(Q34026949)

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Influence of genetic variations in TLR4 and TIRAP/Mal on the course of sepsis and pneumonia and cytokine release: an observational study in three cohorts

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scholarly article

1 reference

Europe PubMed Central

30 July 2017

Influence of genetic variations in TLR4 and TIRAP/Mal on the course of sepsis and pneumonia and cytokine release: an observational study in three cohorts (English)

1 reference

Europe PubMed Central

30 July 2017

0 references

toll-like receptor

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object named as

Oliver Kumpf

1

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Evangelos J Giamarellos-Bourboulis

object named as

Evangelos J Giamarellos-Bourboulis

2

0 references

16

object named as

Mihai G Netea

1 reference

Europe PubMed Central

30 July 2017

10

object named as

Bart Ferwerda

1 reference

Europe PubMed Central

30 July 2017

Maria Mouktaroudi

5

object named as

Maria Mouktaroudi

1 reference

Europe PubMed Central

30 July 2017

6

object named as

Djin-Ye Oh

1 reference

Europe PubMed Central

30 July 2017

Jos W. M. van der Meer,

14

object named as

Jos W M van der Meer

1 reference

Europe PubMed Central

30 July 2017

author name string

Alexander Koch

3

1 reference

Europe PubMed Central

30 July 2017

Lutz Hamann

4

1 reference

Europe PubMed Central

30 July 2017

Eicke Latz

7

1 reference

Europe PubMed Central

30 July 2017

Eva Lorenz

8

1 reference

Europe PubMed Central

30 July 2017

David A Schwartz

9

1 reference

Europe PubMed Central

30 July 2017

Christina Routsi

11

1 reference

Europe PubMed Central

30 July 2017

Chryssanthi Skalioti

12

1 reference

Europe PubMed Central

30 July 2017

Bart-Jan Kullberg

13

1 reference

Europe PubMed Central

30 July 2017

Peter M Schlag

15

1 reference

Europe PubMed Central

30 July 2017

Kai Zacharowski

17

1 reference

Europe PubMed Central

30 July 2017

Ralf R Schumann

18

1 reference

Europe PubMed Central

30 July 2017

publication date

3 June 2010

1 reference

Europe PubMed Central

30 July 2017

1 reference

Europe PubMed Central

30 July 2017

14

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Europe PubMed Central

30 July 2017

3

1 reference

Europe PubMed Central

30 July 2017

R103

1 reference

Europe PubMed Central

30 July 2017

https://scigraph.springernature.com/pub.10.1186/cc9047

0 references

Low frequency of the TIRAP S180L polymorphism in Africa, and its potential role in malaria, sepsis, and leprosy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911747

5 July 2018

Functional and genetic evidence that the Mal/TIRAP allele variant 180L has been selected by providing protection against septic shock

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911747

5 July 2018

Inflammatory response and cardioprotection during open-heart surgery: the importance of anaesthetics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911747

5 July 2018

Recognition of microorganisms and activation of the immune response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911747

5 July 2018

TLR4 polymorphisms, infectious diseases, and evolutionary pressure during migration of modern humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911747

5 July 2018

Role for MyD88-independent, TRIF pathway in lipid A/TLR4-induced endotoxin tolerance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911747

5 July 2018

The vaccine adjuvant monophosphoryl lipid A as a TRIF-biased agonist of TLR4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911747

5 July 2018

Stress molecules in sepsis and systemic inflammatory response syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911747

5 July 2018

A Mal functional variant is associated with protection against invasive pneumococcal disease, bacteremia, malaria and tuberculosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911747

5 July 2018

A polymorphism in Toll-interleukin 1 receptor domain containing adaptor protein is associated with susceptibility to meningeal tuberculosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911747

5 July 2018

Phosphoinositide-mediated adaptor recruitment controls Toll-like receptor signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911747

5 July 2018

Early apoptosis of blood monocytes in the septic host: is it a mechanism of protection in the event of septic shock?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911747

