(Q28391958)

English

Non-additive hepatic gene expression elicited by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and 2,2',4,4',5,5'-hexachlorobiphenyl (PCB153) co-treatment in C57BL/6 mice

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Non-additive hepatic gene expression elicited by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and 2,2',4,4',5,5'-hexachlorobiphenyl (PCB153) co-treatment in C57BL/6 mice (English)

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object named as

Sarah E Reese

5

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Lyle D. Burgoon

object named as

Lyle D Burgoon

4

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Kellie J Archer

object named as

Kellie J Archer

6

1 reference

ORCID Public Data File 2021

author name string

Anna K Kopec

1

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Michelle L D'Souza

2

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Bryan D Mets

3

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Dave Potter

7

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Colleen Tashiro

8

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Bonnie Sharratt

9

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Jack R Harkema

10

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Timothy R Zacharewski

11

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language of work or name

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publication date

15 October 2011

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Toxicology and Applied Pharmacology

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256

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154-67

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2

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Introducing the "TCDD-inducible AhR-Nrf2 gene battery"

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126514

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1 reference

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20 March 2017

SerpinB6 is an inhibitor of kallikrein-8 in keratinocytes

1 reference

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20 March 2017

Phosphoinositides in cell regulation and membrane dynamics

1 reference

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20 March 2017

The 2005 World Health Organization reevaluation of human and Mammalian toxic equivalency factors for dioxins and dioxin-like compounds

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126514

20 March 2017

Protocols for the assurance of microarray data quality and process control

1 reference

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20 March 2017

Aryl hydrocarbon receptor regulates distinct dioxin-dependent and dioxin-independent gene batteries

1 reference

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20 March 2017

Highly chlorinated PCBs inhibit the human xenobiotic response mediated by the steroid and xenobiotic receptor (SXR).

1 reference

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20 March 2017

Intracellular serpin SERPINB6 (PI6) is abundantly expressed by human mast cells and forms complexes with beta-tryptase monomers

1 reference

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20 March 2017

Induction of murine NAD(P)H:quinone oxidoreductase by 2,3,7,8-tetrachlorodibenzo-p-dioxin requires the CNC (cap n collar) basic leucine zipper transcription factor Nrf2 (nuclear factor erythroid 2-related factor 2)

1 reference

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20 March 2017

DAVID: Database for Annotation, Visualization, and Integrated Discovery

1 reference

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20 March 2017

Ligand binding and activation of the Ah receptor

1 reference

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20 March 2017

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1 reference

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20 March 2017

Cloning and recombinant expression of a structurally novel human secreted phospholipase A2

1 reference

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20 March 2017

Role of the aromatic hydrocarbon receptor and [Ah] gene battery in the oxidative stress response, cell cycle control, and apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126514

20 March 2017

Effects of CYP1A2 on disposition of 2,3,7, 8-tetrachlorodibenzo-p-dioxin, 2,3,4,7,8-pentachlorodibenzofuran, and 2,2',4,4',5,5'-hexachlorobiphenyl in CYP1A2 knockout and parental (C57BL/6N and 129/Sv) strains of mice

1 reference

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20 March 2017

Polychlorinated biphenyls (PCBs): environmental impact, biochemical and toxic responses, and implications for risk assessment

1 reference

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7 April 2017

2,3,7,8-Tetrachlorodibenzo-p-Dioxin and Related Halogenated Aromatic Hydrocarbons: Examination of the Mechanism of Toxicity

1 reference

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7 April 2017

Differences in TCDD-elicited gene expression profiles in human HepG2, mouse Hepa1c1c7 and rat H4IIE hepatoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126514

29 September 2017

Genome-wide computational analysis of dioxin response element location and distribution in the human, mouse, and rat genomes

1 reference

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29 September 2017

Identification of the aryl hydrocarbon receptor target gene TiPARP as a mediator of suppression of hepatic gluconeogenesis by 2,3,7,8-tetrachlorodibenzo-p-dioxin and of nicotinamide as a corrective agent for this effect

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126514

29 September 2017

Automated dose-response analysis and comparative toxicogenomic evaluation of the hepatic effects elicited by TCDD, TCDF, and PCB126 in C57BL/6 mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126514

29 September 2017

The activated aryl hydrocarbon receptor synergizes mitogen-induced murine liver hyperplasia

1 reference

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29 September 2017

A functional cross-talk between liver X receptor-α and constitutive androstane receptor links lipogenesis and xenobiotic responses

1 reference

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29 September 2017

TNF suppresses acute intestinal inflammation by inducing local glucocorticoid synthesis

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29 September 2017

Inflammasome up-regulation and activation in dysferlin-deficient skeletal muscle

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29 September 2017

PCB-153 exposure coordinates cell cycle progression and cellular metabolism in human mammary epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126514

29 September 2017

Hepatic gene expression profile in mice perorally infected with Echinococcus multilocularis eggs

