(Q28368064)

English

Structure-activity and structure-selectivity studies on diaminoquinazolines and other inhibitors of Pneumocystis carinii and Toxoplasma gondii dihydrofolate reductase

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scholarly article

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Structure-activity and structure-selectivity studies on diaminoquinazolines and other inhibitors of Pneumocystis carinii and Toxoplasma gondii dihydrofolate reductase (English)

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Toxoplasma gondii

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Pneumocystis carinii

object named as

Pneumocystis carinii

1 reference

based on heuristic

inferred from title

author name string

A Rosowsky

1

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J B Hynes

2

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S F Queener

3

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language of work or name

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publication date

January 1995

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Antimicrobial Agents and Chemotherapy

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39

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1

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79-86

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Comparison of atovaquone (566C80) with trimethoprim-sulfamethoxazole to treat Pneumocystis carinii pneumonia in patients with AIDS

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=162489

20 March 2017

Activity of bilobalide, a sesquiterpene from Ginkgo biloba, on Pneumocystis carinii

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=162489

20 March 2017

Synergistic combinations of Ro 11-8958 and other dihydrofolate reductase inhibitors with sulfamethoxazole and dapsone for therapy of experimental pneumocystosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=162489

20 March 2017

Identification of highly potent and selective inhibitors of Toxoplasma gondii dihydrofolate reductase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=162489

20 March 2017

Potent antipneumocystis and antitoxoplasma activities of piritrexim, a lipid-soluble antifolate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=162489

20 March 2017

Activity of lipid-soluble inhibitors of dihydrofolate reductase against Pneumocystis carinii in culture and in a rat model of infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=162489

20 March 2017

Efficacy of a hydroxynaphthoquinone, 566C80, in experimental Pneumocystis carinii pneumonitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=162489

20 March 2017

Inhibition of growth of Toxoplasma gondii by qinghaosu and derivatives

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=162489

20 March 2017

Pneumocystis carinii dihydrofolate reductase used to screen potential antipneumocystis drugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=162489

20 March 2017

Susceptibility of Pneumocystis carinii to artemisinin in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=162489

20 March 2017

Suppressive effect of deferoxamine on the growth of Pneumocystis carinii in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=162489

20 March 2017

In vivo activity of the macrolide antibiotics azithromycin, roxithromycin and spiramycin against Toxoplasma gondii

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=162489

20 March 2017

Neurological complications in AIDS.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=162489

29 September 2017

Potent in vitro and in vivo antitoxoplasma activity of the lipid-soluble antifolate trimetrexate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=162489

29 September 2017

Dapsone-trimethoprim for Pneumocystis carinii pneumonia in the acquired immunodeficiency syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=162489

29 September 2017

Problems in the management of opportunistic infections in patients infected with human immunodeficiency virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=162489

29 September 2017

Recent advances in the diagnosis, treatment, and prevention of Pneumocystis carinii pneumonia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=162489

29 September 2017

Pneumocystis carinii, an opportunist in immunocompromised patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=162489

29 September 2017

Evaluation of the efficacy and safety of clindamycin plus pyrimethamine for induction and maintenance therapy of toxoplasmic encephalitis in AIDS.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=162489

29 September 2017

In vitro activities of acridone alkaloids against Pneumocystis carinii

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=162489

29 September 2017

The renewed potential for folate antagonists in contemporary cancer chemotherapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=162489

29 September 2017

Selective inhibition of dihydrofolate reductase from problem human pathogens.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=162489

2 June 2018

Lipophilic antifolates as candidates against opportunistic infections

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=162489

2 June 2018

Synthesis of 5-methyl-5-deaza nonclassical antifolates as inhibitors of dihydrofolate reductases and as potential antipneumocystis, antitoxoplasma, and antitumor agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=162489

2 June 2018

2,4-Diaminothieno[2,3-d]pyrimidine analogues of trimetrexate and piritrexim as potential inhibitors of Pneumocystis carinii and Toxoplasma gondii dihydrofolate reductase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=162489

2 June 2018

Chemical and Biological Studies on 1,2-Dihydro-s-triazines XVIII: Synthesis of 1-(5,6- and 5,'7-Dichloro-2-naphthyl) Derivatives and Related Compounds as Candidate Antimalarial and Antitumor Agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=162489

2 June 2018

Inhibitor binding analysis of dihydrofolate reductases from various species.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=162489

2 June 2018

Treatment of central nervous system toxoplasmosis with pyrimethamine/sulfadiazine combination in 35 patients with the acquired immunodeficiency syndrome. Efficacy of long-term continuous therapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=162489

2 June 2018

Tricyclic 2,4-diaminopyrimidines with broad antifolate activity and the ability to inhibit Pneumocystis carinii growth in cultured human lung fibroblasts in the presence of leucovorin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=162489

2 June 2018

Efficacy of pyrimethamine/sulfadoxine in the prevention of toxoplasmic encephalitis relapses and Pneumocystis carinii pneumonia in HIV-infected patients.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=162489

27 November 2018

Pteridines. 2. New 6,7-disubstituted pteridines as potential antimalarial and antitumor agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=162489

27 November 2018

Aerosolised pentamidine as sole therapy for Pneumocystis carinii pneumonia in patients with acquired immunodeficiency syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/7695334

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pneumocandins from Zalerion arboricola. IV. Biological evaluation of natural and semisynthetic pneumocandins for activity against Pneumocystis carinii and Candida species

1 reference

https://pubmed.ncbi.nlm.nih.gov/7695334

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Salvage trial of trimetrexate-leucovorin for the treatment of cerebral toxoplasmosis in patients with AIDS

1 reference

https://pubmed.ncbi.nlm.nih.gov/7695334

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Safety and efficacy of sulfamethoxazole and trimethoprim chemoprophylaxis for Pneumocystis carinii pneumonia in AIDS

1 reference

https://pubmed.ncbi.nlm.nih.gov/7695334

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of de novo folate synthesis in Pneumocystis carinii and Toxoplasma gondii: potential for screening therapeutic agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/7695334

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clindamycin/primaquine for Pneumocystis carinii pneumonia

1 reference

https://pubmed.ncbi.nlm.nih.gov/7695334

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quinazolines. VI. Synthesis of 2,4-diaminoquinazolines from anthranilonitriles

1 reference

https://pubmed.ncbi.nlm.nih.gov/7695334

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pyrimido(4,5-c)isoquinolines. 2. Synthesis and biological evaluation of some 6-alkyl-,6-aralkyl-, and 6-aryl-1,3-diamino-7,8,9,10-tetrahydropyrimido(4,5-c)isoquinolines as potential folate antagnoists 1

1 reference

https://pubmed.ncbi.nlm.nih.gov/7695334

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pneumocystis carinii Pneumonia: A Comparison Between Patients with the Acquired Immunodeficiency Syndrome and Patients with Other Immunodeficiencies

1 reference

https://pubmed.ncbi.nlm.nih.gov/7695334

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/AAC.39.1.79

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PubMed publication ID

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