(Q36628157)

15 August 2017

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title

Prions and their partners in crime (English)

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15 August 2017

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1

Byron Caughey

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15 August 2017

Gerald S Baron

2

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15 August 2017

language of work or name

English

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publication date

1 October 2006

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15 August 2017

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15 August 2017

volume

443

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15 August 2017

issue

7113

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15 August 2017

page(s)

803-810

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https://scigraph.springernature.com/pub.10.1038/nature05294

15 August 2017

exact match

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cites work

Protease-resistant prion protein produced in vitro lacks detectable infectivity.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

Synthetic mammalian prions

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

Strain-specified characteristics of mouse synthetic prions

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

Serial transmission in rodents of neurodegeneration from transgenic mice expressing mutant prion protein

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

Immunodetection of disease-associated mutant PrP, which accelerates disease in GSS transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

In vitro generation of infectious scrapie prions.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

Protease-resistant prion protein amplification reconstituted with partially purified substrates and synthetic polyanions.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

Sulfated glycans and elevated temperature stimulate PrP(Sc)-dependent cell-free formation of protease-resistant prion protein

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

Heparan sulfate is a cellular receptor for purified infectious prions.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

PrPSc incorporation to cells requires endogenous glycosaminoglycan expression

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

Cellular heparan sulfate participates in the metabolism of prions

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

Reconstitution of prion infectivity from solubilized protease-resistant PrP and nonprotein components of prion rods

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

A 'unified theory' of prion propagation

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

The hypothesis of the catalytic action of nucleic acid on the conversion of prion protein

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

The 37 kDa/67 kDa laminin receptor is required for PrP(Sc) propagation in scrapie-infected neuronal cells

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

The most infectious prion protein particles.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

Protofibrils, pores, fibrils, and neurodegeneration: separating the responsible protein aggregates from the innocent bystanders

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

Anchorless prion protein results in infectious amyloid disease without clinical scrapie

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

Normal host prion protein necessary for scrapie-induced neurotoxicity.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

Depleting neuronal PrP in prion infection prevents disease and reverses spongiosis.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

The disulfide isomerase Grp58 is a protective factor against prion neurotoxicity.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

Astrocyte-specific expression of hamster prion protein (PrP) renders PrP knockout mice susceptible to hamster scrapie

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

Scrapie-specific neuronal lesions are independent of neuronal PrP expression

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

Pathological prion protein exposure switches on neuronal mitogen-activated protein kinase pathway resulting in microglia recruitment

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

New insights into prion structure and toxicity.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

Is loss of function of the prion protein the cause of prion disorders?

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

Rational targeting for prion therapeutics.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

Prion diseases: what is the neurotoxic molecule?

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

Cellular prion protein neuroprotective function: implications in prion diseases

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

Cellular prion protein: on the road for functions

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

The prion protein and neuronal zinc homeostasis

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

Cellular prion protein function in copper homeostasis and redox signalling at the synapse

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

Prion protein recruits its neuronal receptor NCAM to lipid rafts to activate p59fyn and to enhance neurite outgrowth.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

Interaction of cellular prion and stress-inducible protein 1 promotes neuritogenesis and neuroprotection by distinct signaling pathways.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

Axonal transport of the cellular prion protein is increased during axon regeneration.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

Recombinant prion protein induces rapid polarization and development of synapses in embryonic rat hippocampal neurons in vitro

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

Altered circadian activity rhythms and sleep in mice devoid of prion protein

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

Prion protein is necessary for normal synaptic function

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

Mice devoid of prion protein have cognitive deficits that are rescued by reconstitution of PrP in neurons

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

The cellular prion protein binds copper in vivo

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

Overexpression of PrPC by adenovirus-mediated gene targeting reduces ischemic injury in a stroke rat model.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

The cellular prion protein modulates phagocytosis and inflammatory response

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

Prion protein is expressed on long-term repopulating hematopoietic stem cells and is important for their self-renewal

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

Prion protein (PrPc) positively regulates neural precursor proliferation during developmental and adult mammalian neurogenesis

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

Altered behavioural response to acute stress in mice lacking cellular prion protein

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

Mice deficient for prion protein exhibit normal neuronal excitability and synaptic transmission in the hippocampus

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

Brain copper content and cuproenzyme activity do not vary with prion protein expression level