1 reference

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29 September 2017

A novel role for the dioxin receptor in fatty acid metabolism and hepatic steatosis

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29 September 2017

Nrf2 the rescue: effects of the antioxidative/electrophilic response on the liver

1 reference

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29 September 2017

PCB153-elicited hepatic responses in the immature, ovariectomized C57BL/6 mice: comparative toxicogenomic effects of dioxin and non-dioxin-like ligands

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126514

29 September 2017

Deglutathionylation of 2-Cys peroxiredoxin is specifically catalyzed by sulfiredoxin

1 reference

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29 September 2017

Phenobarbital elicits unique, early changes in the expression of hepatic genes that affect critical pathways in tumor-prone B6C3F1 mice

1 reference

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29 September 2017

Nrf2-dependent sulfiredoxin-1 expression protects against cigarette smoke-induced oxidative stress in lungs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126514

29 September 2017

Deletion of ELOVL5 leads to fatty liver through activation of SREBP-1c in mice

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29 September 2017

Gene expression in human NAFLD.

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29 September 2017

Tip30-induced apoptosis requires translocation of Bax and involves mitochondrial release of cytochrome c and Smac/DIABLO in hepatocellular carcinoma cells

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29 September 2017

Binary PAH mixtures cause additive or antagonistic effects on gene expression but synergistic effects on DNA adduct formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126514

29 September 2017

Discovery of a highly active ligand of human pregnane x receptor: a case study from pharmacophore modeling and virtual screening to "in vivo" biological activity.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126514

29 September 2017

dbZach toxicogenomic information management system

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29 September 2017

Predicting interactions from mechanistic information: can omic data validate theories?

1 reference

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29 September 2017

Carcinogenicity of "non-dioxinlike" polychlorinated biphenyls

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126514

29 September 2017

Comparative toxicogenomic analysis of the hepatotoxic effects of TCDD in Sprague Dawley rats and C57BL/6 mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126514

29 September 2017

NTP technical report on the toxicology and carcinogenesis studies of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) (CAS No. 1746-01-6) in female Harlan Sprague-Dawley rats (Gavage Studies).

1 reference

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29 September 2017

Empirical bayes gene screening tool for time-course or dose-response microarray data

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29 September 2017

Comparative analysis of dioxin response elements in human, mouse and rat genomic sequences.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126514

29 September 2017

Hepatic insig-1 or -2 overexpression reduces lipogenesis in obese Zucker diabetic fatty rats and in fasted/refed normal rats

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29 September 2017

Drug-activated nuclear receptors CAR and PXR.

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29 September 2017

Antagonism of aryl hydrocarbon receptor-dependent induction of CYP1A1 and inhibition of IgM expression by di-ortho-substituted polychlorinated biphenyls

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29 September 2017

Cellular arachidonate-releasing function of novel classes of secretory phospholipase A2s (groups III and XII).

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29 September 2017

Roles of the stress-induced gene IEX-1 in regulation of cell death and oncogenesis

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29 September 2017

Molecular biology of the Ah receptor and its role in carcinogenesis

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126514

29 September 2017

Induction of drug metabolism by nuclear receptor CAR: molecular mechanisms and implications for drug research

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126514

29 September 2017

c-Myc target genes involved in cell growth, apoptosis, and metabolism

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29 September 2017

Synergistic effect of 2,2',4,4',5,5'-hexachlorobiphenyl and 2,3,7,8-tetrachlorodibenzo-p-dioxin on hepatic porphyrin levels in the rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126514

29 September 2017

Tumor necrosis factor: a pleiotropic cytokine and therapeutic target

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29 September 2017

Polychlorinated biphenyl levels in the tissues of exposed and nonexposed humans

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29 September 2017

Polychlorinated biphenyls (PCBs) and human health: an update

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126514

29 September 2017

Cellular responses to oxidative stress: the [Ah] gene battery as a paradigm

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126514

29 September 2017

Polychlorinated biphenyls (PCBs), dibenzo-p-dioxins (PCDDs), dibenzofurans (PCDFs), and related compounds: environmental and mechanistic considerations which support the development of toxic equivalency factors (TEFs).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126514

29 September 2017

Temporal and dose-dependent hepatic gene expression patterns in mice provide new insights into TCDD-Mediated hepatotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126514

2 June 2018

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1 reference

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2 June 2018

Limitations of the toxic equivalency factor approach for risk assessment of TCDD and related compounds

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126514

2 June 2018

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1 reference

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2 June 2018

Studies on the mechanism of toxicity of the chlorinated dibenzo-p-dioxins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126514

2 June 2018

Synthesis, biologic and toxic effects of the major 2,3,7,8-tetrachlorodibenzo-p-dioxin metabolites in the rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126514

2 June 2018

2,2',4,4',5,5'-hexachlorobiphenyl as a 2,3,7,8-tetrachlorodibenzo-p-dioxin antagonist in C57BL/6J mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126514

