(Q28379490)

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Inhibition of phosphodiesterase type IV suppresses human immunodeficiency virus type 1 replication and cytokine production in primary T cells: involvement of NF-kappaB and NFAT

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Inhibition of phosphodiesterase type IV suppresses human immunodeficiency virus type 1 replication and cytokine production in primary T cells: involvement of NF-kappaB and NFAT (English)

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Mª Ángeles Muñoz-Fernández

7

object named as

M A Muñoz-Fernández

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author name string

J Navarro

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C Punzón

2

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J L Jiménez

3

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E Fernández-Cruz

4

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A Pizarro

5

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M Fresno

6

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language of work or name

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publication date

June 1998

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Journal of Virology

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72

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6

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4712-20

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Transcription factors of the NFAT family: regulation and function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109998

20 March 2017

Physical interactions between Ets and NF-kappaB/NFAT proteins play an important role in their cooperative activation of the human immunodeficiency virus enhancer in T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109998

20 March 2017

The T cell activation factor NF-ATc positively regulates HIV-1 replication and gene expression in T cells

1 reference

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20 March 2017

Cyclosporin A sensitivity of the HIV-1 long terminal repeat identifies distinct p56lck-dependent pathways activated by CD4 triggering

1 reference

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20 March 2017

The NF-kappa B and I kappa B proteins: new discoveries and insights

1 reference

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20 March 2017

Pathogenesis of human immunodeficiency virus infection

1 reference

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20 March 2017

NF-AT components define a family of transcription factors targeted in T-cell activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109998

20 March 2017

Multiple cyclic nucleotide phosphodiesterases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109998

20 March 2017

Different members of the Sp1 multigene family exert opposite transcriptional regulation of the long terminal repeat of HIV-1

1 reference

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20 March 2017

Absolute dependence on kappa B responsive elements for initiation and Tat-mediated amplification of HIV transcription in blood CD4 T lymphocytes

1 reference

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20 March 2017

Characterization of antigen receptor response elements within the interleukin-2 enhancer

1 reference

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20 March 2017

Role of SP1-binding domains in in vivo transcriptional regulation of the human immunodeficiency virus type 1 long terminal repeat

1 reference

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20 March 2017

Identification of cis-acting repressive sequences within the negative regulatory element of human immunodeficiency virus type 1

1 reference

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20 March 2017

HIV-1 entry into quiescent primary lymphocytes: molecular analysis reveals a labile, latent viral structure

1 reference

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20 March 2017

Cellular transcription factors involved in the regulation of HIV-1 gene expression

1 reference

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20 March 2017

Specific NF-kappa B subunits act in concert with Tat to stimulate human immunodeficiency virus type 1 transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109998

20 March 2017

A novel Ets-related transcription factor, Elf-1, binds to human immunodeficiency virus type 2 regulatory elements that are required for inducible trans activation in T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109998

20 March 2017

Isolation of the cyclosporin-sensitive T cell transcription factor NFATp

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109998

20 March 2017

Function and activation of NF-kappa B in the immune system

1 reference

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7 April 2017

Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone

1 reference

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7 April 2017

An inducible transcription factor activates expression of human immunodeficiency virus in T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109998

7 April 2017

Tumor necrosis factor alpha and interleukin 1 stimulate the human immunodeficiency virus enhancer by activation of the nuclear factor kappa B

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109998

7 April 2017

Phosphodiesterase (PDE)4 inhibitors: anti-inflammatory drugs of the future?

1 reference

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29 September 2017

Host factors and the pathogenesis of HIV-induced disease

1 reference

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29 September 2017

Interleukin-10-induced HIV-1 expression is mediated by induction of both membrane-bound tumour necrosis factor (TNF)-alpha and TNF receptor type 1 in a promonocytic cell line.

1 reference

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29 September 2017

Immunosuppressive retroviral peptides: cAMP and cytokine patterns

1 reference

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29 September 2017

The specific type IV phosphodiesterase inhibitor rolipram suppresses tumor necrosis factor-alpha production by human mononuclear cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109998

29 September 2017

The c-rel protooncogene product represses NF-kappa B p65-mediated transcriptional activation of the long terminal repeat of type 1 human immunodeficiency virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109998

29 September 2017

Immune modulation in HIV infection: fact or fantasy?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109998

29 September 2017

Regulation of the NF-kappa B/rel transcription factor and I kappa B inhibitor system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109998

29 September 2017

A cooperative interaction between NF-kappa B and Sp1 is required for HIV-1 enhancer activation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109998

29 September 2017

Multifactorial nature of human immunodeficiency virus disease: implications for therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109998

29 September 2017

In vivo footprinting analysis of constitutive and inducible protein-DNA interactions at the long terminal repeat of human immunodeficiency virus type 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109998

29 September 2017

Regulation of human immunodeficiency virus infection: implications for pathogenesis

1 reference

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29 September 2017

Cyclic AMP inhibits phosphatidylinositol-coupled and -uncoupled mitogenic signals in T lymphocytes. Evidence that cAMP alters PKC-induced transcription regulation of members of the jun and fos family of genes.

