(Q28307097)

English

Interaction of MAD2 with the carboxyl terminus of the insulin receptor but not with the IGFIR. Evidence for release from the insulin receptor after activation

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scholarly article

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Interaction of MAD2 with the carboxyl terminus of the insulin receptor but not with the IGFIR. Evidence for release from the insulin receptor after activation (English)

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1 reference

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3

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T A Gustafson

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author name string

T J O'Neill

1

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Y Zhu

2

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language of work or name

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publication date

11 April 1997

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Journal of Biological Chemistry

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272

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15

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10035-40

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Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein

1 reference

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Mutation of the insulin receptor at tyrosine 960 inhibits signal transmission but does not affect its tyrosine kinase activity

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Characterization of an interaction between insulin receptor substrate 1 and the insulin receptor by using the two-hybrid system

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Phosphotyrosine-dependent interaction of SHC and insulin receptor substrate 1 with the NPEY motif of the insulin receptor via a novel non-SH2 domain

1 reference

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Structure of the IRS-1 PTB domain bound to the juxtamembrane region of the insulin receptor

1 reference

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Pleiotropic insulin signals are engaged by multisite phosphorylation of IRS-1

1 reference

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A novel transforming protein (SHC) with an SH2 domain is implicated in mitogenic signal transduction

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Distinct modes of interaction of SHC and insulin receptor substrate-1 with the insulin receptor NPEY region via non-SH2 domains

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Involvement of Shc in insulin- and epidermal growth factor-induced activation of p21ras

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Role of IRS-2 in insulin and cytokine signalling

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IRS-1: essential for insulin- and IL-4-stimulated mitogenesis in hematopoietic cells

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The inability of phosphatidylinositol 3-kinase activation to stimulate GLUT4 translocation indicates additional signaling pathways are required for insulin-stimulated glucose uptake

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Non-SH2 domains within insulin receptor substrate-1 and SHC mediate their phosphotyrosine-dependent interaction with the NPEY motif of the insulin-like growth factor I receptor

1 reference

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Interaction of insulin receptor substrate-2 (IRS-2) with the insulin and insulin-like growth factor I receptors. Evidence for two distinct phosphotyrosine-dependent interaction domains within IRS-2

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Interaction of a GRB-IR splice variant (a human GRB10 homolog) with the insulin and insulin-like growth factor I receptors. Evidence for a role in mitogenic signaling

1 reference

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Cdi1, a human G1 and S phase protein phosphatase that associates with Cdk2

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Fused protein domains inhibit DNA binding by LexA

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Mxi1, a protein that specifically interacts with Max to bind Myc-Max recognition sites

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High efficiency transformation of intact yeast cells using single stranded nucleic acids as a carrier

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Rapid and efficient site-specific mutagenesis without phenotypic selection

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Cell cycle control of the yeast HO gene: cis- and trans-acting regulators

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Identification of a human mitotic checkpoint gene: hsMAD2

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Expression of a functional human insulin receptor from a cloned cDNA in Chinese hamster ovary cells

1 reference

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The mitotic feedback control gene MAD2 encodes the alpha-subunit of a prenyltransferase

1 reference

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Interaction between the Grb10 SH2 domain and the insulin receptor carboxyl terminus

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Grb-IR: a SH2-domain-containing protein that binds to the insulin receptor and inhibits its function

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Association of spindle assembly checkpoint component XMAD2 with unattached kinetochores

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S. cerevisiae genes required for cell cycle arrest in response to loss of microtubule function

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A MAP kinase-dependent spindle assembly checkpoint in Xenopus egg extracts

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Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes

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Identifiers

10.1074/JBC.272.15.10035

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