2 June 2018

2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) reverses hyperglycemia in a type II diabetes mellitus rat model by a mechanism unrelated to PPAR gamma

1 reference

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27 November 2018

Chemotherapy-induced apoptosis in hepatocellular carcinoma involves the p53 family and is mediated via the extrinsic and the intrinsic pathway

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27 November 2018

The aldo-keto reductase Akr1b7 gene is a common transcriptional target of xenobiotic receptors pregnane X receptor and constitutive androstane receptor

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27 November 2018

Regulatory cross-talk between drug metabolism and lipid homeostasis: constitutive androstane receptor and pregnane X receptor increase Insig-1 expression

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27 November 2018

Comparative toxicogenomic examination of the hepatic effects of PCB126 and TCDD in immature, ovariectomized C57BL/6 mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126514

27 November 2018

Toxicology and carcinogenesis studies of a binary mixture of 3,3',4,4',5-pentachlorobiphenyl (PCB 126) (Cas No. 57465-28-8) and 2,2',4,4',5,5'-hexachlorobiphenyl (PCB 153) (CAS No. 35065-27-1) in female Harlan Sprague-Dawley rats (gavage studies).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126514

27 November 2018

NTP technical report on the toxicology and carcinogenesis studies of 2,2',4,4',5,5'-hexachlorobiphenyl (PCB 153) (CAS No. 35065-27-1) in female Harlan Sprague-Dawley rats (Gavage studies).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126514

27 November 2018

NTP toxicology and carcinogenesis studies of 3,3',4,4',5-pentachlorobiphenyl (PCB 126) (CAS No. 57465-28-8) in female Harlan Sprague-Dawley rats (Gavage Studies).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126514

27 November 2018

Enzymatic properties of a member (AKR1C20) of the aldo-keto reductase family

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27 November 2018

Phosphatidylcholine homeostasis and liver failure

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27 November 2018

Normalization of two-channel microarray experiments: a semiparametric approach.

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27 November 2018

Effect of 2,2',4,4',5,5'-hexachlorobiphenyl (PCB-153) on hepatocyte proliferation and apoptosis in mice deficient in the p50 subunit of the transcription factor NF-kappaB.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126514

27 November 2018

Nuclear pregnane x receptor and constitutive androstane receptor regulate overlapping but distinct sets of genes involved in xenobiotic detoxification

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126514

27 November 2018

Comparative responsiveness of hypothyroxinemia and hepatic enzyme induction in Long-Evans rats versus C57BL/6J mice exposed to TCDD-like and phenobarbital-like polychlorinated biphenyl congeners

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126514

27 November 2018

Regulation of cell proliferation, apoptosis, and transcription factor activities during the promotion of liver carcinogenesis by polychlorinated biphenyls.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126514

27 November 2018

The Ah receptor: a regulator of the biochemical and toxicological actions of structurally diverse chemicals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126514

27 November 2018

Orphan nuclear receptors--new ligands and new possibilities.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126514

27 November 2018

Two-stage glucocorticoid induction of CYP3A23 through both the glucocorticoid and pregnane X receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/21851831

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Halogenated biphenyls: molecular toxicology

1 reference

https://pubmed.ncbi.nlm.nih.gov/21851831

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synergistic interactions of 2,3,7,8-TCDD and 2,2',4,4',5,5'-hexachlorobiphenyl in C57BL/6J and DBA/2J mice: role of the Ah receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/21851831

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tissue-specific effects of 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) on the activity of phosphoenolpyruvate carboxykinase (PEPCK) in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/21851831

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High-resolution PCB analysis: synthesis and chromatographic properties of all 209 PCB congeners

1 reference

https://pubmed.ncbi.nlm.nih.gov/21851831

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of 3,3',4,4',5-pentachlorobiphenyl-induced fetal cleft palate and immunotoxicity in C57BL/6 mice by 2,2',4,4',5,5'-hexachlorobiphenyl

1 reference

https://pubmed.ncbi.nlm.nih.gov/21851831

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effects of 2,2',4,4',5,5'-hexachlorobiphenyl cotreatment on the disposition of 2,3,7,8-tetrachlorodibenzo-p-dioxin in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/21851831

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dose-response relationships for disposition and hepatic sequestration of polyhalogenated dibenzo-p-dioxins, dibenzofurans, and biphenyls following subchronic treatment in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/21851831

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interactive effects between 2,3,7,8-tetrachlorodibenzo-p-dioxin and 2,2',4,4',5,5'-hexachlorobiphenyl in female B6C3F1 mice: tissue distribution and tissue-specific enzyme induction

1 reference

https://pubmed.ncbi.nlm.nih.gov/21851831

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.TAAP.2011.08.002

0 references

release_artp4pqc6jechg4vzbsu2ntk2u

0 references

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