(Q28384799)

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Phosphatase and tensin homolog deleted on chromosome 10 (PTEN) and PH domain and leucine-rich repeat phosphatase cross-talk (PHLPP) in cancer cells and in transforming growth factor β-activated stem cells

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Phosphatase and tensin homolog deleted on chromosome 10 (PTEN) and PH domain and leucine-rich repeat phosphatase cross-talk (PHLPP) in cancer cells and in transforming growth factor β-activated stem cells (English)

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4

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Ulla Stenius

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3

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Johan Högberg

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author name string

Aram Ghalali

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Zhi-Wei Ye

2

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publication date

25 April 2014

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Journal of Biological Chemistry

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289

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17

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11601-15

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Suppression of survival signalling pathways by the phosphatase PHLPP

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002071

20 March 2017

PTEN, NHERF1 and PHLPP form a tumor suppressor network that is disabled in glioblastoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002071

20 March 2017

miR-190-mediated downregulation of PHLPP contributes to arsenic-induced Akt activation and carcinogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002071

20 March 2017

Purinergic receptor-mediated rapid depletion of nuclear phosphorylated Akt depends on pleckstrin homology domain leucine-rich repeat phosphatase, calcineurin, protein phosphatase 2A, and PTEN phosphatases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002071

20 March 2017

Epithelial-mesenchymal transitions in development and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002071

20 March 2017

PTEN inhibits BMI1 function independently of its phosphatase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002071

20 March 2017

TGFbeta in Cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002071

20 March 2017

PtdIns(3,4,5)P(3)-dependent and -independent roles for PTEN in the control of cell migration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002071

20 March 2017

Hedgehog signaling and Bmi-1 regulate self-renewal of normal and malignant human mammary stem cells

1 reference

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20 March 2017

A microRNA expression signature of human solid tumors defines cancer gene targets

1 reference

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20 March 2017

Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation

1 reference

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20 March 2017

Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells

1 reference

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P2X4 and P2X6 receptors associate with VE-cadherin in human endothelial cells

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1 reference

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20 March 2017

MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002071

7 April 2017

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1 reference

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7 April 2017

P2X7 integrates PI3K/AKT and AMPK-PRAS40-mTOR signaling pathways to mediate tumor cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002071

29 September 2017

Histone deacetylase 3 suppression increases PH domain and leucine-rich repeat phosphatase (Phlpp)1 expression in chondrocytes to suppress Akt signaling and matrix secretion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002071

29 September 2017

Naringenin decreases invasiveness and metastasis by inhibiting TGF-β-induced epithelial to mesenchymal transition in pancreatic cancer cells

1 reference

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1 reference

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29 September 2017

Clusterin mediates TGF-β-induced epithelial-mesenchymal transition and metastasis via Twist1 in prostate cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002071

29 September 2017

MiR-26a enhances metastasis potential of lung cancer cells via AKT pathway by targeting PTEN.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002071

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29 September 2017

TGF-β-induced epithelial-mesenchymal transition: a link between cancer and inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002071

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1 reference

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29 September 2017

Akt/PKB-mediated phosphorylation of Twist1 promotes tumor metastasis via mediating cross-talk between PI3K/Akt and TGF-β signaling axes.

1 reference

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Dynamic equilibrium between cancer stem cells and non-stem cancer cells in human SW620 and MCF-7 cancer cell populations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002071

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Increased DNA methyltransferase activity and DNA methylation following Epidermal Growth Factor stimulation in ovarian cancer cells

1 reference

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TGF-β-induced activation of mTOR complex 2 drives epithelial-mesenchymal transition and cell invasion

1 reference

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29 September 2017

Pten loss and RAS/MAPK activation cooperate to promote EMT and metastasis initiated from prostate cancer stem/progenitor cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002071

29 September 2017

Identification of PHLPP1 as a tumor suppressor reveals the role of feedback activation in PTEN-mutant prostate cancer progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002071

29 September 2017

Evi1 forms a bridge between the epigenetic machinery and signaling pathways.

1 reference

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29 September 2017

Purinergic receptors influence the differentiation of human mesenchymal stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002071

29 September 2017

Cell autonomous role of PTEN in regulating castration-resistant prostate cancer growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002071

29 September 2017

microRNA-214 contributes to melanoma tumour progression through suppression of TFAP2C.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002071

29 September 2017

Role of microRNA-214-targeting phosphatase and tensin homolog in advanced glycation end product-induced apoptosis delay in monocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002071

29 September 2017

Costimulation-dependent expression of microRNA-214 increases the ability of T cells to proliferate by targeting Pten.

1 reference

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29 September 2017

Interaction and interrelation of P2X7 and P2X4 receptor complexes in mouse lung epithelial cells

1 reference

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29 September 2017

Mir-214-dependent regulation of the polycomb protein Ezh2 in skeletal muscle and embryonic stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002071

29 September 2017

p85 Associates with unphosphorylated PTEN and the PTEN-associated complex.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002071

29 September 2017

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1 reference

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29 September 2017

Tenets of PTEN tumor suppression

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002071

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Regulation of cancer cell survival, migration, and invasion by Twist: AKT2 comes to interplay

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Signaling pathways in cancer and embryonic stem cells

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002071

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Activation of PI3K-Akt signaling pathway promotes prostate cancer cell invasion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002071

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Dietary sphingolipids suppress a subset of preneoplastic rat liver lesions exhibiting high PTEN, low phospho-Akt and high levels of ceramide species

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Bmi-1 is a crucial regulator of prostate stem cell self-renewal and malignant transformation

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002071

2 June 2018

Regulation of PTEN activity by its carboxyl-terminal autoinhibitory domain

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Dose response of hepatocyte replication in rats following continuous exposure to diethylnitrosamine.

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2 June 2018

Evi1 represses PTEN expression and activates PI3K/AKT/mTOR via interactions with polycomb proteins.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M113.537241

21 January 2018

Cellular distributions of molecules with altered expression specific to the tumor promotion process from the early stage in a rat two-stage hepatocarcinogenesis model

1 reference

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21 January 2018

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1 reference

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12 December 2020

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10.1074/JBC.M113.537241

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