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

Role of microglia and host prion protein in neurotoxicity of a prion protein fragment.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

Neurotoxicity of prion peptide 106-126 not confirmed

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

Neurotoxicity and neurodegeneration when PrP accumulates in the cytosol

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

Mutant PrP is delayed in its exit from the endoplasmic reticulum, but neither wild-type nor mutant PrP undergoes retrotranslocation prior to proteasomal degradation

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

Cellular prion protein promotes Brucella infection into macrophages

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

Absence of evidence for the participation of the macrophage cellular prion protein in infection with Brucella suis

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

Prion Protein Interaction with Glycosaminoglycan Occurs with the Formation of Oligomeric Complexes Stabilized by Cu(II) Bridges

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

Potent antiscrapie activities of degenerate phosphorothioate oligonucleotides

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

A trans-dominant negative 37kDa/67kDa laminin receptor mutant impairs PrP(Sc) propagation in scrapie-infected neuronal cells.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

Bovine prion is endocytosed by human enterocytes via the 37 kDa/67 kDa laminin receptor.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

Identification of interaction domains of the prion protein with its 37-kDa/67-kDa laminin receptor

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

Knock-down of the 37-kDa/67-kDa laminin receptor in mouse brain by transgenic expression of specific antisense LRP RNA.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

Cellular prion protein acquires resistance to proteolytic degradation following copper ion binding

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

Copper converts the cellular prion protein into a protease-resistant species that is distinct from the scrapie isoform

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

Copper binding to PrPC may inhibit prion disease propagation

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

Misfolding of the prion protein at the plasma membrane induces endocytosis, intracellular retention and degradation

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

Copper chelation delays the onset of prion disease

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

Reversibility of scrapie inactivation is enhanced by copper.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

Ionic strength and transition metals control PrPSc protease resistance and conversion-inducing activity.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

Copper (II) ions potently inhibit purified PrPres amplification

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

Copper(II) inhibits in vitro conversion of prion protein into amyloid fibrils.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

Uptake and neuritic transport of scrapie prion protein coincident with infection of neuronal cells.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

Conversion of raft associated prion protein to the protease-resistant state requires insertion of PrP-res (PrP(Sc)) into contiguous membranes

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

Cellular prion protein binds laminin and mediates neuritogenesis

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

Prion protein as trans-interacting partner for neurons is involved in neurite outgrowth and neuronal survival

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

Cross-Linking Cellular Prion Protein Triggers Neuronal Apoptosis in Vivo

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

Assigning functions to distinct regions of the N-terminus of the prion protein that are involved in its copper-stimulated, clathrin-dependent endocytosis

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

NADPH oxidase and extracellular regulated kinases 1/2 are targets of prion protein signaling in neuronal and nonneuronal cells.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

Cellular isoform of the scrapie agent protein participates in lymphocyte activation

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

Overexpression of cellular prion protein induces an antioxidant environment altering T cell development in the thymus

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

The highways and byways of prion protein trafficking

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

N-terminal truncation of the scrapie-associated form of PrP by lysosomal protease(s): implications regarding the site of conversion of PrP to the protease-resistant state

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

S-nitrosylated protein-disulphide isomerase links protein misfolding to neurodegeneration

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

Cells release prions in association with exosomes

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

A porphyrin increases survival time of mice after intracerebral prion infection

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

Inhibition of protease-resistant prion protein formation in a transformed deer cell line infected with chronic wasting disease

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

Prion diseases--close to effective therapy?

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

Treatment of transmissible spongiform encephalopathy by intraventricular drug infusion in animal models

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

Prions and transmissible spongiform encephalopathy (TSE) chemotherapeutics: A common mechanism for anti-TSE compounds?

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

Identification of the heparan sulfate binding sites in the cellular prion protein

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

The N-terminal domain of a glycolipid-anchored prion protein is essential for its endocytosis via clathrin-coated pits

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

Prion proteins with insertion mutations have altered N-terminal conformation and increased ligand binding activity and are more susceptible to oxidative attack

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05294

7 January 2021

Identifiers

DOI

10.1038/NATURE05294

1 reference

release_vuqljpi4e5f2xep5mqomlhnsuq

15 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/vuqljpi4e5f2xep5mqomlhnsuq

24 November 2022

mapped directly with Wikidata item

1 reference