(Q28344277)

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Phosphorylation states of Cdc42 and RhoA regulate their interactions with Rho GDP dissociation inhibitor and their extraction from biological membranes

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scholarly article

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Phosphorylation states of Cdc42 and RhoA regulate their interactions with Rho GDP dissociation inhibitor and their extraction from biological membranes (English)

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phosphorylation

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based on heuristic

inferred from title

author name string

Marie-Annick Forget

1

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Richard R Desrosiers

2

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Denis Gingras

3

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Richard Béliveau

4

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language of work or name

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publication date

15 January 2002

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Biochemical Journal

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361

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Pt 2

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243-54

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Differential localization of Rho GTPases in live cells: regulation by hypervariable regions and RhoGDI binding

1 reference

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Cyclic GMP-dependent protein kinase signaling pathway inhibits RhoA-induced Ca2+ sensitization of contraction in vascular smooth muscle

1 reference

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An open conformation of switch I revealed by the crystal structure of a Mg2+-free form of RHOA complexed with GDP. Implications for the GDP/GTP exchange mechanism

1 reference

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How RhoGDI binds Rho

1 reference

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The interaction between rac1 and its guanine nucleotide dissociation inhibitor (GDI), monitored by a single fluorescent coumarin attached to GDI

1 reference

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Rho GTPases and the actin cytoskeleton

1 reference

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Crystal structure of RhoA-GDP and its functional implications

1 reference

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Direct interaction of the Rho GDP dissociation inhibitor with ezrin/radixin/moesin initiates the activation of the Rho small G protein

1 reference

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C-terminal binding domain of Rho GDP-dissociation inhibitor directs N-terminal inhibitory peptide to GTPases

1 reference

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

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Phosphorylation of two small GTP-binding proteins of the Rab family by p34cdc2

1 reference

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Improved method for high efficiency transformation of intact yeast cells

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Reversible phosphorylation--dephosphorylation determines the localization of rab4 during the cell cycle

1 reference

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Characterization of a Rac1- and RhoGDI-associated lipid kinase signaling complex

1 reference

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20 March 2017

Rho GTPases and signaling networks

1 reference

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20 March 2017

cGMP-dependent protein kinase phosphorylates and inactivates RhoA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222304

29 September 2017

Regulation of cell function by Rho family GTPases

1 reference

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29 September 2017

Akt protein kinase inhibits Rac1-GTP binding through phosphorylation at serine 71 of Rac1.

1 reference

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29 September 2017

Rho guanine dissociation inhibitors: pivotal molecules in cellular signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222304

29 September 2017

Rnd proteins: a new family of Rho-related proteins that interfere with the assembly of filamentous actin structures and cell adhesion

1 reference

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29 September 2017

cAMP-induced morphological changes are counteracted by the activated RhoA small GTPase and the Rho kinase ROKalpha

1 reference

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Elevation of intracellular cAMP inhibits RhoA activation and integrin-dependent leukocyte adhesion induced by chemoattractants.

1 reference

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Protein kinase A phosphorylation of RhoA mediates the morphological and functional effects of cyclic AMP in cytotoxic lymphocytes

1 reference

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Rho as a regulator of the cytoskeleton.

1 reference

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A ras-related protein is phosphorylated and translocated by agonists that increase cAMP levels in human platelets

1 reference

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Molecular cloning and characterization of a novel type of regulatory protein (GDI) for the rho proteins, ras p21-like small GTP-binding proteins.

1 reference

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Methylation and proteolysis are essential for efficient membrane binding of prenylated p21K-ras(B).

1 reference

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29 September 2017

A CAAX or a CAAL motif and a second signal are sufficient for plasma membrane targeting of ras proteins.

1 reference

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29 September 2017

Small GTP-binding proteins

1 reference

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29 September 2017

RhoA prenylation is required for promotion of cell growth and transformation and cytoskeleton organization but not for induction of serum response element transcription.

1 reference

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Multiple probing of an immunoblot membrane using a non-block technique: advantages in speed and sensitivity

1 reference

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2 June 2018

Biologically active lipids are regulators of Rac.GDI complexation

1 reference

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Consequences of weak interaction of rho GDI with the GTP-bound forms of rho p21 and rac p21.

1 reference

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2 June 2018

Purification of recombinant Rho/Rac/G25K from Escherichia coli.

1 reference

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2 June 2018

A polybasic domain or palmitoylation is required in addition to the CAAX motif to localize p21ras to the plasma membrane

1 reference

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2 June 2018

Purification and characterization from bovine brain cytosol of a novel regulatory protein inhibiting the dissociation of GDP from and the subsequent binding of GTP to rhoB p20, a ras p21-like GTP-binding protein.

1 reference

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2 June 2018

Post-translational modifications of the C-terminal region of the rho protein are important for its interaction with membranes and the stimulatory and inhibitory GDP/GTP exchange proteins.

1 reference

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2 June 2018

Enhancement of the actions of smg p21 GDP/GTP exchange protein by the protein kinase A-catalyzed phosphorylation of smg p21.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222304

2 June 2018

The identification and characterization of a GDP-dissociation inhibitor (GDI) for the CDC42Hs protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222304

2 June 2018

Characterization of the interaction between RhoGDI and Cdc42Hs using fluorescence spectroscopy.

1 reference

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Carboxyl methylation of the low molecular weight GTP-binding protein G25K: regulation of carboxyl methylation by rhoGDI.

1 reference

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Tissue-specific variations in the expression and regulation of the small GTP-binding protein Rho.

1 reference

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27 November 2018

Solubilization of Cdc42Hs from membranes by Rho-GDP dissociation inhibitor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222304

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Measurement of intrinsic nucleotide exchange and GTP hydrolysis rates.

1 reference

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The nucleotide exchange rates of rho and rac small GTP-binding proteins are enhanced to different extents by their regulatory protein Smg GDS

1 reference

https://pubmed.ncbi.nlm.nih.gov/11772396

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inferred from PubMed ID database lookup

Effects of prenyl modifications on interactions of small G proteins with regulators

1 reference

https://pubmed.ncbi.nlm.nih.gov/11772396

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation of Rho GDI stabilizes the Rho A-Rho GDI complex in neutrophil cytosol

1 reference

https://pubmed.ncbi.nlm.nih.gov/11772396

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inferred from PubMed ID database lookup

The Rho small G protein family-Rho GDI system as a temporal and spatial determinant for cytoskeletal control

1 reference

https://pubmed.ncbi.nlm.nih.gov/11772396

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inferred from PubMed ID database lookup

Effect of protein kinase A activity on the association of ADP-ribosylation factor 1 to golgi membranes

1 reference

https://pubmed.ncbi.nlm.nih.gov/11772396

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based on heuristic

inferred from PubMed ID database lookup

Novel phosphorylation of c-ras p21 by protein kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/11772396

12 December 2020

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inferred from PubMed ID database lookup

Phosphoinositide-dependent activation of Rho A involves partial opening of the RhoA/Rho-GDI complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/11772396

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inferred from PubMed ID database lookup

Regulation of Rho protein binding to membranes by rhoGDI: inhibition of releasing activity by physiological ionic conditions

1 reference

https://pubmed.ncbi.nlm.nih.gov/11772396

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Downregulation of phospholipase D by protein kinase A in a cell-free system of human neutrophils

1 reference

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