(Q28287317)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23500414%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

title

Angiopoietin signaling in the vasculature (English)

1 reference

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26 February 2020

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23500414%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

author name string

Lauri Eklund

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23500414%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

language of work or name

English

0 references

publication date

13 March 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23500414%20AND%20SRC:MED&resulttype=core&format=json

Experimental Cell Research

26 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23500414%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

volume

319

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23500414%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

issue

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23500414%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

page(s)

1271-1280

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23500414%20AND%20SRC:MED&resulttype=core&format=json

A novel endothelial cell surface receptor tyrosine kinase with extracellular epidermal growth factor homology domains

26 February 2020

cites work

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Targeting the ANG2/TIE2 axis inhibits tumor growth and metastasis by impairing angiogenesis and disabling rebounds of proangiogenic myeloid cells.

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Transcriptional and post‐translation regulation of the Tiel receptor by fluid shear stress changes in vascular endothelial cells

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Specific Induction of tie1 Promoter by Disturbed Flow in Atherosclerosis-Prone Vascular Niches and Flow-Obstructing Pathologies

7 January 2021

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Angiopoietins have distinct modular domains essential for receptor binding, dimerization and superclustering

7 January 2021

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7 January 2021

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Angiopoietins assemble distinct Tie2 signalling complexes in endothelial cell-cell and cell-matrix contacts

7 January 2021

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Angiopoietin-1 induces Kruppel-like factor 2 expression through a phosphoinositide 3-kinase/AKT-dependent activation of myocyte enhancer factor 2.

7 January 2021

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Angiopoietin-1/Tie2 signal augments basal Notch signal controlling vascular quiescence by inducing delta-like 4 expression through AKT-mediated activation of beta-catenin

7 January 2021

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Dominant-negative and targeted null mutations in the endothelial receptor tyrosine kinase, tek, reveal a critical role in vasculogenesis of the embryo

7 January 2021

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Angiopoietin-1 is essential in mouse vasculature during development and in response to injury

7 January 2021

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Loss of endothelial Tie1 receptor impairs lymphatic vessel development-brief report

7 January 2021

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Abnormal embryonic lymphatic vessel development in Tie1 hypomorphic mice

7 January 2021

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The receptor tyrosine kinase TIE is required for integrity and survival of vascular endothelial cells.

7 January 2021

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Defective remodeling and maturation of the lymphatic vasculature in Angiopoietin-2 deficient mice.

7 January 2021

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Effects of angiopoietin-2-blocking antibody on endothelial cell-cell junctions and lung metastasis

7 January 2021

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Ligand oligomerization state controls Tie2 receptor trafficking and angiopoietin-2-specific responses.

7 January 2021

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Stable interaction between alpha5beta1 integrin and Tie2 tyrosine kinase receptor regulates endothelial cell response to Ang-1.

7 January 2021

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Angiopoietin-2 differentially regulates angiogenesis through TIE2 and integrin signaling

7 January 2021

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Leakage-resistant blood vessels in mice transgenically overexpressing angiopoietin-1

7 January 2021

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Angiopoietin-1 protects the adult vasculature against plasma leakage.

7 January 2021

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Angiopoietin-1 is an antipermeability and anti-inflammatory agent in vitro and targets cell junctions

7 January 2021

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Angiopoietin-1 decreases plasma leakage by reducing number and size of endothelial gaps in venules.

7 January 2021

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Angiopoietin-1 prevents VEGF-induced endothelial permeability by sequestering Src through mDia.

7 January 2021

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Angiopoietin-1 requires p190 RhoGAP to protect against vascular leakage in vivo

7 January 2021

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Opposing effect of angiopoietin‐1 on VEGF‐mediated disruption of endothelial cell–cell interactions requires activation of PKCβ

7 January 2021

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Phosphorylation of endothelial nitric oxide synthase by atypical PKC zeta contributes to angiopoietin-1-dependent inhibition of VEGF-induced endothelial permeability in vitro.

7 January 2021

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Basal and angiopoietin-1-mediated endothelial permeability is regulated by sphingosine kinase-1

7 January 2021

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Angiopoietin-2 sensitizes endothelial cells to TNF-alpha and has a crucial role in the induction of inflammation

7 January 2021

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Hyperoxia causes angiopoietin 2-mediated acute lung injury and necrotic cell death

7 January 2021

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7 January 2021

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Control of vascular morphogenesis and homeostasis through the angiopoietin-Tie system

7 January 2021

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Angiopoietin-2 functions as an autocrine protective factor in stressed endothelial cells

7 January 2021

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FOXC2 controls Ang-2 expression and modulates angiogenesis, vascular patterning, remodeling, and functions in adipose tissue

7 January 2021

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Angiopoietin-1 negatively regulates expression and activity of tissue factor in endothelial cells

7 January 2021

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Angiopoietin-1 reduces VEGF-stimulated leukocyte adhesion to endothelial cells by reducing ICAM-1, VCAM-1, and E-selectin expression

7 January 2021

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Angiopoietin-1 variant, COMP-Ang1 attenuates hydrogen peroxide-induced acute lung injury

7 January 2021

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ABIN-2 protects endothelial cells from death and has a role in the antiapoptotic effect of angiopoietin-1

7 January 2021

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Tie1 attenuation reduces murine atherosclerosis in a dose-dependent and shear stress-specific manner

7 January 2021

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Receptor tyrosine kinase Tie-1 overexpression in endothelial cells upregulates adhesion molecules

7 January 2021

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Regulated proteolytic processing of Tie1 modulates ligand responsiveness of the receptor-tyrosine kinase Tie2.

7 January 2021

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VEGF induces Tie2 shedding via a phosphoinositide 3-kinase/Akt dependent pathway to modulate Tie2 signaling.

