(Q28476371)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21829464%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

title

Pancreatic β-cell death in response to pro-inflammatory cytokines is distinct from genuine apoptosis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21829464%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

0 references

1 reference

7

1 reference

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10 February 2020

author name string

J Jason Collier

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21829464%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

Susan J Burke

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21829464%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

Mary E Eisenhauer

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21829464%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

Danhong Lu

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21829464%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

Renee C Sapp

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21829464%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

Carlie J Frydman

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21829464%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

language of work or name

English

0 references

publication date

29 July 2011

1 reference

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10 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21829464%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

volume

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21829464%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

issue

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21829464%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

page(s)

e22485

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21829464%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

10 February 2020

copyright license

start time

29 July 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Release of chromatin protein HMGB1 by necrotic cells triggers inflammation

19 March 2017

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Nitric oxide suppresses apoptosis via interrupting caspase activation and mitochondrial dysfunction in cultured hepatocytes

19 March 2017

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Stable expression of manganese superoxide dismutase (MnSOD) in insulinoma cells prevents IL-1beta- induced cytotoxicity and reduces nitric oxide production

19 March 2017

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Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

19 March 2017

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19 March 2017

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Nitric oxide mediates cytokine-induced inhibition of insulin secretion by human islets of Langerhans

19 March 2017

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Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

19 March 2017

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Does nitric oxide mediate autoimmune destruction of beta-cells? Possible therapeutic interventions in IDDM

19 March 2017

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Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis

19 March 2017

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p53 up-regulated modulator of apoptosis (PUMA) activation contributes to pancreatic beta-cell apoptosis induced by proinflammatory cytokines and endoplasmic reticulum stress

19 March 2017

1 reference

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c-Myc is required for the glucose-mediated induction of metabolic enzyme genes

19 March 2017

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Shared principles in NF-kappaB signaling

19 March 2017

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Java Treeview--extensible visualization of microarray data

7 April 2017

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Missing pieces in the NF-kappaB puzzle

7 April 2017

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RIP3 mediates the embryonic lethality of caspase-8-deficient mice

7 April 2017

1 reference

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Apoptosis: controlled demolition at the cellular level

7 April 2017

1 reference

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NF-kappaB: a key role in inflammatory diseases

7 April 2017

1 reference

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Establishment of 2-mercaptoethanol-dependent differentiated insulin-secreting cell lines

7 April 2017

1 reference

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Functional complementation between FADD and RIP1 in embryos and lymphocytes

7 April 2017

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Bioenergetics and cell death.

29 September 2017

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Autophagy facilitates IFN-gamma-induced Jak2-STAT1 activation and cellular inflammation

29 September 2017

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The molecular regulation of programmed necrotic cell injury

29 September 2017

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Regulation of NF-kappaB activity through lysine monomethylation of p65.

29 September 2017

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Nitric oxides mediates a shift from early necrosis to late apoptosis in cytokine-treated β-cells that is associated with irreversible DNA damage.

29 September 2017

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The role of mitochondria in apoptosis*.

29 September 2017

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Repair of nitric oxide-damaged DNA in beta-cells requires JNK-dependent GADD45alpha expression

29 September 2017

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Proinflammatory cytokines activate the intrinsic apoptotic pathway in beta-cells

29 September 2017

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Role of increased ROS dissipation in prevention of T1D.

29 September 2017

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Transfusion of apoptotic beta-cells induces immune tolerance to beta-cell antigens and prevents type 1 diabetes in NOD mice

29 September 2017

1 reference

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Pro- and antiapoptotic proteins regulate apoptosis but do not protect against cytokine-mediated cytotoxicity in rat islets and beta-cell lines

29 September 2017

1 reference

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Macrophages use different internalization mechanisms to clear apoptotic and necrotic cells

29 September 2017

1 reference

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Necrotic death as a cell fate

29 September 2017

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Intracellular signaling mechanisms in photodynamic therapy

29 September 2017

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6-Hydroxydopamine induces dopaminergic cell degeneration via a caspase-9-mediated apoptotic pathway that is attenuated by caspase-9dn expression

29 September 2017

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29 September 2017

1 reference

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Regulation of the apoptosis-necrosis switch

29 September 2017

1 reference

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Photodynamic therapy of human breast cancer xenografts lacking caspase-3.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146470

beta-Cell death during progression to diabetes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146470

Nitric oxide can inhibit apoptosis or switch it into necrosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146470

Cell injury releases endogenous adjuvants that stimulate cytotoxic T cell responses

