(Q28293875)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20860463%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

title

Influence of host genetic factors on efavirenz plasma and intracellular pharmacokinetics in HIV-1-infected patients (English)

1 reference

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14 February 2020

0 references

1 reference

1 reference

1

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14 February 2020

Dominique Lison

series ordinal

4

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14 February 2020

2

Bernard Vandercam

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14 February 2020

3

Jean-Cyr Yombi

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14 February 2020

6

Vincent Haufroid

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14 February 2020

author name string

Pierre Wallemacq

series ordinal

5

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14 February 2020

language of work or name

English

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publication date

1 September 2010

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14 February 2020

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14 February 2020

volume

11

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14 February 2020

issue

9

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14 February 2020

page(s)

1223-1234

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Population pharmacokinetics and effects of efavirenz in patients with human immunodeficiency virus infection

14 February 2020

cites work

1 reference

Efavirenz plasma levels can predict treatment failure and central nervous system side effects in HIV-1-infected patients

21 January 2018

1 reference

Efavirenz plasma concentrations in HIV-infected patients: inter- and intraindividual variability and clinical effects

21 January 2018

1 reference

Impact of efavirenz on neuropsychological performance and symptoms in HIV-infected individuals

21 January 2018

1 reference

Influence of CYP2B6 polymorphism on plasma and intracellular concentrations and toxicity of efavirenz and nevirapine in HIV-infected patients

21 January 2018

1 reference

Glucuronidation of the antiretroviral drug efavirenz by UGT2B7 and an in vitro investigation of drug-drug interaction with zidovudine

21 January 2018

1 reference

Impact of CYP2B6 polymorphism on hepatic efavirenz metabolism in vitro.

21 January 2018

1 reference

CYP2B6, CYP2A6 and UGT2B7 genetic polymorphisms are predictors of efavirenz mid-dose concentration in HIV-infected patients

21 January 2018

1 reference

CYP2B6 (c.516G→T) and CYP2A6 (*9B and/or *17) polymorphisms are independent predictors of efavirenz plasma concentrations in HIV-infected patients

21 January 2018

1 reference

CYP2B6 variants and plasma efavirenz concentrations during antiretroviral therapy in Port-au-Prince, Haiti

21 January 2018

1 reference

The cytochrome P450 2B6 (CYP2B6) is the main catalyst of efavirenz primary and secondary metabolism: implication for HIV/AIDS therapy and utility of efavirenz as a substrate marker of CYP2B6 catalytic activity

21 January 2018

1 reference

Three haplotypes associated with CYP2A6 phenotypes in Caucasians

21 January 2018

1 reference

Single nucleotide polymorphism discovery and functional assessment of variation in the UDP-glucuronosyltransferase 2B7 gene

21 January 2018

1 reference

Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression

21 January 2018

1 reference

Clinical implications of CYP3A polymorphisms

21 January 2018

1 reference

Polymorphic CYP2B6: molecular mechanisms and emerging clinical significance

21 January 2018

1 reference

Associations between CYP2B6 polymorphisms and pharmacokinetics after a single dose of nevirapine or efavirenz in African americans

21 January 2018

1 reference

Multilocus genetic interactions and response to efavirenz-containing regimens: an adult AIDS clinical trials group study

21 January 2018

1 reference

Predictive value of known and novel alleles of CYP2B6 for efavirenz plasma concentrations in HIV-infected individuals.

21 January 2018

1 reference

Response to antiretroviral treatment in HIV-1-infected individuals with allelic variants of the multidrug resistance transporter 1: a pharmacogenetics study

21 January 2018

1 reference

MDR1 gene polymorphisms and phase 1 viral decay during HIV-1 infection: an adult AIDS Clinical Trials Group study

21 January 2018

1 reference

Pharmacogenetics of long-term responses to antiretroviral regimens containing Efavirenz and/or Nelfinavir: an Adult Aids Clinical Trials Group Study

21 January 2018

1 reference

Polymorphisms in human MDR1 (P-glycoprotein): recent advances and clinical relevance

21 January 2018

1 reference

An MDR1-3435 variant is associated with higher plasma nelfinavir levels and more rapid virologic response in HIV-1 infected children

21 January 2018

1 reference

Homozygous CYP2B6 *6 (Q172H and K262R) correlates with high plasma efavirenz concentrations in HIV-1 patients treated with standard efavirenz-containing regimens.

21 January 2018

1 reference

A novel polymorphism in ABCB1 gene, CYP2B6*6 and sex predict single-dose efavirenz population pharmacokinetics in Ugandans

21 January 2018

1 reference

Quantification of 8 HIV-protease inhibitors and 2 nonnucleoside reverse transcriptase inhibitors by ultra-performance liquid chromatography with diode array detection.

21 January 2018

1 reference

Validation and clinical application of a high performance liquid chromatography tandem mass spectrometry (LC-MS/MS) method for the quantitative determination of 10 anti-retrovirals in human peripheral blood mononuclear cells.

21 January 2018

1 reference

Phosphorylation of 3'-azido-3'-deoxythymidine and selective interaction of the 5'-triphosphate with human immunodeficiency virus reverse transcriptase

21 January 2018

1 reference

Influence of the cytochrome P450 2B6 genotype on population pharmacokinetics of efavirenz in human immunodeficiency virus patients

21 January 2018

1 reference

Cytochrome p450 gene expression levels in peripheral blood mononuclear cells in comparison with the liver.

21 January 2018

1 reference

Genetic susceptibility of lung cancer associated with common variants in the 3' untranslated regions of the adenosine triphosphate-binding cassette B1 (ABCB1) and ABCC1 candidate transporter genes for carcinogen export

21 January 2018

1 reference

Functional significance of UDP-glucuronosyltransferase variants in the metabolism of active tamoxifen metabolites

21 January 2018

1 reference

Implications of T-cell P-glycoprotein activity during HIV-1 infection and its therapy

21 January 2018

1 reference

A "silent" polymorphism in the MDR1 gene changes substrate specificity

21 January 2018

1 reference

Efavirenz intoxication due to slow hepatic metabolism

21 January 2018

1 reference

Influence of 516G>T polymorphisms at the gene encoding the CYP450-2B6 isoenzyme on efavirenz plasma concentrations in HIV-infected subjects

21 January 2018

1 reference

Successful efavirenz dose reduction in HIV type 1-infected individuals with cytochrome P450 2B6 *6 and *26.

21 January 2018

1 reference

ABC transporters, cytochromes P450 and their main transcription factors: expression at the human blood-brain barrier.

21 January 2018

1 reference

Influence of polymorphisms within the CX3CR1 and MDR-1 genes on initial antiretroviral therapy response

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.2217/PGS.10.94

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20860463%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

1 reference