(Q28390800)

2

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Lori Zacharoff

3

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Michael Wedel

4

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Wuming Gong

5

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Dinesh K Deelchand

6

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Tongbin Li

7

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Janet M Dubinsky

Journal of Cerebral Blood Flow & Metabolism

8

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language of work or name

English

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publication date

November 2012

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published in

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volume

32

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issue

11

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page(s)

1977-88

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cites work

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The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription

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Cytosolic phosphorylation potential

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Long glutamine tracts cause nuclear localization of a novel form of huntingtin in medium spiny striatal neurons in HdhQ92 and HdhQ111 knock-in mice

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The taurine transporter: mechanisms of regulation

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Involvement of mitochondrial complex II defects in neuronal death produced by N-terminus fragment of mutated huntingtin

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Effects of CAG repeat length, HTT protein length and protein context on cerebral metabolism measured using magnetic resonance spectroscopy in transgenic mouse models of Huntington's disease

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Sp1 and TAFII130 transcriptional activity disrupted in early Huntington's disease

29 September 2017

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Characterization of cerebral glucose dynamics in vivo with a four-state conformational model of transport at the blood-brain barrier.

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Mitochondrial sensitivity and altered calcium handling underlie enhanced NMDA-induced apoptosis in YAC128 model of Huntington's disease.

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Specific progressive cAMP reduction implicates energy deficit in presymptomatic Huntington's disease knock-in mice

21 January 2018

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In vivo assessment of free magnesium concentration in human brain by 31P MRS. A new calibration curve based on a mathematical algorithm.

21 January 2018

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The integration of cell and chemical biology in protein folding

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Mitochondrial respiration and ATP production are significantly impaired in striatal cells expressing mutant huntingtin

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Abnormal response to cortical activation in early stages of Huntington disease

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Increased glucose metabolism and ATP level in brain tissue of Huntington's disease transgenic mice

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Mitochondrial dysfunction in Huntington's disease: the bioenergetics of isolated and in situ mitochondria from transgenic mice

21 January 2018

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HD CAG repeat implicates a dominant property of huntingtin in mitochondrial energy metabolism

21 January 2018

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Inhibition of polyglutamine aggregation in R6/2 HD brain slices-complex dose-response profiles

21 January 2018

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Metabolic characterization of the R6/2 transgenic mouse model of Huntington's disease by high-resolution MAS 1H NMR spectroscopy

21 January 2018

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Early phenotypes that presage late-onset neurodegenerative disease allow testing of modifiers in Hdh CAG knock-in mice

21 January 2018

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Relationship between intracellular pH and energy metabolism in dog brain as measured by 31P-NMR

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12 December 2020

Adenosinetriphosphate-creatine transphosphorylase. III. Kinetic studies

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12 December 2020

Discovery of bioactive small-molecule inhibitor of poly adp-ribose polymerase: implications for energy-deficient cells

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12 December 2020

Natural osmolytes remodel the aggregation pathway of mutant huntingtin exon 1

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12 December 2020