(Q28304255)

2

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Hideki Yamamoto

3

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Takayuki Hanamoto

4

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Hironobu Kikuchi

5

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Kazushige Furuya

6

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Masahiro Asaka

7

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Domenico Delia

8

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Akira Nakagawara

Journal of Biological Chemistry

9

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language of work or name

English

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publication date

3 August 2007

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published in

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volume

282

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page(s)

22993-3004

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issue

31

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cites work

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Evidence for a transcriptional activation function of BRCA1 C-terminal region

21 January 2018

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BRCA1 is a component of the RNA polymerase II holoenzyme

21 January 2018

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21 January 2018

Protein sequence motifs

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Two cellular proteins that bind to wild-type but not mutant p53

21 January 2018

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The second BRCT domain of BRCA1 proteins interacts with p53 and stimulates transcription from the p21WAF1/CIP1 promoter

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M611412200

Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1

21 January 2018

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NFBD1/KIAA0170 is a novel nuclear transcriptional transactivator with BRCT domain

21 January 2018

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MDC1 is required for the intra-S-phase DNA damage checkpoint

21 January 2018

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MDC1 is coupled to activated CHK2 in mammalian DNA damage response pathways

21 January 2018

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MDC1 is a mediator of the mammalian DNA damage checkpoint

21 January 2018

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NFBD1/MDC1 regulates ionizing radiation-induced focus formation by DNA checkpoint signaling and repair factors

21 January 2018

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NFBD1, like 53BP1, is an early and redundant transducer mediating Chk2 phosphorylation in response to DNA damage

21 January 2018

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NFBD1/KIAA0170 is a chromatin-associated protein involved in DNA damage signaling pathways

21 January 2018

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MDC1 regulates DNA-PK autophosphorylation in response to DNA damage

21 January 2018

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Enhanced phosphorylation of p53 by ATM in response to DNA damage

21 January 2018

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Activation of the ATM kinase by ionizing radiation and phosphorylation of p53

21 January 2018

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DNA damage-induced activation of p53 by the checkpoint kinase Chk2

21 January 2018

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Phosphorylation site interdependence of human p53 post-translational modifications in response to stress

21 January 2018

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MDC1/NFBD1: a key regulator of the DNA damage response in higher eukaryotes

21 January 2018

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MDC1 maintains genomic stability by participating in the amplification of ATM-dependent DNA damage signals

21 January 2018

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DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2

21 January 2018

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Serine15 phosphorylation stimulates p53 transactivation but does not directly influence interaction with HDM2.

21 January 2018

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NFBD1/Mdc1 mediates ATR-dependent DNA damage response

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Functions of the MDM2 oncoprotein

21 January 2018

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ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways

21 January 2018

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The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M611412200

Nucleolar Arf sequesters Mdm2 and activates p53

21 January 2018

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Association of p19(ARF) with Mdm2 inhibits ubiquitin ligase activity of Mdm2 for tumor suppressor p53.

21 January 2018

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ATM-dependent phosphorylation of Mdm2 on serine 395: role in p53 activation by DNA damage

21 January 2018

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BRCT Repeats As Phosphopeptide-Binding Modules Involved in Protein Targeting

21 January 2018

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Phosphopeptide Binding Specificities of BRCA1 COOH-terminal (BRCT) Domains

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M611412200

The BRCT Domain Is a Phospho-Protein Binding Domain

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M611412200

An essential role for NF-kappaB in preventing TNF-alpha-induced cell death

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M611412200

Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappaB activation prevents cell death

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M611412200

Suppression of TNF-alpha-induced apoptosis by NF-kappaB

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M611412200

TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB

21 January 2018

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NF-kappaB activation by camptothecin. A linkage between nuclear DNA damage and cytoplasmic signaling events

21 January 2018

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NF-kappa B activation mediates doxorubicin-induced cell death in N-type neuroblastoma cells

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M611412200

ATM is required for IkappaB kinase (IKKk) activation in response to DNA double strand breaks

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611412200

ATM and the catalytic subunit of DNA-dependent protein kinase activate NF-kappaB through a common MEK/extracellular signal-regulated kinase/p90(rsk) signaling pathway in response to distinct forms of DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611412200

p53 stabilization is decreased upon NFkappaB activation: a role for NFkappaB in acquisition of resistance to chemotherapy

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M611412200

STAT-1 facilitates the ATM activated checkpoint pathway following DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611412200

Transcriptional activation by BRCA1

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M611412200