1 reference

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29 September 2017

Signal transmission between the plasma membrane and nucleus of T lymphocytes

1 reference

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29 September 2017

Pentoxifylline for the treatment of infection with human immunodeficiency virus

1 reference

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29 September 2017

The Th1-Th2 hypothesis of HIV infection: new insights

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109998

29 September 2017

Cytokine modulation of HIV expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109998

29 September 2017

Definition of cis-regulatory elements of the mouse interleukin-5 gene promoter. Involvement of nuclear factor of activated T cell-related factors in interleukin-5 expression

1 reference

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29 September 2017

The antidepressant rolipram suppresses cytokine production and prevents autoimmune encephalomyelitis

1 reference

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29 September 2017

Tumor necrosis factor alpha induces expression of human immunodeficiency virus in a chronically infected T-cell clone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109998

29 September 2017

Tumor necrosis factor alpha activates human immunodeficiency virus type 1 through induction of nuclear factor binding to the NF-kappa B sites in the long terminal repeat

1 reference

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29 September 2017

Tumor necrosis factor alpha induces proteins that bind specifically to kappa B-like enhancer elements and regulate interleukin 2 receptor alpha-chain gene expression in primary human T lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109998

29 September 2017

NF-kappa B: a family of inducible and differentially expressed enhancer-binding proteins in human T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109998

29 September 2017

Activation of the human immunodeficiency virus type 1 enhancer is not dependent on NFAT-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109998

29 September 2017

Inhibition of human immunodeficiency virus and growth of infected T cells by the immunosuppressive drugs cyclosporin A and FK 506

1 reference

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29 September 2017

Replication of human immunodeficiency virus-1 in primary human T cells is dependent on the autocrine secretion of tumor necrosis factor through the control of nuclear factor-kappa B activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109998

2 June 2018

Pentoxifylline inhibits acute HIV-1 replication in human T cells by a mechanism not involving inhibition of tumour necrosis factor synthesis or nuclear factor-kappa B activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109998

2 June 2018

Rolipram, a specific type IV phosphodiesterase inhibitor, is a potent inhibitor of HIV-1 replication.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109998

2 June 2018

ETS family proteins activate transcription from HIV-1 long terminal repeat

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109998

2 June 2018

Interleukin 2 transcription factors as molecular targets of cAMP inhibition: delayed inhibition kinetics and combinatorial transcription roles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109998

2 June 2018

Cyclic AMP inhibits expression of the IL-2 gene through the nuclear factor of activated T cells (NF-AT) site, and transfection of NF-AT cDNAs abrogates the sensitivity of EL-4 cells to cyclic AMP.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109998

2 June 2018

Inhibition of cAMP-responsive element-mediated gene transcription by cyclosporin A and FK506 after membrane depolarization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109998

2 June 2018

Interleukin-10 enhances human immunodeficiency virus type 1 expression in a chronically infected promonocytic cell line (U1) by a tumor necrosis factor alpha-independent mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109998

2 June 2018

Susceptibility of normal human lymphocytes to infection with HTLV-III/LAV.

1 reference

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2 June 2018

HIV enhancer activity perpetuated by NF-kappa B induction on infection of monocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109998

2 June 2018

Tumour necrosis factors (alpha, beta) induced by HIV-1 in peripheral blood mononuclear cells potentiate virus replication.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109998

2 June 2018

Quiescent T lymphocytes as an inducible virus reservoir in HIV-1 infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109998

2 June 2018

Nuclear association of a T-cell transcription factor blocked by FK-506 and cyclosporin A

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109998

2 June 2018

Multiple high-affinity cAMP-phosphodiesterases in human T-lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109998

2 June 2018

Control of T lymphocyte activation and IL-2 receptor expression by endogenously secreted lymphokines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109998

27 November 2018

Interleukin 10 blocks HIV replication in macrophages by inhibiting the autocrine loop of tumor necrosis factor alpha and interleukin 6 induction of virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109998

27 November 2018

In vitro down-regulation of antigen-induced IL-5 gene expression and protein production by cAMP-specific phosphodiesterase type 4 inhibitor

1 reference

https://pubmed.ncbi.nlm.nih.gov/9573235

12 December 2020

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inferred from PubMed ID database lookup

Modulation of antigen- and mitogen-induced proliferative responses of peripheral blood mononuclear cells by nonselective and isozyme selective cyclic nucleotide phosphodiesterase inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/9573235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of mitogen-activated protein kinase kinase kinase reversed cAMP inhibition of NF-kappaB in T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9573235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Physiologic activation of T cells via the T cell receptor induces NF-kappa B

1 reference

https://pubmed.ncbi.nlm.nih.gov/9573235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Assessment of selective inhibition of rat cerebral cortical calcium-independent and calcium-dependent phosphodiesterases in crude extracts using deoxycyclic AMP and potassium ions

1 reference

https://pubmed.ncbi.nlm.nih.gov/9573235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biphasic control of nuclear factor-χB activation by the T cell receptor complex: role of tumor necrosis factor α

1 reference

https://pubmed.ncbi.nlm.nih.gov/9573235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HIV replication in IL-2-stimulated peripheral blood mononuclear cells is driven in an autocrine/paracrine manner by endogenous cytokines

1 reference

https://pubmed.ncbi.nlm.nih.gov/9573235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Up-regulation of monocytic IL-10 by tumor necrosis factor-alpha and cAMP elevating drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/9573235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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