(Q28471941)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19924252%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

title

Acadesine kills chronic myelogenous leukemia (CML) cells through PKC-dependent induction of autophagic cell death (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19924252%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

0 references

1 reference

1 reference

1

1 reference

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12 February 2020

Alexandre Puissant

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19924252%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Paul Hofman

7

1 reference

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12 February 2020

Frédéric Bost

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19924252%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Patrick Auberger

10

1 reference

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12 February 2020

author name string

Issam Ben Sahra

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19924252%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Pascal Colosetti

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19924252%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Nathalie Belhacene

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19924252%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Pierre Gounon

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19924252%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Jill-Patrice Cassuto

9

1 reference

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12 February 2020

language of work or name

English

0 references

publication date

18 November 2009

1 reference

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12 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19924252%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

volume

4

1 reference

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12 February 2020

issue

11

1 reference

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12 February 2020

page(s)

e7889

1 reference

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Creative Commons Attribution 4.0 International

12 February 2020

copyright license

start time

18 November 2009

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Philadelphia chromosomal breakpoints are clustered within a limited region, bcr, on chromosome 22

19 March 2017

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Protein kinase C-dependent inhibition of the lysosomal degradation of endocytosed proteins in rat hepatocytes

19 March 2017

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AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism

7 April 2017

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Autophagy is an important event for megakaryocytic differentiation of the chronic myelogenous leukemia K562 cell line

7 April 2017

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Targeting autophagy potentiates tyrosine kinase inhibitor-induced cell death in Philadelphia chromosome-positive cells, including primary CML stem cells

29 September 2017

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Cathepsins: key modulators of cell death and inflammatory responses

29 September 2017

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To die or not to die: that is the autophagic question

29 September 2017

1 reference

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Imatinib mesylate-resistant human chronic myelogenous leukemia cell lines exhibit high sensitivity to the phytoalexin resveratrol

29 September 2017

1 reference

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The antidiabetic drug metformin exerts an antitumoral effect in vitro and in vivo through a decrease of cyclin D1 level.

29 September 2017

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Cytotoxic effect of 5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside (AICAR) on childhood acute lymphoblastic leukemia (ALL) cells: implication for targeted therapy

29 September 2017

1 reference

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Leukemia stem cells in a genetically defined murine model of blast-crisis CML.

29 September 2017

1 reference

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5-Aminoimidazole-4-carboxamide riboside sensitizes TRAIL- and TNF{alpha}-induced cytotoxicity in colon cancer cells through AMP-activated protein kinase signaling.

29 September 2017

1 reference

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Apoptosis and erythroid differentiation triggered by Bcr-Abl inhibitors in CML cell lines are fully distinguishable processes that exhibit different sensitivity to caspase inhibition.

29 September 2017

1 reference

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AMP-activated protein kinase signaling in metabolic regulation

29 September 2017

1 reference

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AMPK and cell proliferation--AMPK as a therapeutic target for atherosclerosis and cancer

29 September 2017

1 reference

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A survey of the signaling pathways involved in megakaryocytic differentiation of the human K562 leukemia cell line by molecular and c-DNA array analysis.

29 September 2017

1 reference

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5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside inhibits cancer cell proliferation in vitro and in vivo via AMP-activated protein kinase

29 September 2017

1 reference

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Cell death independent of caspases: a review.

29 September 2017

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Mimicry of a cellular low energy status blocks tumor cell anabolism and suppresses the malignant phenotype

29 September 2017

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Cleavage of Mcl-1 by caspases impaired its ability to counteract Bim-induced apoptosis.

29 September 2017

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JAK/STAT, Raf/MEK/ERK, PI3K/Akt and BCR-ABL in cell cycle progression and leukemogenesis

29 September 2017

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Imatinib induces mitochondria-dependent apoptosis of the Bcr-Abl-positive K562 cell line and its differentiation toward the erythroid lineage.

29 September 2017

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The molecular mechanism of chronic myelogenous leukemia and its therapeutic implications: studies in a murine model

29 September 2017

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29 September 2017

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The autophagosomal-lysosomal compartment in programmed cell death

29 September 2017

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Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome

29 September 2017

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29 September 2017

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29 September 2017

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RETRACTED: Selective inhibition of the platelet-derived growth factor signal transduction pathway by a protein-tyrosine kinase inhibitor of the 2-phenylaminopyrimidine class

29 September 2017

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Inducible chronic phase of myeloid leukemia with expansion of hematopoietic stem cells in a transgenic model of BCR-ABL leukemogenesis.

29 September 2017

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The protective effect of phorbol esters on Fas-mediated apoptosis in T cells. Transcriptional and postranscriptional regulation.

21 January 2018

1 reference

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Acadesine induces apoptosis in B cells from mantle cell lymphoma and splenic marginal zone lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0007889

Ischemic preconditioning activates AMPK in a PKC-dependent manner and induces GLUT4 up-regulation in the late phase of cardioprotection

21 January 2018

1 reference

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Involvement of AMPK signaling cascade in capsaicin-induced apoptosis of HT-29 colon cancer cells.

21 January 2018

1 reference

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Acadesine activates AMPK and induces apoptosis in B-cell chronic lymphocytic leukemia cells but not in T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0007889

5-Aminoimidazole-4-Carboxamide-1- -D-Ribofuranoside and Metformin Inhibit Hepatic Glucose Phosphorylation by an AMP-Activated Protein Kinase-Independent Effect on Glucokinase Translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0007889

Endopeptidase 24.11 (CD10/NEP) is required for phorbol ester-induced growth arrest in Jurkat T cells

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2775681

Inhibition of hepatic phosphatidylcholine synthesis by 5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside is independent of AMP-activated protein kinase activation

27 November 2018

1 reference

12 December 2020

Inhibition of lipopolysaccharide-induced inducible nitric oxide synthase and cyclooxygenase-2 gene expression by 5-aminoimidazole-4-carboxamide riboside is independent of AMP-activated protein kinase

1 reference

12 December 2020

Acadesine: AICA riboside, ARA 100, arasine, GP 1 110

1 reference

12 December 2020

CGP57148B (STI-571) induces differentiation and apoptosis and sensitizes Bcr-Abl-positive human leukemia cells to apoptosis due to antileukemic drugs

1 reference

12 December 2020

Diffusion-limited translocation mechanism of protein kinase C isotypes

1 reference

12 December 2020

Selective induction of apoptosis in Philadelphia chromosome-positive chronic myelogenous leukemia cells by an inhibitor of BCR–ABL tyrosine kinase, CGP 57148

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0007889

Identifiers

DOI

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19924252%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

ADS bibcode

2009PLoSO...4.7889R

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19924252%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

2 references