(Q28390091)

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Proteasome dysfunction in Drosophila signals to an Nrf2-dependent regulatory circuit aiming to restore proteostasis and prevent premature aging

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

25 June 2017

Proteasome dysfunction in Drosophila signals to an Nrf2-dependent regulatory circuit aiming to restore proteostasis and prevent premature aging (English)

1 reference

Europe PubMed Central

PubMed publication ID

25 June 2017

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Gerasimos P Sykiotis

object named as

Gerasimos P Sykiotis

2

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Athanasios Dimopoulos

object named as

Meletios A Dimopoulos

5

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author name string

Eleni N Tsakiri

1

1 reference

Europe PubMed Central

PubMed publication ID

25 June 2017

Issidora S Papassideri

3

1 reference

Europe PubMed Central

PubMed publication ID

25 June 2017

Evangelos Terpos

4

1 reference

Europe PubMed Central

PubMed publication ID

25 June 2017

Vassilis G Gorgoulis

6

1 reference

Europe PubMed Central

PubMed publication ID

25 June 2017

Dirk Bohmann

7

1 reference

Europe PubMed Central

PubMed publication ID

25 June 2017

Ioannis P Trougakos

8

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Europe PubMed Central

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25 June 2017

language of work or name

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publication date

28 June 2013

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Europe PubMed Central

PubMed publication ID

25 June 2017

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Europe PubMed Central

PubMed publication ID

25 June 2017

12

1 reference

Europe PubMed Central

PubMed publication ID

25 June 2017

5

1 reference

Europe PubMed Central

PubMed publication ID

25 June 2017

802-813

1 reference

Europe PubMed Central

PubMed publication ID

25 June 2017

Stress-activated cap'n'collar transcription factors in aging and human disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4096703

20 March 2017

Collapse of proteostasis represents an early molecular event in Caenorhabditis elegans aging

1 reference

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20 March 2017

A mouse model of ATR-Seckel shows embryonic replicative stress and accelerated aging

1 reference

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20 March 2017

PGAM5 tethers a ternary complex containing Keap1 and Nrf2 to mitochondria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4096703

20 March 2017

Vacuolar leukoencephalopathy with widespread astrogliosis in mice lacking transcription factor Nrf2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4096703

20 March 2017

Biological and chemical approaches to diseases of proteostasis deficiency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4096703

7 April 2017

Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4096703

7 April 2017

Direct inhibition of the longevity-promoting factor SKN-1 by insulin-like signaling in C. elegans

1 reference

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7 April 2017

Understanding the odd science of aging

1 reference

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7 April 2017

Declining signal dependence of Nrf2-MafS-regulated gene expression correlates with aging phenotypes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4096703

29 September 2017

Non-enzymatic post-translational protein modifications and proteostasis network deregulation in carcinogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4096703

29 September 2017

Differential regulation of proteasome functionality in reproductive vs. somatic tissues of Drosophila during aging or oxidative stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4096703

29 September 2017

NRF2 and cancer: the good, the bad and the importance of context.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4096703

29 September 2017

Nrf2-dependent induction of proteasome and Pa28αβ regulator are required for adaptation to oxidative stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4096703

29 September 2017

Protein oxidative modification in the aging organism and the role of the ubiquitin proteasomal system.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4096703

29 September 2017

Mitochondrial quality control by the ubiquitin-proteasome system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4096703

29 September 2017

Elevated proteasome capacity extends replicative lifespan in Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4096703

29 September 2017

Novel proteasome inhibitors to overcome bortezomib resistance

1 reference

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Cellular stress response pathways and ageing: intricate molecular relationships

1 reference

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29 September 2017

Selective autophagy in the maintenance of cellular homeostasis in aging organisms

1 reference

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29 September 2017

RNAi screen of the druggable genome identifies modulators of proteasome inhibitor sensitivity in myeloma including CDK5.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4096703

29 September 2017

Basic leucine zipper protein Cnc-C is a substrate and transcriptional regulator of the Drosophila 26S proteasome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4096703

29 September 2017

Biomarkers of aging in Drosophila

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4096703

29 September 2017

Building on bortezomib: second-generation proteasome inhibitors as anti-cancer therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4096703

29 September 2017

The 26 S proteasome: from basic mechanisms to drug targeting

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4096703

29 September 2017

Insights into the molecular architecture of the 26S proteasome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4096703

29 September 2017

Tiron, a ROS scavenger, protects human lung cancer Calu-6 cells against antimycin A-induced cell death.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4096703

29 September 2017

Regulation of proteasome-mediated protein degradation during oxidative stress and aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4096703

29 September 2017

Keap1/Nrf2 signaling regulates oxidative stress tolerance and lifespan in Drosophila

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4096703

29 September 2017

Sir2p-dependent protein segregation gives rise to a superior reactive oxygen species management in the progeny of Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4096703

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Common aging pathways in worms, flies, mice and humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4096703

29 September 2017

Aging perturbs 26S proteasome assembly in Drosophila melanogaster

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4096703

29 September 2017

Alteration of Drosophila life span using conditional, tissue-specific expression of transgenes triggered by doxycyline or RU486/Mifepristone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4096703

29 September 2017

The pharmacology of ageing in Drosophila

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4096703

29 September 2017

Central role of the proteasome in senescence and survival of human fibroblasts: induction of a senescence-like phenotype upon its inhibition and resistance to stress upon its activation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4096703

29 September 2017

Impairment of proteasome structure and function in aging.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4096703

29 September 2017

Analysis of Drosophila 26 S proteasome using RNA interference

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4096703

29 September 2017

Identification and characterization of a Drosophila proteasome regulatory network

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4096703

2 June 2018

Cap 'n' collar B cooperates with a small Maf subunit to specify pharyngeal development and suppress deformed homeotic function in the Drosophila head.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4096703

2 June 2018

Subunit compositions and catalytic properties of proteasomes from developmental temperature- sensitive mutants of Drosophila melanogaster.

1 reference

https://api.crossref.org/works/10.1111%2FACEL.12111

21 January 2018

Age-associated decline in mitochondrial respiration and electron transport in Drosophila melanogaster

1 reference

https://api.crossref.org/works/10.1111%2FACEL.12111

21 January 2018

Effects of aging and reproduction on protein quality control in soma and gametes of Drosophila melanogaster

1 reference

https://api.crossref.org/works/10.1111%2FACEL.12111

21 January 2018

Carbonylated proteins are eliminated during reproduction in C. elegans

1 reference

https://api.crossref.org/works/10.1111%2FACEL.12111

21 January 2018

Functional interplay between mitochondrial and proteasome activity in skin aging.

1 reference

https://api.crossref.org/works/10.1111%2FACEL.12111

21 January 2018

Deletion of proteasomal subunit S5a/Rpn10/p54 causes lethality, multiple mitotic defects and overexpression of proteasomal genes in Drosophila melanogaster

1 reference

https://api.crossref.org/works/10.1111%2FACEL.12111

21 January 2018

Genetic evidence linking age-dependent attenuation of the 26S proteasome with the aging process

1 reference

https://api.crossref.org/works/10.1111%2FACEL.12111

21 January 2018

RPN-6 determines C. elegans longevity under proteotoxic stress conditions

1 reference

https://api.crossref.org/works/10.1111%2FACEL.12111

21 January 2018

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4096703

27 November 2018

The function of hypoxia-inducible factor 1 (HIF-1) is impaired in senescent mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/23738891

12 December 2020

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10.1111/ACEL.12111

1 reference

Europe PubMed Central

PubMed publication ID

25 June 2017

OpenCitations bibliographic resource ID

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Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PMC publication ID

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Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

25 June 2017

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