(Q35107387)

6 August 2017

title

PGH2-derived levuglandin adducts increase the neurotoxicity of amyloid beta1-42 (English)

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6 August 2017

1 reference

1 reference

5

John A Oates

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6 August 2017

1

Olivier Boutaud

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6 August 2017

4

William L Klein

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6 August 2017

2

Thomas J Montine

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6 August 2017

Lei Chang

3

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6 August 2017

language of work or name

English

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publication date

12 January 2006

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Journal of Neurochemistry

6 August 2017

published in

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6 August 2017

volume

96

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6 August 2017

issue

4

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6 August 2017

page(s)

917-923

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Prostaglandin H(2)-derived adducts of proteins correlate with Alzheimer's disease severity

6 August 2017

cites work

1 reference

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9 July 2018

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Synaptic targeting by Alzheimer's-related amyloid beta oligomers.

9 July 2018

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Metabolite-initiated protein misfolding may trigger Alzheimer's disease

9 July 2018

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Advanced glycation endproduct precursor alters intracellular amyloid-beta/A beta PP carboxy-terminal fragment aggregation and cytotoxicity

9 July 2018

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Copper, beta-amyloid, and Alzheimer's disease: tapping a sensitive connection

9 July 2018

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Femtomole Immunodetection of Synthetic and Endogenous Amyloid-β Oligomers and Its Application to Alzheimer's Disease Drug Candidate Screening

9 July 2018

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Alzheimer's disease-affected brain: presence of oligomeric A beta ligands (ADDLs) suggests a molecular basis for reversible memory loss

9 July 2018

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Trace amounts of copper in water induce beta-amyloid plaques and learning deficits in a rabbit model of Alzheimer's disease

9 July 2018

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NSAIDs and enantiomers of flurbiprofen target gamma-secretase and lower Abeta 42 in vivo

9 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1621054

Evidence that nonsteroidal anti-inflammatory drugs decrease amyloid beta 42 production by direct modulation of gamma-secretase activity

9 July 2018

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In vitro characterization of conditions for amyloid-beta peptide oligomerization and fibrillogenesis

9 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1621054

Prostaglandin H2 (PGH2) accelerates formation of amyloid beta1-42 oligomers

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1621054

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

9 July 2018

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Determinants of the cellular specificity of acetaminophen as an inhibitor of prostaglandin H(2) synthases.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1621054

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1621054

Characterization of the lysyl adducts of prostaglandin H-synthases that are derived from oxygenation of arachidonic acid

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1621054

Ibuprofen suppresses plaque pathology and inflammation in a mouse model for Alzheimer's disease.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1621054

Characterization of the lysyl adducts formed from prostaglandin H2 via the levuglandin pathway

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1621054

Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1621054

Risk of Alzheimer's disease and duration of NSAID use.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1621054

Water-soluble Abeta (N-40, N-42) oligomers in normal and Alzheimer disease brains.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1621054

Inhibition of PC12 cell redox activity is a specific, early indicator of the mechanism of beta-amyloid-mediated cell death

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1621054

The intracellular component of cellular 3-(4,5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide (MTT) reduction is specifically inhibited by beta-amyloid peptides.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1621054

Levuglandinyl adducts of proteins are formed via a prostaglandin H2 synthase-dependent pathway after platelet activation

9 July 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03586.X

Modification of proteins by isoketal-containing oxidized phospholipids

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03586.X

Oligomeric and fibrillar species of amyloid-beta peptides differentially affect neuronal viability.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03586.X

A seed for Alzheimer amyloid in the brain.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03586.X

Inhibition of toxicity in the beta-amyloid peptide fragment beta -(25-35) using N-methylated derivatives: a general strategy to prevent amyloid formation.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03586.X

Vaccination with soluble Abeta oligomers generates toxicity-neutralizing antibodies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03586.X

Inflammatory molecule release by beta-amyloid-treated T98G astrocytoma cells: role of prostaglandins and modulation by paracetamol.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03586.X

Ibuprofen effects on Alzheimer pathology and open field activity in APPsw transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03586.X

Prostaglandins as putative neurotoxins in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03586.X

Morphology and toxicity of Abeta-(1-42) dimer derived from neuritic and vascular amyloid deposits of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03586.X

Prostaglandin endoperoxides. 14. Solvent-induced fragmentation of prostaglandin endoperoxides. New aldehyde products from PGH2 and a novel intramolecular 1,2-hydride shift during endoperoxide fragmentation in aqueous solution

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03586.X

A subset of NSAIDs lower amyloidogenic Abeta42 independently of cyclooxygenase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03586.X

Cyclooxygenase-2 promotes amyloid plaque deposition in a mouse model of Alzheimer's disease neuropathology.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1621054

Age-dependent cognitive deficits and neuronal apoptosis in cyclooxygenase-2 transgenic mice.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1621054

Copper catalyzed oxidation of Alzheimer Abeta.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1621054

Protofibrillar intermediates of amyloid beta-protein induce acute electrophysiological changes and progressive neurotoxicity in cortical neurons.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1621054

Nonsteroidal Antiinflammatory Drugs and the Risk of Alzheimer's Disease

27 September 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03586.X

Levuglandin E2 crosslinks proteins

21 January 2018

1 reference

12 December 2020

Secondary structure of amyloid beta peptide correlates with neurotoxic activity in vitro

1 reference

12 December 2020

The mechanism of nucleophilic substitution of alkylpyrroles in the presence of oxygen

1 reference

12 December 2020

Reactions of 4-hydroxy-2(E)-nonenal and related aldehydes with proteins studied by carbon-13 nuclear magnetic resonance spectroscopy

1 reference

12 December 2020

Identification of extremely reactive gamma-ketoaldehydes (isolevuglandins) as products of the isoprostane pathway and characterization of their lysyl protein adducts

1 reference

12 December 2020

Elevated CSF prostaglandin E2 levels in patients with probable AD

1 reference

12 December 2020

10.1111/J.1471-4159.2005.03586.X

Identifiers

DOI

1 reference

6 August 2017

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6 August 2017

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