(Q28473625)

1

0 references

Anja Klemm

2

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Jessica Meinhardt

3

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Ulrich H Schröder

4

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Marcus Fändrich

5

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Klaus G Reymann

Creative Commons Attribution 4.0 International

6

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language of work or name

English

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publication date

18 September 2008

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published in

PLOS One

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volume

3

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issue

9

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page(s)

e3236

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copyright license

start time

18 September 2008

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

Common mechanisms of amyloid oligomer pathogenesis in degenerative disease

1 reference

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Globular amyloid beta-peptide oligomer - a homogenous and stable neuropathological protein in Alzheimer's disease

19 March 2017

1 reference

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Aging renders the brain vulnerable to amyloid beta-protein neurotoxicity

19 March 2017

1 reference

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Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptides

19 March 2017

1 reference

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Natural oligomers of the Alzheimer amyloid-beta protein induce reversible synapse loss by modulating an NMDA-type glutamate receptor-dependent signaling pathway

19 March 2017

1 reference

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Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis

19 March 2017

1 reference

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Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529401

A beta oligomers - a decade of discovery

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529401

Natural oligomers of the amyloid-beta protein specifically disrupt cognitive function

7 April 2017

1 reference

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Why Alzheimer's is a disease of memory: the attack on synapses by A beta oligomers (ADDLs).

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529401

Alzheimer's Abeta peptides containing an isostructural backbone mutation afford distinct aggregate morphologies but analogous cytotoxicity. Evidence for a common low-abundance toxic structure(s)?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529401

Directed selection of a conformational antibody domain that prevents mature amyloid fibril formation by stabilizing Abeta protofibrils

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529401

Synaptic memory mechanisms: Alzheimer's disease amyloid beta-peptide-induced dysfunction

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529401

On the structural definition of amyloid fibrils and other polypeptide aggregates

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529401

Impairments of hippocampal synaptic plasticity induced by aggregated beta-amyloid (25-35) are dependent on stimulation-protocol and genetic background.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529401

The late maintenance of hippocampal LTP: requirements, phases, 'synaptic tagging', 'late-associativity' and implications

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529401

Endomorphin-2, an endogenous tetrapeptide, protects against Abeta1-42 in vitro and in vivo

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529401

Microglia provide neuroprotection after ischemia

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529401

PGH2-derived levuglandin adducts increase the neurotoxicity of amyloid beta1-42

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529401

Early phase of amyloid beta42-induced cytotoxicity in neuronal cells is associated with vacuole formation and enhancement of exocytosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529401

The role of cell-derived oligomers of Abeta in Alzheimer's disease and avenues for therapeutic intervention.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529401

Organotypic hippocampal slice cultures for studies of brain damage, neuroprotection and neurorepair

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529401

Organotypic cultures as tools for functional screening in the CNS.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529401

Lipid homeostasis and apolipoprotein E in the development and progression of Alzheimer's disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529401

Appraisal of the MTT-based assay as a useful tool for predicting drug chemosensitivity in leukemia

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529401

Amyloid-beta oligomers: their production, toxicity and therapeutic inhibition

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529401

Understanding the biological activity of amyloid proteins in vitro: from inhibited cellular MTT reduction to altered cellular cholesterol homeostatis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529401

Microinjection of synthetic amyloid beta-protein in monkey cerebral cortex fails to produce acute neurotoxicity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529401

Inhibition of PC12 cell redox activity is a specific, early indicator of the mechanism of beta-amyloid-mediated cell death

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529401

Role of osmotic forces in exocytosis: studies of ADH-induced fusion in toad urinary bladder

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529401

The ATP-regulated K+-channel inhibitor HMR-1372 affects synaptic plasticity in hippocampal slices

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529401

Amyloid beta protein inhibits cellular MTT reduction not by suppression of mitochondrial succinate dehydrogenase but by acceleration of MTT formazan exocytosis in cultured rat cortical astrocytes.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529401

Cytotoxic amyloid peptides inhibit cellular 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) reduction by enhancing MTT formazan exocytosis.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529401

Congo red reverses amyloid beta protein-induced cellular stress in astrocytes.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529401

Mitochondrial energy metabolism is markedly impaired by D-2-hydroxyglutaric acid in rat tissues.

2 June 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0003236

Morphological and functional changes in rat hippocampal slice cultures after short-term oxygen-glucose deprivation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0003236

Protective effect of Rosa laevigata against amyloid beta peptide-induced oxidative stress.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0003236

Amyloid beta-protein potentiates tunicamycin-induced neuronal death in organotypic hippocampal slice cultures.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0003236

Different effects of monocarboxylates on neuronal survival and beta-amyloid toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0003236

Glial fibrillary acidic protein is necessary for mature astrocytes to react to beta-amyloid.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0003236

Metabolic activity of cultured rat brainstem, hippocampal and spinal cord slices.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0003236

Soluble beta-amyloid[25-35] reversibly impairs hippocampal synaptic plasticity and spatial learning.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0003236

Temperature and PMA affect different phases of exocytosis in bovine chromaffin cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0003236

Modelling of amyloid beta-peptide induced lesions using roller-drum incubation of hippocampal slice cultures from neonatal rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0003236

A three amino acid peptide, Gly-Pro-Arg, protects and rescues cell death induced by amyloid beta-peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0003236

Differential regulation by beta-amyloid peptides of intracellular free Ca2+ concentration in cultured rat microglia

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0003236

Neuroprotective effects of extracellular glutamate are absent in hippocampal organotypic cultures treated with the amyloid peptide Abeta(25-35).

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0003236

Neurotoxicity induced by amyloid beta-peptide and ibotenic acid in organotypic hippocampal cultures: protection by S-allyl-L-cysteine, a garlic compound

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0003236

ERK1/2 activation mediates Abeta oligomer-induced neurotoxicity via caspase-3 activation and tau cleavage in rat organotypic hippocampal slice cultures.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0003236

Role of caspase-12 in amyloid beta-peptide-induced toxicity in organotypic hippocampal slices cultured for long periods.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0003236

Nucleation-dependent polymerization is an essential component of amyloid-mediated neuronal cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0003236

Preparation of a tissue-like cortical primary culture from embryonic rats using Matrigel and serum free Start V Medium.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0003236

Mutagenic analysis of the nucleation propensity of oxidized Alzheimer's beta-amyloid peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0003236

Inhibition of different pathways influencing Na(+) homeostasis protects organotypic hippocampal slice cultures from hypoxic/hypoglycemic injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0003236

Influence of EGF/bFGF treatment on proliferation, early neurogenesis and infarct volume after transient focal ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0003236

Membrane-bound β-amyloid oligomers are recruited into lipid rafts by a fyn-dependent mechanism

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529401

Insulin rescues amyloid beta-induced impairment of hippocampal long-term potentiation.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529401

Suppression of Mitochondrial Succinate Dehydrogenase, a Primary Target of β‐Amyloid, and Its Derivative Racemized at Ser Residue

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529401

Nanomolar amyloid beta protein-induced inhibition of cellular redox activity in cultured astrocytes

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18800168

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Studies on succinate dehydrogenase. 13. Reversible activation of the mammalian enzyme

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18800168

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Amyloid beta-protein fibrillogenesis. Structure and biological activity of protofibrillar intermediates

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18800168