(Q28475611)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19536284%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

title

Prion protein paralog doppel protein interacts with alpha-2-macroglobulin: a plausible mechanism for doppel-mediated neurodegeneration (English)

1 reference

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31 January 2020

0 references

1 reference

1

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31 January 2020

Angela Bachi

4

1 reference

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31 January 2020

Paola Torreri

6

1 reference

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31 January 2020

Giuseppe Legname

9

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31 January 2020

author name string

Diego Franciotta

2

1 reference

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31 January 2020

Josh Sussman

3

1 reference

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31 January 2020

Elisabetta Zardini

5

1 reference

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31 January 2020

Cedric Govaerts

7

1 reference

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31 January 2020

Salvatore Pizzo

8

1 reference

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31 January 2020

language of work or name

English

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publication date

18 June 2009

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31 January 2020

1 reference

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31 January 2020

volume

4

1 reference

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31 January 2020

issue

6

1 reference

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31 January 2020

page(s)

e5968

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Creative Commons Attribution 4.0 International

31 January 2020

copyright license

start time

18 June 2009

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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19 March 2017

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Two different neurodegenerative diseases caused by proteins with similar structures

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19 March 2017

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Ataxia in prion protein (PrP)-deficient mice is associated with upregulation of the novel PrP-like protein doppel

19 March 2017

1 reference

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Gapped BLAST and PSI-BLAST: a new generation of protein database search programs

19 March 2017

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19 March 2017

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Mass Spectrometric Sequencing of Proteins from Silver-Stained Polyacrylamide Gels

19 March 2017

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CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

19 March 2017

1 reference

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The alpha-macroglobulin bait region. Sequence diversity and localization of cleavage sites for proteinases in five mammalian alpha-macroglobulins

19 March 2017

1 reference

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The prion protein family: diversity, rivalry, and dysfunction

19 March 2017

1 reference

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Prions and their partners in crime

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2693666

Male infertility and DNA damage in Doppel knockout and prion protein/Doppel double-knockout mice

29 September 2017

1 reference

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Physiological and pathological functions of the prion protein homologue Dpl

29 September 2017

1 reference

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Cooperative binding of dominant-negative prion protein to kringle domains

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2693666

Prion and doppel proteins bind to granule cells of the cerebellum

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2693666

Absence of the prion protein homologue Doppel causes male sterility

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2693666

Cellular prion protein transduces neuroprotective signals

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2693666

Onset of ataxia and Purkinje cell loss in PrP null mice inversely correlated with Dpl level in brain

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2693666

Doppel is an N-glycosylated, glycosylphosphatidylinositol-anchored protein. Expression in testis and ectopic production in the brains of Prnp(0/0) mice predisposed to Purkinje cell loss

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2693666

Role of the low-density lipoprotein receptor-related protein in beta-amyloid metabolism and Alzheimer disease

29 September 2017

1 reference

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alpha 2-Macroglobulin, complement, and biologic defense: antigens, growth factors, microbial proteases, and receptor ligation

29 September 2017

1 reference

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Clearance and binding of two electrophoretic "fast" forms of human alpha 2-macroglobulin.

29 September 2017

1 reference

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A conserved region in alpha-macroglobulins participates in binding to the mammalian alpha-macroglobulin receptor

29 September 2017

1 reference

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Direct tissue isoelectric focusing in agarose.

29 September 2017

1 reference

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Blood-testis barrier dynamics are regulated by {alpha}2-macroglobulin via the c-Jun N-terminal protein kinase pathway

29 September 2017

1 reference

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Physiological expression of the gene for PrP-like protein, PrPLP/Dpl, by brain endothelial cells and its ectopic expression in neurons of PrP-deficient mice ataxic due to Purkinje cell degeneration

2 June 2018

1 reference

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Expression of amino-terminally truncated PrP in the mouse leading to ataxia and specific cerebellar lesions

2 June 2018

1 reference

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Alpha2-macroglobulin complexes with and mediates the endocytosis of beta-amyloid peptide via cell surface low-density lipoprotein receptor-related protein.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2693666

Multiple, diverse senile plaque-associated proteins are ligands of an apolipoprotein E receptor, the alpha 2-macroglobulin receptor/low-density-lipoprotein receptor-related protein.

2 June 2018

1 reference

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Biosynthesis and regulation of rat alpha 1-inhibitor3, a negative acute-phase reactant of the macroglobulin family

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2693666

Rapid detection of Creutzfeldt-Jakob disease and scrapie prion proteins

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2693666

Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2693666

Detection of interleukin-6 and alpha 2-macroglobulin immunoreactivity in cortex and hippocampus of Alzheimer's disease patients

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2693666

Alpha2-macroglobulin is a potential facilitator of prion protein transformation.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2693666

The low-density lipoprotein receptor-related protein 1 (LRP1) mediates the endocytosis of the cellular prion protein

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2693666

Interaction of cellular prion and stress-inducible protein 1 promotes neuritogenesis and neuroprotection by distinct signaling pathways.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2693666

Welcome to the complex disease world. Alpha2-macroglobulin and Alzheimer's disease.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2693666

A human prion protein peptide (PrP59–91) protects against copper neurotoxicity

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2693666

Deletion of N-terminal residues 23-88 from prion protein (PrP) abrogates the potential to rescue PrP-deficient mice from PrP-like protein/doppel-induced Neurodegeneration

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2693666

Antibodies inhibit prion propagation and clear cell cultures of prion infectivity

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2693666

Alpha2 macroglobulin and the risk of Alzheimer's disease.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2693666

Genetic association of an alpha2-macroglobulin (Val1000lle) polymorphism and Alzheimer's disease.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2693666

Alpha-2 macroglobulin is genetically associated with Alzheimer disease

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2693666

Mice with gene targetted prion protein alterations show that Prnp, Sinc and Prni are congruent

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2693666

Loss of cerebellar Purkinje cells in aged mice homozygous for a disrupted PrP gene.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2693666

129/Ola mice carrying a null mutation in PrP that abolishes mRNA production are developmentally normal

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2693666

Alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein. Relationship to apolipoprotein E and role in Alzheimer disease senile plaques.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2693666

A sensitive silver stain for proteins in agarose gels.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2693666

LRP1 controls biosynthetic and endocytic trafficking of neuronal prion protein

27 November 2018

1 reference

12 December 2020

A rapid method for detecting oligoclonal IgG in unconcentrated CSF, by agarose isoelectric focusing, transfer to cellulose nitrate and immunoperoxidase staining

1 reference

12 December 2020

The immunohistochemical localization of alpha 2-macroglobulin in rat testes is consistent with its role in germ cell movement and spermiation

1 reference

12 December 2020

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0005968

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19536284%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19536284%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

PubMed publication ID

19536284

1 reference