5 July 2018

Toll-like receptor 4 plays a crucial role in the immune-adrenal response to systemic inflammatory response syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911747

5 July 2018

Pathogen recognition and innate immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911747

5 July 2018

Genetic polymorphisms and sepsis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911747

5 July 2018

Single nucleotide polymorphisms of Toll-like receptors and susceptibility to infectious disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911747

5 July 2018

Inhibition of lipopolysaccharide-induced interferon regulatory factor 3 activation and protection from septic shock by hydroxystilbenes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911747

5 July 2018

TLRs: differential adapter utilization by toll-like receptors mediates TLR-specific patterns of gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911747

5 July 2018

Rapid and inexpensive real-time PCR for genotyping functional polymorphisms within the Toll-like receptor -2, -4, and -9 genes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911747

5 July 2018

Genomic polymorphisms in sepsis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911747

5 July 2018

Innate immunity: an overview

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911747

5 July 2018

Genetic polymorphisms in sepsis and septic shock: role in prognosis and potential for therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911747

5 July 2018

Proinflammatory cytokines and sepsis syndrome: not enough, or too much of a good thing?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911747

5 July 2018

Assay of locus-specific genetic load implicates rare Toll-like receptor 4 mutations in meningococcal susceptibility

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911747

5 July 2018

2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911747

5 July 2018

Relevance of mutations in the TLR4 receptor in patients with gram-negative septic shock

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911747

5 July 2018

Ventilator-associated pneumonia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911747

5 July 2018

Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911747

5 July 2018

Proinflammatory cytokines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911747

5 July 2018

Pathogenetic mechanisms of septic shock

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911747

5 July 2018

Immunosuppression associated with interleukin-1R-associated-kinase-M upregulation predicts mortality in Gram-negative sepsis (melioidosis).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911747

29 October 2018

Response to systemic endotoxemia among humans bearing polymorphisms of the Toll-like receptor 4 (hTLR4).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911747

29 October 2018

Pre- and postoperative cytokine release after in vitro whole blood lipopolysaccharide stimulation and frequent toll-like receptor 4 polymorphisms.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911747

29 October 2018

TNF-alpha promoter, Nod2 and toll-like receptor-4 polymorphisms and the in vivo and ex vivo response to endotoxin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911747

29 October 2018

Inflammatory response after open heart surgery: release of heat-shock protein 70 and signaling through toll-like receptor-4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911747

29 October 2018

Determination of the TLR4 genotype using allele-specific PCR

1 reference

https://pubmed.ncbi.nlm.nih.gov/20525286

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A functional polymorphism of toll-like receptor 4 is not associated with likelihood or severity of meningococcal disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/20525286

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human toll-like receptor 4 mutations but not CD14 polymorphisms are associated with an increased risk of gram-negative infections

1 reference

https://pubmed.ncbi.nlm.nih.gov/20525286

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Risk factors for postoperative infectious complications in noncolorectal abdominal surgery: a multivariate analysis based on a prospective multicenter study of 4718 patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/20525286

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic and environmental influences on premature death in adult adoptees

1 reference

https://pubmed.ncbi.nlm.nih.gov/20525286

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/20525286

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional consequences of the Asp299Gly Toll-like receptor-4 polymorphism

1 reference

https://pubmed.ncbi.nlm.nih.gov/20525286

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Does soluble triggering receptor expressed on myeloid cells-1 play any role in the pathogenesis of septic shock?

1 reference

https://pubmed.ncbi.nlm.nih.gov/20525286

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Soluble triggering receptor expressed on myeloid cells 1 as an anti-inflammatory mediator in sepsis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20525286

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pathophysiology of sepsis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20525286

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TLR SIGNALING PATHWAY IN PATIENTS WITH SEPSIS

1 reference

https://pubmed.ncbi.nlm.nih.gov/20525286

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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1 reference

Europe PubMed Central

30 July 2017

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1 reference

Europe PubMed Central

30 July 2017

1 reference

Europe PubMed Central

30 July 2017

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