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Endoplasmic reticulum stress and atherosclerosis
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scholarly article
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title
Endoplasmic reticulum stress and atherosclerosis
(English)
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main subject
endoplasmic reticulum
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atherosclerosis
1 reference
based on heuristic
inferred from title
author
Gökhan Hotamışlıgil
series ordinal
1
object named as
Gökhan S Hotamisligil
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language of work or name
English
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publication date
April 2010
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published in
Nature Medicine
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volume
16
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page(s)
396-9
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issue
4
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exact match
https://scigraph.springernature.com/pub.10.1038/nm0410-396
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cites work
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Signal integration in the endoplasmic reticulum unfolded protein response
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Treatment of diabetes and atherosclerosis by inhibiting fatty-acid-binding protein aP2
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20 March 2017
Inflammation and metabolic disorders
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Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance
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The luminal domain of ATF6 senses endoplasmic reticulum (ER) stress and causes translocation of ATF6 from the ER to the Golgi
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Lack of macrophage fatty-acid-binding protein aP2 protects mice deficient in apolipoprotein E against atherosclerosis
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20 March 2017
Atherosclerosis — An Inflammatory Disease
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20 March 2017
Regulation of hepatic lipogenesis by the transcription factor XBP1
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Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes
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20 March 2017
Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes
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CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity
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Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters
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7 April 2017
Reducing endoplasmic reticulum stress through a macrophage lipid chaperone alleviates atherosclerosis
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29 September 2017
Normalization of obesity-associated insulin resistance through immunotherapy
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Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice
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29 September 2017
Contributions of hyperhomocysteinemia to atherosclerosis: Causal relationship and potential mechanisms
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29 September 2017
Reduced apoptosis and plaque necrosis in advanced atherosclerotic lesions of Apoe-/- and Ldlr-/- mice lacking CHOP.
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29 September 2017
Macrophage deficiency of p38alpha MAPK promotes apoptosis and plaque necrosis in advanced atherosclerotic lesions in mice
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29 September 2017
Macrophage apoptosis in atherosclerosis: consequences on plaque progression and the role of endoplasmic reticulum stress
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29 September 2017
ER stress affects processing of MHC class I-associated peptides
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29 September 2017
Molecular and cellular mechanisms of the thrombotic complications of atherosclerosis
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29 September 2017
Valproate attenuates accelerated atherosclerosis in hyperglycemic apoE-deficient mice: evidence in support of a role for endoplasmic reticulum stress and glycogen synthase kinase-3 in lesion development and hepatic steatosis
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Nutrient sensing and inflammation in metabolic diseases
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29 September 2017
The multifaceted contributions of leukocyte subsets to atherosclerosis: lessons from mouse models
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29 September 2017
The endoplasmic reticulum stress response in immunity and autoimmunity
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29 September 2017
Dephosphorylation of translation initiation factor 2alpha enhances glucose tolerance and attenuates hepatosteatosis in mice
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Translating molecular discoveries into new therapies for atherosclerosis
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29 September 2017
Signal transducer and activator of transcription-1 is critical for apoptosis in macrophages subjected to endoplasmic reticulum stress in vitro and in advanced atherosclerotic lesions in vivo.
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Inhibition of apolipoprotein B100 secretion by lipid-induced hepatic endoplasmic reticulum stress in rodents
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Thematic review series: Adipocyte Biology. Adipocyte stress: the endoplasmic reticulum and metabolic disease
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Stimulation of an unfolded protein response impairs MHC class I expression
1 reference
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Myeloid lineage cell-restricted insulin resistance protects apolipoproteinE-deficient mice against atherosclerosis
1 reference
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The endoplasmic reticulum chaperone improves insulin resistance in type 2 diabetes.
1 reference
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29 September 2017
XBP1: a link between the unfolded protein response, lipid biosynthesis, and biogenesis of the endoplasmic reticulum.
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29 September 2017
Apoptosis of insulin-secreting cells induced by endoplasmic reticulum stress is amplified by overexpression of group VIA calcium-independent phospholipase A2 (iPLA2 beta) and suppressed by inhibition of iPLA2 beta
1 reference
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PubMed Central
reference URL
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29 September 2017
Chronic endoplasmic reticulum stress activates unfolded protein response in arterial endothelium in regions of susceptibility to atherosclerosis.
1 reference
stated in
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2 June 2018
UPR pathways combine to prevent hepatic steatosis caused by ER stress-mediated suppression of transcriptional master regulators.
1 reference
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2 June 2018
Free cholesterol overloading induced smooth muscle cells death and activated both ER- and mitochondrial-dependent death pathway.
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27 November 2018
Macrophage apoptosis exerts divergent effects on atherogenesis as a function of lesion stage.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2897068
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Endoplasmic reticulum stress, hepatocyte CD1d and NKT cell abnormalities in murine fatty livers.
1 reference
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PubMed Central
reference URL
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Macrophage insulin receptor deficiency increases ER stress-induced apoptosis and necrotic core formation in advanced atherosclerotic lesions.
1 reference
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PubMed Central
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27 November 2018
Activation of the unfolded protein response occurs at all stages of atherosclerotic lesion development in apolipoprotein E-deficient mice
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PubMed Central
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27 November 2018
Requirement of JNK2 for scavenger receptor A-mediated foam cell formation in atherogenesis
1 reference
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2897068
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27 November 2018
Involvement of endoplasmic reticulum stress in insulin resistance and diabetes
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2897068
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27 November 2018
The endoplasmic reticulum is the site of cholesterol-induced cytotoxicity in macrophages
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2897068
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27 November 2018
GM1-ganglioside-mediated activation of the unfolded protein response causes neuronal death in a neurodegenerative gangliosidosis
1 reference
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PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/20376052
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Monocytic origin of foam cells in human atherosclerotic plaques
1 reference
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PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/20376052
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Increased endoplasmic reticulum stress in atherosclerotic plaques associated with acute coronary syndrome
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/20376052
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1038/NM0410-396
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1160773
OpenCitations bibliographic resource ID
1160773
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1160773
PMCID
2897068
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1160773
PubMed ID
20376052
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1160773
ResearchGate publication ID
43073981
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