(Q28364092)

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Neoceptor concept based on molecular complementarity in GPCRs: a mutant adenosine A(3) receptor with selectively enhanced affinity for amine-modified nucleosides

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Neoceptor concept based on molecular complementarity in GPCRs: a mutant adenosine A(3) receptor with selectively enhanced affinity for amine-modified nucleosides (English)

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G protein-coupled receptor

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A Link

7

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author name string

K A Jacobson

1

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Z G Gao

2

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A Chen

3

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D Barak

4

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S A Kim

5

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K Lee

6

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P V Rompaey

8

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S van Calenbergh

9

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B T Liang

10

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publication date

22 November 2001

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Journal of Medicinal Chemistry

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44

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24

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4125-36

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Constitutive activation of A(3) adenosine receptors by site-directed mutagenesis

1 reference

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20 March 2017

Ring-Constrained (N)-methanocarba nucleosides as adenosine receptor agonists: independent 5'-uronamide and 2'-deoxy modifications

1 reference

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20 March 2017

Crystal structure of rhodopsin: A G protein-coupled receptor

1 reference

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20 March 2017

A physiological role of the adenosine A3 receptor: sustained cardioprotection

1 reference

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20 March 2017

Controlling signaling with a specifically designed Gi-coupled receptor

1 reference

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20 March 2017

Hydrophilic side chains in the third and seventh transmembrane helical domains of human A2A adenosine receptors are required for ligand recognition

1 reference

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20 March 2017

Structure-activity relationships of N6-benzyladenosine-5'-uronamides as A3-selective adenosine agonists

1 reference

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20 March 2017

Site-directed mutagenesis identifies residues involved in ligand recognition in the human A2a adenosine receptor

1 reference

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1 reference

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Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium

1 reference

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20 March 2017

Protective effects of adenosine in myocardial ischemia

1 reference

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20 March 2017

GPCRDB: an information system for G protein-coupled receptors

1 reference

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20 March 2017

A3-adenosine receptors: design of selective ligands and therapeutic prospects

1 reference

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29 September 2017

Molecular Architecture of G Protein-Coupled Receptors.

1 reference

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29 September 2017

Ischemic preconditioning Nature's own cardioprotective intervention

1 reference

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29 September 2017

A3 adenosine receptor activation triggers phosphorylation of protein kinase B and protects rat basophilic leukemia 2H3 mast cells from apoptosis.

1 reference

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29 September 2017

Therapeutic potential of adenosine kinase inhibitors

1 reference

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29 September 2017

Site-directed mutagenesis studies of human A(2A) adenosine receptors: involvement of glu(13) and his(278) in ligand binding and sodium modulation

1 reference

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29 September 2017

N6,5'-Disubstituted adenosine derivatives as partial agonists for the human adenosine A3 receptor

1 reference

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29 September 2017

Molecular modeling studies of human A3 adenosine antagonists: structural homology and receptor docking

1 reference

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1 reference

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Direct preconditioning of cultured chick ventricular myocytes. Novel functions of cardiac adenosine A2a and A3 receptors

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125I-4-aminobenzyl-5'-N-methylcarboxamidoadenosine, a high affinity radioligand for the rat A3 adenosine receptor

1 reference

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1 reference

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A1 adenosine receptors. Two amino acids are responsible for species differences in ligand recognition

1 reference

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Adenosine A3 receptor stimulation and cerebral ischemia

1 reference

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29 September 2017

Structure-activity relationships of 9-alkyladenine and ribose-modified adenosine derivatives at rat A3 adenosine receptors

1 reference

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Electrophysiologic effects of dipyridamole on atrioventricular nodal conduction and supraventricular tachycardia. Role of endogenous adenosine

1 reference

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Identification of the adenine binding site of the human A1 adenosine receptor

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N6-cyclopentyl-3'-substituted-xylofuranosyladenosines: a new class of non-xanthine adenosine A1 receptor antagonists

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Site-directed mutagenesis of the human adenosine A2A receptor. Critical involvement of Glu13 in agonist recognition

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10.1021/JM010232O

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