FJ.VETIMM.2007.12.006

7 January 2021

Infection of the reproductive tract and eggs with Salmonella enterica serovar pullorum in the chicken is associated with suppression of cellular immunity at sexual maturity

1 reference

https://api.crossref.org/works/10.1016%2FJ.VETIMM.2007.12.006

7 January 2021

A genetic variation map for chicken with 2.8 million single-nucleotide polymorphisms

1 reference

https://api.crossref.org/works/10.1016%2FJ.VETIMM.2007.12.006

7 January 2021

Engineering disulfide bridges to dissect antimicrobial and chemotactic activities of human beta-defensin 3

1 reference

https://api.crossref.org/works/10.1016%2FJ.VETIMM.2007.12.006

7 January 2021

Impact of pro segments on the folding and function of human neutrophil alpha-defensins

1 reference

https://api.crossref.org/works/10.1016%2FJ.VETIMM.2007.12.006

7 January 2021

A genome-wide screen identifies a single beta-defensin gene cluster in the chicken: implications for the origin and evolution of mammalian defensins

1 reference

https://api.crossref.org/works/10.1016%2FJ.VETIMM.2007.12.006

7 January 2021

Identification of multiple novel epididymis-specific beta-defensin isoforms in humans and mice

1 reference

https://api.crossref.org/works/10.1016%2FJ.VETIMM.2007.12.006

7 January 2021

Testis-specific expression of a novel mouse defensin-like gene, Tdl.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VETIMM.2007.12.006

7 January 2021

Beta-defensins: linking innate and adaptive immunity through dendritic and T cell CCR6

1 reference

https://api.crossref.org/works/10.1016%2FJ.VETIMM.2007.12.006

7 January 2021

Effects of age, egg-laying activity, and Salmonella-inoculation on the expressions of gallinacin mRNA in the vagina of the hen oviduct.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VETIMM.2007.12.006

7 January 2021

Cloning and expression of bovine neutrophil beta-defensins. Biosynthetic profile during neutrophilic maturation and localization of mature peptide to novel cytoplasmic dense granules.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VETIMM.2007.12.006

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VETIMM.2007.12.006

7 January 2021

ESP13.2, a member of the beta-defensin family, is a macaque sperm surface-coating protein involved in the capacitation process

1 reference

https://api.crossref.org/works/10.1016%2FJ.VETIMM.2007.12.006

7 January 2021

The carbohydrate structure of DEFB126, the major component of the cynomolgus Macaque sperm plasma membrane glycocalyx

1 reference

https://api.crossref.org/works/10.1016%2FJ.VETIMM.2007.12.006

7 January 2021

Antimicrobial peptides of multicellular organisms

1 reference

https://api.crossref.org/works/10.1016%2FJ.VETIMM.2007.12.006

7 January 2021

Gallinacin-3, an inducible epithelial beta-defensin in the chicken

1 reference

https://api.crossref.org/works/10.1016%2FJ.VETIMM.2007.12.006

7 January 2021

An epididymis-specific beta-defensin is important for the initiation of sperm maturation

1 reference

https://api.crossref.org/works/10.1016%2FJ.VETIMM.2007.12.006

7 January 2021

Mouse beta-defensin 3 is an inducible antimicrobial peptide expressed in the epithelia of multiple organs.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VETIMM.2007.12.006

7 January 2021

based on heuristic

inferred from DOI database lookup

Porcine epithelial beta-defensin 1 is expressed in the dorsal tongue at antimicrobial concentrations

1 reference

https://api.crossref.org/works/10.1016%2FJ.VETIMM.2007.12.006

7 January 2021

based on heuristic

inferred from DOI database lookup

Extracellular release of antimicrobial defensins by human polymorphonuclear leukocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18313763

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

From growth to autolysis: the murein hydrolases in Escherichia coli

1 reference

https://pubmed.ncbi.nlm.nih.gov/18313763

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Messenger RNA (mRNA) expression for the antimicrobial peptides beta-defensin-1 and beta-defensin-2 in the male rat reproductive tract: beta-defensin-1 mRNA in initial segment and caput epididymidis is regulated by androgens and not bacterial lipopol

1 reference

https://pubmed.ncbi.nlm.nih.gov/18313763

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mode of action of linear amphipathic alpha-helical antimicrobial peptides

1 reference

https://pubmed.ncbi.nlm.nih.gov/18313763

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human neutrophil defensins induce lung epithelial cell proliferation in vitro.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18313763

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Avian beta-defensin nomenclature: a community proposed update

1 reference

https://pubmed.ncbi.nlm.nih.gov/18313763

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

General outbreaks of infectious intestinal disease linked with poultry, England and Wales, 1992-1999.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18313763

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification, cloning and functional characterization of novel beta-defensins in the rat (Rattus norvegicus).

1 reference

https://pubmed.ncbi.nlm.nih.gov/18313763

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification, primary structures, and antibacterial activities of beta-defensins, a new family of antimicrobial peptides from bovine neutrophils.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18313763

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pathophysiological role of human beta-defensins 2 in gastric mucosa

1 reference

https://pubmed.ncbi.nlm.nih.gov/18313763

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human beta-defensin-1: A urinary peptide present in variant molecular forms and its putative functional implication

1 reference

https://pubmed.ncbi.nlm.nih.gov/18313763

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neutrophil defensins induce histamine secretion from mast cells: mechanisms of action

1 reference

https://pubmed.ncbi.nlm.nih.gov/18313763

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The pro region of human neutrophil defensin contains a motif that is essential for normal subcellular sorting.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18313763

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of litter in the transmission of Campylobacter jejuni.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18313763

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gene expression, immunolocalization, and secretion of human defensin-5 in human female reproductive tract

1 reference

https://pubmed.ncbi.nlm.nih.gov/18313763

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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