(Q28304623)

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Polymorphisms of the toll-like receptor 2 and 4 genes are associated with faster progression and a more severe course of sepsis in critically ill patients

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Polymorphisms of the toll-like receptor 2 and 4 genes are associated with faster progression and a more severe course of sepsis in critically ill patients (English)

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toll-like receptor

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8

object named as

Claudia Spies

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Irit Nachtigall

1

object named as

Irit Nachtigall

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Klaus-Dieter Wernecke

7

object named as

Klaus D Wernecke

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author name string

Andrey Tamarkin

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Sascha Tafelski

3

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Andreas Weimann

4

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Andreas Rothbart

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Susanne Heim

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language of work or name

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publication date

February 2014

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Journal of International Medical Research

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42

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1

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93-110

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Relevance of mutations in the TLR4 receptor in patients with gram-negative septic shock

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https://api.crossref.org/works/10.1177/0300060513504358

21 April 2017

Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008

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https://api.crossref.org/works/10.1177/0300060513504358

21 April 2017

TLR4 mutations are associated with endotoxin hyporesponsiveness in humans

1 reference

https://api.crossref.org/works/10.1177/0300060513504358

21 April 2017

The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors

1 reference

https://api.crossref.org/works/10.1177/0300060513504358

21 April 2017

Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components

1 reference

https://api.crossref.org/works/10.1177/0300060513504358

21 April 2017

Phosphoinositide-mediated adaptor recruitment controls Toll-like receptor signaling

1 reference

https://api.crossref.org/works/10.1177%2F0300060513504358

21 January 2018

Toll-like receptor-2 mediates lipopolysaccharide-induced cellular signalling

1 reference

https://api.crossref.org/works/10.1177%2F0300060513504358

21 January 2018

The PIRO concept: P is for predisposition

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https://api.crossref.org/works/10.1177%2F0300060513504358

21 January 2018

Single nucleotide polymorphisms of Toll-like receptors and susceptibility to infectious disease

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https://api.crossref.org/works/10.1177%2F0300060513504358

21 January 2018

Differential involvement of toll-like receptors 2 and 4 in the host response to acute respiratory infections with wild-type and mutant Haemophilus influenzae strains

1 reference

https://api.crossref.org/works/10.1177%2F0300060513504358

21 January 2018

APACHE II: a severity of disease classification system

1 reference

https://api.crossref.org/works/10.1177%2F0300060513504358

21 January 2018

Use of the SOFA score to assess the incidence of organ dysfunction/failure in intensive care units: results of a multicenter, prospective study. Working group on "sepsis-related problems" of the European Society of Intensive Care Medicine.

1 reference

https://api.crossref.org/works/10.1177%2F0300060513504358

21 January 2018

High frequency of polymorphism Arg753Gln of the Toll-like receptor-2 gene detected by a novel allele-specific PCR

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https://api.crossref.org/works/10.1177%2F0300060513504358

21 January 2018

Influence of genetic variations in TLR4 and TIRAP/Mal on the course of sepsis and pneumonia and cytokine release: an observational study in three cohorts

1 reference

https://api.crossref.org/works/10.1177%2F0300060513504358

21 January 2018

The presence of functionally relevant toll-like receptor polymorphisms does not significantly correlate with development or outcome of sepsis

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https://api.crossref.org/works/10.1177%2F0300060513504358

21 January 2018

Toll-like receptor 4 plays a crucial role in the immune-adrenal response to systemic inflammatory response syndrome

1 reference

https://api.crossref.org/works/10.1177%2F0300060513504358

21 January 2018

Toll-like receptor pathway signaling is differently regulated in neutrophils and peripheral mononuclear cells of patients with sepsis, severe sepsis, and septic shock.

1 reference

https://api.crossref.org/works/10.1177%2F0300060513504358

21 January 2018

Hemorrhage-induced acute lung injury is TLR-4 dependent.

1 reference

https://api.crossref.org/works/10.1177%2F0300060513504358

21 January 2018

Reduced myocardial ischemia-reperfusion injury in toll-like receptor 4-deficient mice

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https://api.crossref.org/works/10.1177%2F0300060513504358

21 January 2018

TLR4 activation mediates kidney ischemia/reperfusion injury

1 reference

https://api.crossref.org/works/10.1177%2F0300060513504358

21 January 2018

Activation of airway epithelial cells by toll-like receptor agonists

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https://api.crossref.org/works/10.1177%2F0300060513504358

21 January 2018

Multiple TLRs activate EGFR via a signaling cascade to produce innate immune responses in airway epithelium

1 reference

https://api.crossref.org/works/10.1177%2F0300060513504358

21 January 2018

Heterozygous toll-like receptor 2 polymorphism does not affect lipoteichoic acid-induced chemokine and inflammatory responses

1 reference

https://api.crossref.org/works/10.1177%2F0300060513504358

21 January 2018

Cutting edge: TLR2-deficient and MyD88-deficient mice are highly susceptible to Staphylococcus aureus infection

1 reference

https://api.crossref.org/works/10.1177%2F0300060513504358

21 January 2018

A TLR2 polymorphism is associated with type 1 diabetes and allergic asthma.

1 reference

https://api.crossref.org/works/10.1177%2F0300060513504358

21 January 2018

Demonstration of increased toll-like receptor 2 and toll-like receptor 4 expression in monocytes of type 1 diabetes mellitus patients with microvascular complications

1 reference

https://api.crossref.org/works/10.1177%2F0300060513504358

21 January 2018

TLR2 expression and signaling-dependent inflammation impair wound healing in diabetic mice

1 reference

https://api.crossref.org/works/10.1177%2F0300060513504358

21 January 2018

Monocyte mRNA phenotype and adverse outcomes from pediatric multiple organ dysfunction syndrome

1 reference

https://api.crossref.org/works/10.1177%2F0300060513504358

21 January 2018

Toll-like receptor 4 modulation as a strategy to treat sepsis

1 reference

https://api.crossref.org/works/10.1177%2F0300060513504358

21 January 2018

Toll-like Receptor 4 Polymorphisms and Atherogenesis

1 reference

https://api.crossref.org/works/10.1177%2F0300060513504358

21 January 2018

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