7 January 2021

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The molecular balance between receptor tyrosine kinases Tie1 and Tie2 is dynamically controlled by VEGF and TNFα and regulates angiopoietin signalling

7 January 2021

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Somatic mutations in angiopoietin receptor gene TEK cause solitary and multiple sporadic venous malformations

7 January 2021

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VEGF and angiopoietin signaling in tumor angiogenesis and metastasis

7 January 2021

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Contrasting actions of selective inhibitors of angiopoietin-1 and angiopoietin-2 on the normalization of tumor blood vessels

7 January 2021

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COMP-Ang1 potentiates the antitumor activity of 5-fluorouracil by improving tissue perfusion in murine Lewis lung carcinoma.

7 January 2021

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Angiopoietin-1 overexpression modulates vascular endothelium to facilitate tumor cell dissemination and metastasis establishment

7 January 2021

1 reference

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Angiopoietin 2 stimulates TIE2-expressing monocytes to suppress T cell activation and to promote regulatory T cell expansion.

7 January 2021

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VE-PTP controls blood vessel development by balancing Tie-2 activity

7 January 2021

1 reference

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Embryonic stem cell tumor model reveals role of vascular endothelial receptor tyrosine phosphatase in regulating Tie2 pathway in tumor angiogenesis

7 January 2021

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Randomized, double-blind, placebo-controlled phase II study of AMG 386 combined with weekly paclitaxel in patients with recurrent ovarian cancer

7 January 2021

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A human monoclonal anti-ANG2 antibody leads to broad antitumor activity in combination with VEGF inhibitors and chemotherapy agents in preclinical models

7 January 2021

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Double antiangiogenic protein, DAAP, targeting VEGF-A and angiopoietins in tumor angiogenesis, metastasis, and vascular leakage

7 January 2021

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Angiopoietin-2 may contribute to multiple organ dysfunction and death in sepsis*

7 January 2021

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Excess circulating angiopoietin-2 may contribute to pulmonary vascular leak in sepsis in humans

7 January 2021

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Effects of a synthetic PEG-ylated Tie-2 agonist peptide on endotoxemic lung injury and mortality

7 January 2021

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COMP-angiopoietin-1 decreases lipopolysaccharide-induced acute kidney injury

7 January 2021

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Biological action of angiopoietin-2 in a fibrin matrix model of angiogenesis is associated with activation of Tie2.

7 January 2021

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Angiopoietin 2 is a partial agonist/antagonist of Tie2 signaling in the endothelium

7 January 2021

1 reference

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Angiopoietin-2 causes pericyte dropout in the normal retina: evidence for involvement in diabetic retinopathy.

7 January 2021

1 reference

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High glucose increases angiopoietin-2 transcription in microvascular endothelial cells through methylglyoxal modification of mSin3A

7 January 2021

1 reference

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Renoprotective effect of COMP-angiopoietin-1 in db/db mice with type 2 diabetes

7 January 2021

1 reference

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Formation of a PKCζ/β-catenin complex in endothelial cells promotes angiopoietin-1-induced collective directional migration and angiogenic sprouting

7 January 2021

1 reference

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Angiopoietin-1 regulates endothelial cell survival through the phosphatidylinositol 3'-Kinase/Akt signal transduction pathway

7 January 2021

1 reference

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Angiopoietin-2 plasma dosage predicts time to first treatment and overall survival in chronic lymphocytic leukemia.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2013.03.011

Expression of angiopoietins and vascular endothelial growth factors and their clinical significance in acute myeloid leukemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2013.03.011

Synergistic effect of vascular endothelial growth factor and angiopoietin-2 on progression free survival in multiple myeloma.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2013.03.011

Angiopoietin-2 expression in breast cancer correlates with lymph node invasion and short survival.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2013.03.011

Angiopoietin-2 levels are associated with disease progression in metastatic malignant melanoma.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2013.03.011

Identification of serum angiopoietin-2 as a biomarker for clinical outcome of colorectal cancer patients treated with bevacizumab-containing therapy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2013.03.011

Angiopoietin-2 levels predict mortality in CKD patients

7 January 2021

1 reference

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The angiopoietin-Tie2 system as a therapeutic target in sepsis and acute lung injury

7 January 2021

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Plasma angiopoietin-2 in clinical acute lung injury: prognostic and pathogenetic significance

7 January 2021

1 reference

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Ratio of angiopoietin-2 to angiopoietin-1 as a predictor of mortality in acute lung injury patients.

7 January 2021

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Angiopoietin-2 in acute liver failure

7 January 2021

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Vascular endothelial hyperpermeability induces the clinical symptoms of Clarkson disease (the systemic capillary leak syndrome).

7 January 2021

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Using angiogenic factors and their soluble receptors to predict organ dysfunction in patients with disseminated intravascular coagulation associated with severe trauma

7 January 2021

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Angiogenic factors and their soluble receptors predict organ dysfunction and mortality in post-cardiac arrest syndrome

7 January 2021

1 reference

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Angiopoietin-2 in patients requiring renal replacement therapy in the ICU: relation to acute kidney injury, multiple organ dysfunction syndrome and outcome

7 January 2021

1 reference

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Angiopoietin-2, marker and mediator of endothelial activation with prognostic significance early after trauma?

7 January 2021

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The role of angiogenic factors in predicting clinical outcome in severe bacterial infection in Malawian children

7 January 2021

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10.1016/J.YEXCR.2013.03.011

7 January 2021

Identifiers

DOI

2 references

Consolidated OpenCitations Corpus – April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23500414%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

1 reference

Consolidated OpenCitations Corpus – April 2017

2 references

Consolidated OpenCitations Corpus – April 2017