(Q28366017)

2

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L Soceneantu

3

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K J Linton

4

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M Gabriel

5

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C Martin

6

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J Woodhouse

7

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E Blott

8

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C F Higgins

9

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R Callaghan

British Journal of Pharmacology

10

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language of work or name

English

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publication date

December 2001

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published in

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volume

134

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issue

8

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page(s)

1609-18

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cites work

The yeast mitochondrial citrate transport protein. Probing the roles of cysteines, Arg(181), and Arg(189) in transporter function

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

20 March 2017

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ABC Transporters: From Microorganisms to Man

20 March 2017

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In situ biochemical demonstration that P-glycoprotein is a drug efflux pump with broad specificity.

20 March 2017

1 reference

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Cysteine-scanning mutagenesis provides no evidence for the extracellular accessibility of the nucleotide-binding domains of the multidrug resistance transporter P-glycoprotein

29 September 2017

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Ligand-mediated tertiary structure changes of reconstituted P-glycoprotein. A tryptophan fluorescence quenching analysis

29 September 2017

1 reference

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Cys-scanning mutagenesis: a novel approach to structure function relationships in polytopic membrane proteins

29 September 2017

1 reference

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Human P-glycoprotein exhibits reduced affinity for substrates during a catalytic transition state

29 September 2017

1 reference

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Altered drug-stimulated ATPase activity in mutants of the human multidrug resistance protein

29 September 2017

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Clinical trials of agents that reverse multidrug resistance. A literature review

29 September 2017

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Selection of recombinant baculoviruses by visual screening.

29 September 2017

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Efficient inhibition of P-glycoprotein-mediated multidrug resistance with a monoclonal antibody

29 September 2017

1 reference

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Correlation between steady-state ATP hydrolysis and vanadate-induced ADP trapping in Human P-glycoprotein. Evidence for ADP release as the rate-limiting step in the catalytic cycle and its modulation by substrates

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572892

The molecular interaction of the high affinity reversal agent XR9576 with P-glycoprotein

20 June 2018

1 reference

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Structural flexibility of the linker region of human P-glycoprotein permits ATP hydrolysis and drug transport

20 June 2018

1 reference

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The multi-drug resistance reversal agent SR33557 and modulation of vinca alkaloid binding to P-glycoprotein by an allosteric interaction.

20 June 2018

1 reference

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Characterization of the adenosine triphosphatase activity of Chinese hamster P-glycoprotein.

20 June 2018

1 reference

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ATPase activity of purified and reconstituted P-glycoprotein from Chinese hamster ovary cells.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572892

Membrane topology of a cysteine-less mutant of human P-glycoprotein

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572892

P-glycoprotein is stably inhibited by vanadate-induced trapping of nucleotide at a single catalytic site

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572892

Phase I/II trial of dexverapamil plus vinblastine for patients with advanced renal cell carcinoma

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572892

Covalent modification of human P-glycoprotein mutants containing a single cysteine in either nucleotide-binding fold abolishes drug-stimulated ATPase activity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572892

Identification of the multidrug resistance-related membrane glycoprotein as an acceptor for calcium channel blockers.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572892

The alpha 1-adrenergic photoaffinity probe [125I]arylazidoprazosin binds to a specific peptide of P-glycoprotein in multidrug-resistant cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572892

Construction of a functional lactose permease devoid of cysteine residues

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572892

Azidopine noncompetitively interacts with vinblastine and cyclosporin A binding to P-glycoprotein in multidrug resistant cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572892

New Potent Verapamil Derivatives that Reverse Multidrug Resistance in Human Renal Carcinoma Cells and in Transgenic Mice Expressing the Human MDR 1 Gene

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572892

P-glycoprotein possesses a 1,4-dihydropyridine-selective drug acceptor site which is alloserically coupled to a vinca-alkaloid-selective binding site

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572892

Characterization of the azidopine and vinblastine binding site of P-glycoprotein

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572892

Simultaneous analysis of families of sigmoidal curves: application to bioassay, radioligand assay, and physiological dose-response curves

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572892

Cysteines 431 and 1074 are responsible for inhibitory disulfide cross-linking between the two nucleotide-binding sites in human P-glycoprotein

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572892

Identification and localization of three photobinding sites of iodoarylazidoprazosin in hamster P-glycoprotein

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572892

Defining the drug-binding site in the human multidrug resistance P-glycoprotein using a methanethiosulfonate analog of verapamil, MTS-verapamil

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572892

Functional characterization of glycosylation-deficient human P-glycoprotein using a vaccinia virus expression system

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572892

Dissection of drug-binding-induced conformational changes in P-glycoprotein.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572892

Major photoaffinity drug labeling sites for iodoaryl azidoprazosin in P-glycoprotein are within, or immediately C-terminal to, transmembrane domains 6 and 12.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572892

Assay of proteins in the presence of interfering materials

27 November 2018

1 reference

12 December 2020

A method for the determination of inorganic phosphate in the presence of labile organic phosphate and high concentrations of protein: application to lens ATPases

1 reference

12 December 2020

Covalent inhibitors of P-glycoprotein ATPase activity

1 reference

12 December 2020

Histidine 225, a residue of the NhaA-Na+/H+ antiporter of Escherichia coli is exposed and faces the cell exterior

1 reference

12 December 2020

Communication between multiple drug binding sites on P-glycoprotein

1 reference

12 December 2020

Drug binding sites on P-glycoprotein are altered by ATP binding prior to nucleotide hydrolysis

1 reference

12 December 2020

Transmembrane topography of the 100-kDa a subunit (Vph1p) of the yeast vacuolar proton-translocating ATPase

1 reference

12 December 2020

Mechanisms of membrane protein insertion into liposomes during reconstitution procedures involving the use of detergents. 2. Incorporation of the light-driven proton pump bacteriorhodopsin

1 reference

12 December 2020