(Q34801742)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12200039%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

review article

1 reference

title

Impairment of proteasome structure and function in aging (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12200039%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12200039%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

Bertrand Friguet

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12200039%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

author name string

Géraldine Carrard

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12200039%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

Anne-Laure Bulteau

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12200039%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

publication date

1 November 2002

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12200039%20AND%20SRC:MED&resulttype=core&format=json

International Journal of Biochemistry & Cell Biology

12 November 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12200039%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

volume

34

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12200039%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

issue

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12200039%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

page(s)

1461-1474

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12200039%20AND%20SRC:MED&resulttype=core&format=json

Protein oxidation in aging, disease, and oxidative stress

12 November 2019

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7 January 2021

The free radical theory of aging matures

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7 January 2021

Protein oxidation and aging

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7 January 2021

Parkinson's disease, pesticides and mitochondrial dysfunction

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7 January 2021

Structure and functions of the 20S and 26S proteasomes

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7 January 2021

Degradation of oxidized proteins in mammalian cells.

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7 January 2021

The 26S proteasome: a molecular machine designed for controlled proteolysis

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7 January 2021

Muscle protein breakdown and the critical role of the ubiquitin-proteasome pathway in normal and disease states

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7 January 2021

Review of alterations of the cyclin-dependent kinase inhibitor INK4 family genes p15, p16, p18 and p19 in human leukemia-lymphoma cells

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7 January 2021

How proteolysis drives the cell cycle

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7 January 2021

Regulation of cell proliferation by the E2F transcription factors

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7 January 2021

The 19S complex of the proteasome regulates nucleotide excision repair in yeast.

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7 January 2021

The proteasome in cancer biology and treatment

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7 January 2021

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7 January 2021

20S proteasome biogenesis

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7 January 2021

Size and shape of the multicatalytic proteinase from rat skeletal muscle

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7 January 2021

The three-dimensional structure of proteasomes from Thermoplasma acidophilum as determined by electron microscopy using random conical tilting

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7 January 2021

Crystal structure of the 20S proteasome from the archaeon T. acidophilum at 3.4 A resolution

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7 January 2021

Molecular characterization of the "26S" proteasome complex from rat liver.

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7 January 2021

Primary structure of the Thermoplasma proteasome and its implications for the structure, function, and evolution of the multicatalytic proteinase

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7 January 2021

Phylogenic relationships of the amino acid sequences of prosome (proteasome, MCP) subunits

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7 January 2021

Structure of 20S proteasome from yeast at 2.4 A resolution

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7 January 2021

Ump1p is required for proper maturation of the 20S proteasome and becomes its substrate upon completion of the assembly.

1 reference

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7 January 2021

Eukaryotic 20S proteasome catalytic subunit propeptides prevent active site inactivation by N-terminal acetylation and promote particle assembly

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https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

Caretaker or undertaker? The role of the proteasome in aging

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

A protein catalytic framework with an N-terminal nucleophile is capable of self-activation

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

Proteasome from Thermoplasma acidophilum: a threonine protease

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

Autocatalytic processing of the 20S proteasome

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

Autocatalytic subunit processing couples active site formation in the 20S proteasome to completion of assembly

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

Proteasome active sites allosterically regulate each other, suggesting a cyclical bite-chew mechanism for protein breakdown

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

Evidence for the presence of five distinct proteolytic components in the pituitary multicatalytic proteinase complex. Properties of two components cleaving bonds on the carboxyl side of branched chain and small neutral amino acids

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

Tripeptidyl peptidases: enzymes that count

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

Selective inhibitors of the proteasome-dependent and vacuolar pathways of protein degradation in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

Lactacystin and clasto-lactacystin beta-lactone modify multiple proteasome beta-subunits and inhibit intracellular protein degradation and major histocompatibility complex class I antigen presentation

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

Epoxomicin, a potent and selective proteasome inhibitor, exhibits in vivo antiinflammatory activity

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

Mechanistic studies on the inactivation of the proteasome by lactacystin: a central role for clasto-lactacystin beta-lactone

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

Inhibition of proteasome activities and subunit-specific amino-terminal threonine modification by lactacystin

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

Kinetic characterization of the chymotryptic activity of the 20S proteasome.

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

Lactacystin, a specific inhibitor of the proteasome, inhibits human platelet lysosomal cathepsin A-like enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

A giant protease with potential to substitute for some functions of the proteasome

1 reference

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7 January 2021

The secondary fungal metabolite gliotoxin targets proteolytic activities of the proteasome

1 reference

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7 January 2021

Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

The proteasome pathway is required for cytokine-induced endothelial-leukocyte adhesion molecule expression

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

Specificities of cell permeant peptidyl inhibitors for the proteinase activities of mu-calpain and the 20 S proteasome

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

Potent and selective inhibitors of the proteasome: dipeptidyl boronic acids

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

Characterization of peptidyl boronic acid inhibitors of mammalian 20 S and 26 S proteasomes and their inhibition of proteasomes in cultured cells

1 reference

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7 January 2021

Covalent modification of the active site threonine of proteasomal beta subunits and the Escherichia coli homolog HslV by a new class of inhibitors

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7 January 2021

Proteasome inhibitors: from research tools to drug candidates

1 reference

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7 January 2021

A gated channel into the proteasome core particle

1 reference

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7 January 2021

The axial channel of the proteasome core particle is gated by the Rpt2 ATPase and controls both substrate entry and product release

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

Structural basis for the activation of 20S proteasomes by 11S regulators

1 reference

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7 January 2021

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

1 reference

7 January 2021

The base of the proteasome regulatory particle exhibits chaperone-like activity

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

Functional analysis of the proteasome regulatory particle

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

Antigen processing by the proteasome

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

The multiubiquitin-chain-binding protein Mcb1 is a component of the 26S proteasome in Saccharomyces cerevisiae and plays a nonessential, substrate-specific role in protein turnover.

