(Q28273189)

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Nigrostriatal dopaminergic neurodegeneration in the weaver mouse is mediated via neuroinflammation and alleviated by minocycline administration

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Europe PubMed Central

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21 December 2019

Nigrostriatal dopaminergic neurodegeneration in the weaver mouse is mediated via neuroinflammation and alleviated by minocycline administration (English)

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Europe PubMed Central

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21 December 2019

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neurodegeneration

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based on heuristic

inferred from title

Julie K Andersen

6

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21 December 2019

author name string

Jun Peng

1

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21 December 2019

Lin Xie

2

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21 December 2019

Fang Feng Stevenson

3

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21 December 2019

Simon Melov

4

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21 December 2019

Donato A Di Monte

5

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21 December 2019

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1 November 2006

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21 December 2019

Journal of Neuroscience

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21 December 2019

26

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21 December 2019

45

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21 December 2019

11644-11651

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21 December 2019

describes a project that uses

1 reference

Europe PubMed Central

22 June 2022

https://europepmc.org/article/PMC/6674792

based on heuristic

inferred from PubMed Central ID database lookup

The inflammatory reaction following 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine intoxication in mouse.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17093086

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A cell cycle alteration precedes apoptosis of granule cell precursors in the weaver mouse cerebellum

1 reference

https://pubmed.ncbi.nlm.nih.gov/17093086

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence of active nerve cell degeneration in the substantia nigra of humans years after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine exposure

1 reference

https://pubmed.ncbi.nlm.nih.gov/17093086

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of MHC class I heavy chain and beta2-microglobulin in rat brainstem motoneurons and nigral dopaminergic neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/17093086

12 December 2020

based on heuristic

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Mice deficient in cellular glutathione peroxidase show increased vulnerability to malonate, 3-nitropropionic acid, and 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine

1 reference

https://pubmed.ncbi.nlm.nih.gov/17093086

12 December 2020

based on heuristic

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Transgenic mice neuronally expressing baculoviral p35 are resistant to diverse types of induced apoptosis, including seizure-associated neurodegeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/17093086

12 December 2020

based on heuristic

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Minocycline inhibits microglial activation and protects nigral cells after 6-hydroxydopamine injection into mouse striatum

1 reference

https://pubmed.ncbi.nlm.nih.gov/17093086

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Minocycline prevents nigrostriatal dopaminergic neurodegeneration in the MPTP model of Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17093086

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase-9 activation results in downstream caspase-8 activation and bid cleavage in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17093086

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blockade of microglial activation is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17093086

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine induces apoptosis in mouse nigrostriatal glia. Relevance to nigral neuronal death and striatal neurochemical changes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17093086

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptotic molecules and MPTP-induced cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/17093086

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of caspases protects cerebellar granule cells of the weaver mouse from apoptosis and improves behavioral phenotype.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17093086

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuroinflammatory processes in Parkinson's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17093086

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective microglial activation in the rat rotenone model of Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17093086

12 December 2020

based on heuristic

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Novel anti-inflammatory therapy for Parkinson's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17093086

12 December 2020

based on heuristic

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A consideration of neural counting methods

1 reference

https://pubmed.ncbi.nlm.nih.gov/17093086

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Presence of reactive microglia in monkey substantia nigra years after 1‐methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine administration

1 reference

https://pubmed.ncbi.nlm.nih.gov/17093086

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The herbicide paraquat induces dopaminergic nigral apoptosis through sustained activation of the JNK pathway.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17093086

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuroprotection by tetracyclines

1 reference

https://pubmed.ncbi.nlm.nih.gov/17093086

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Superoxide dismutase/catalase mimetics are neuroprotective against selective paraquat-mediated dopaminergic neuron death in the substantial nigra: implications for Parkinson disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17093086

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reversal of Alzheimer's-like pathology and behavior in human APP transgenic mice by mutation of Asp664.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17093086

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Patterns of cell and fiber vulnerability in the mesostriatal system of the mutant mouse weaver. I. Gradients and compartments

1 reference

https://pubmed.ncbi.nlm.nih.gov/17093086

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular comparisons of the β2-microglobulin-binding site in class I major-histocompatibility-complex α-chains and proteins of related sequences

1 reference

https://pubmed.ncbi.nlm.nih.gov/17093086

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purkinje cell loss is due to a direct action of the weaver gene in Purkinje cells: evidence from chimeric mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17093086

12 December 2020

based on heuristic

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Development and death of external granular layer cells in the weaver mouse cerebellum: a quantitative study

1 reference

https://pubmed.ncbi.nlm.nih.gov/17093086

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anatomy and pathology of the basal ganglia

1 reference

https://pubmed.ncbi.nlm.nih.gov/17093086

12 December 2020

based on heuristic

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Mesencephalic dopamine cell deficit involves areas A8, A9 and A10 in weaver mutant mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17093086

12 December 2020

based on heuristic

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Reactive microglia are positive for HLA-DR in the substantia nigra of Parkinson's and Alzheimer's disease brains

1 reference

https://pubmed.ncbi.nlm.nih.gov/17093086

12 December 2020

based on heuristic

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Regional differences in cytoarchitecture of the weaver cerebellum suggest a new model for weaver gene action.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17093086

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of the weaver gene in dopamine-containing neural systems is dose-dependent and affects both striatal and nonstriatal regions.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17093086

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of Cortical Development: A View From Mutations in Mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17093086

12 December 2020

based on heuristic

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A qualitative and quantitative light microscopic study of the inferior olivary complex of normal, reeler, and weaver mutant mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17093086

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sequence of developmental abnormalities leading to granule cell deficit in cerebellar cortex of weaver mutant mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17093086

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abnormal rate of granule cell migration in the cerebellum of “weaver” mutant mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17093086

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Organization of cerebellar cortex secondary to deficit of granule cells in weaver mutant mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17093086

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Weaver mutation has differential effects on the dopamine-containing innervation of the limbic and nonlimbic striatum

1 reference

https://pubmed.ncbi.nlm.nih.gov/17093086

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dopamine deficiency in the weaver mutant mouse.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17093086

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A potassium channel mutation in weaver mice implicates membrane excitability in granule cell differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17093086

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brain beta 2-microglobulin levels are elevated in the striatum in Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17093086

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Detection of apoptosis in weaver cerebellum by electron microscopic in situ end-labeling of fragmented DNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/17093086

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of neuronal nitric oxide in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced dopaminergic neurotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/17093086

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell death in the midbrain of the murine mutation weaver.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17093086

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuropathology of Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17093086

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methods for determining numbers of cells and synapses: a case for more uniform standards of review

1 reference

https://pubmed.ncbi.nlm.nih.gov/17093086

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuron death in the substantia nigra of weaver mouse occurs late in development and is not apoptotic.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17093086

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Failed cell migration and death of purkinje cells and deep nuclear neurons in the weaver cerebellum.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17093086

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diverse cell death pathways result from a single missense mutation in weaver mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/17093086

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell death during development of testis and cerebellum in the mutant mouse weaver.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17093086

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis in neurological disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17093086

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transgenic mice expressing human Bcl-2 in their neurons are resistant to 6-hydroxydopamine and 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine neurotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/17093086

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of MHC class I--restricted antigen processing

1 reference

https://pubmed.ncbi.nlm.nih.gov/17093086

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Parkinson's disease. First of two parts

1 reference

https://pubmed.ncbi.nlm.nih.gov/17093086

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Girk2 expression in the ventral midbrain, cerebellum, and olfactory bulb and its relationship to the murine mutation weaver.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17093086

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.3447-06.2006

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17093086%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17093086%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17093086%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

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