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

Purification and characterization of a protein inhibitor of the 20S proteasome (macropain)

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

Primary structures of two homologous subunits of PA28, a gamma-interferon-inducible protein activator of the 20S proteasome

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

Impaired immunoproteasome assembly and immune responses in PA28-/- mice.

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

The proteasome activator 11 S REG (PA28) and class I antigen presentation

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

Hybrid proteasomes. Induction by interferon-gamma and contribution to ATP-dependent proteolysis

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

Replacement of proteasome subunits X and Y by LMP7 and LMP2 induced by interferon-gamma for acquirement of the functional diversity responsible for antigen processing

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

Proteasome and class I antigen processing and presentation

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

Newly identified pair of proteasomal subunits regulated reciprocally by interferon gamma

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

Gamma-interferon and expression of MHC genes regulate peptide hydrolysis by proteasomes

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

Themes and variations on ubiquitylation

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

Reactive oxygen species, antioxidants, and the mammalian thioredoxin system

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

Thioredoxin reductase - its role in epidermal redox status

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

Free radicals and disease

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

Susceptibility of glucose-6-phosphate dehydrogenase modified by 4-hydroxy-2-nonenal and metal-catalyzed oxidation to proteolysis by the multicatalytic protease.

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

Selective degradation of oxidized calmodulin by the 20 S proteasome

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

1 reference

7 January 2021

Helical peptide models for protein glycation: proximity effects in catalysis of the Amadori rearrangement

1 reference

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7 January 2021

End-stage renal disease and diabetes catalyze the formation of a pentose-derived crosslink from aging human collagen

1 reference

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7 January 2021

High correlation between pentosidine protein crosslinks and pigmentation implicates ascorbate oxidation in human lens senescence and cataractogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

On the "struggle between chemistry and biology during aging"--implications for DNA repair, apoptosis and proteolysis, and a novel route of intervention

1 reference

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7 January 2021

Carbonyl assays for determination of oxidatively modified proteins.

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

Increase of oxidatively modified protein is associated with a decrease of proteasome activity and content in aging epidermal cells

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

Oxidative modification of proteins during aging

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

Proteasome inhibition by lipofuscin/ceroid during postmitotic aging of fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

Impaired proteasome function in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

Oxidative damage during aging targets mitochondrial aconitase

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

Mitochondrial adenine nucleotide translocase is modified oxidatively during aging

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

Oxidative stress and recovery from oxidative stress are associated with altered ubiquitin conjugating and proteolytic activities in bovine lens epithelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

Removal of oxidatively damaged proteins from lens cells by the ubiquitin-proteasome pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

4-Hydroxy-2-nonenal-mediated impairment of intracellular proteolysis during oxidative stress. Identification of proteasomes as target molecules

1 reference

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7 January 2021

Degradation of oxidized proteins by the 20S proteasome.

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

Basic Medical Research Award. The ubiquitin system

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

1 reference

7 January 2021

Mechanisms underlying ubiquitination

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

Alteration of rat liver 20S proteasome activities by age and food restriction.

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

Dietary self-selection can compensate an age-related decrease of rat liver 20 S proteasome activity observed with standard diet

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

Decreased proteasome-mediated degradation in T cells from the elderly: A role in immune senescence

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

Possible involvement of proteasome inhibition in aging: implications for oxidative stress.

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

Aging and proteolysis of oxidized proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

Proteasomes and proteasome inhibition in the central nervous system

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

When lysosomes get old.

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

Dietary restriction initiated in late adulthood can reverse age-related alterations of protein and protein metabolism

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

Mitotic misregulation and human aging

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

Gene expression profile of aging and its retardation by caloric restriction

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

Age-dependent declines in proteasome activity in the heart

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

Hydrogen peroxide-mediated protein oxidation in young and old human MRC-5 fibroblasts.

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

Fibroblast cultures from healthy centenarians have an active proteasome

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

Protection from oxidative inactivation of the 20S proteasome by heat-shock protein 90.

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

Comparative resistance of the 20S and 26S proteasome to oxidative stress.

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

Activation of the Cell Death Program by Nitric Oxide Involves Inhibition of the Proteasome

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

Proteasome inactivation upon aging and on oxidation-effect of HSP 90

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

Oxidative stress-associated impairment of proteasome activity during ischemia-reperfusion injury

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

Inhibition of the multicatalytic proteinase (proteasome) by 4-hydroxy-2-nonenal cross-linked protein

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

Reduced ubiquitin-dependent degradation of c-Jun after phosphorylation by MAP kinases

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

Ca2+-free calmodulin and calmodulin damaged by in vitro aging are selectively degraded by 26 S proteasomes without ubiquitination.

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

Different mechanisms control signal-induced degradation and basal turnover of the NF-kappaB inhibitor IkappaB alpha in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

Ornithine decarboxylase is degraded by the 26S proteasome without ubiquitination

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

Degradation of tyrosine aminotransferase (TAT) via the ubiquitin-proteasome pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900085-7

7 January 2021

10.1016/S1357-2725(02)00085-7

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12200039%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

1 reference