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146470

Isolation of INS-1-derived cell lines with robust ATP-sensitive K+ channel-dependent and -independent glucose-stimulated insulin secretion

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146470

Natural adjuvants: endogenous activators of dendritic cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146470

Role of cytochrome c and dATP/ATP hydrolysis in Apaf-1-mediated caspase-9 activation and apoptosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146470

IL-1 produced and released endogenously within human islets inhibits beta cell function

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146470

The role of interleukin-1 in the pathogenesis of IDDM.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146470

Physiology and pathophysiology of nitric oxide.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146470

Apoptosis: the biochemistry and molecular biology of programmed cell death

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146470

Predicting type I diabetes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146470

Essential contribution of macrophages to islet cell destruction in vivo and in vitro

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146470

Interleukin 1 beta induces the formation of nitric oxide by beta-cells purified from rodent islets of Langerhans. Evidence for the beta-cell as a source and site of action of nitric oxide

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146470

Autophagy is important in islet homeostasis and compensatory increase of beta cell mass in response to high-fat diet

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146470

Quorum sensing controls biofilm formation in Vibrio cholerae through modulation of cyclic di-GMP levels and repression of vpsT

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146470

Free radical modulation of insulin release in INS-1 cells exposed to alloxan

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146470

A role for nitric oxide and other inflammatory mediators in cytokine-induced pancreatic beta-cell dysfunction and destruction

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146470

Irreversible inhibition of metabolic function and islet destruction after a 36-hour exposure to interleukin-1beta.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146470

Nitric oxide inhibits apoptosis by preventing increases in caspase-3-like activity via two distinct mechanisms

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146470

Dual functional effects of interleukin-1beta on purine nucleotides and insulin secretion in rat islets and INS-1 cells

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146470

Evidence that DNA topoisomerase I is necessary for the cytotoxic effects of camptothecin.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146470

Polyvinylpyrrolidone as a Blocking Agent in Immunochemical Studies

2 June 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0022485

Separation and quantitation of water soluble cellular metabolites by hydrophilic interaction chromatography-tandem mass spectrometry.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0022485

Low concentration of interleukin-1beta induces FLICE-inhibitory protein-mediated beta-cell proliferation in human pancreatic islets

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0022485

Nitric oxide donors inhibit formation of the Apaf-1/caspase-9 apoptosome and activation of caspases

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0022485

Attenuation of murine collagen-induced arthritis by a novel, potent, selective small molecule inhibitor of IkappaB Kinase 2, TPCA-1 (2-[(aminocarbonyl)amino]-5-(4-fluorophenyl)-3-thiophenecarboxamide), occurs via reduction of proinflammatory cytokin

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0022485

beta-cell apoptosis and defense mechanisms: lessons from type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0022485

Antitumor effects of photodynamic therapy are potentiated by 2-methoxyestradiol. A superoxide dismutase inhibitor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0022485

Rapamycin induces autophagy in islets: relevance in islet transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0022485

Protection of islets by in situ peptide-mediated transduction of the Ikappa B kinase inhibitor Nemo-binding domain peptide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0022485

Necrosis Is the Predominant Type of Islet Cell Death During Development of Insulin-Dependent Diabetes Mellitus in BB Rats

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146470

Inhibition of proinflammatory molecule production by adenovirus-mediated expression of a nuclear factor kappaB super-repressor in human intestinal epithelial cells

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146470

Immunosuppressive effects of apoptotic cells

27 November 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0022485

Protection of human islets from the effects of interleukin-1beta by adenoviral gene transfer of an Ikappa B repressor

21 January 2018

1 reference

12 December 2020

Inhibition of cytokine-induced NF-kappaB activation by adenovirus-mediated expression of a NF-kappaB super-repressor prevents beta-cell apoptosis

1 reference

12 December 2020

Immunolocalization of caspase-3 in pancreatic islets of NOD mice during cyclophosphamide-accelerated diabetes

1 reference

12 December 2020

Islet cytotoxicity of interleukin 1. Influence of culture conditions and islet donor characteristics

1 reference

12 December 2020

Destruction of rat islet cell monolayers by cytokines. Synergistic interactions of interferon-gamma, tumor necrosis factor, lymphotoxin, and interleukin 1

1 reference

12 December 2020

Interleukin-1 inhibits glucose-modulated insulin and glucagon secretion in rat islet monolayer cultures

1 reference

12 December 2020

Reactive oxygen intermediates in autoimmune islet cell destruction of the NOD mouse induced by peritoneal exudate cells (rich in macrophages) but not T cells

1 reference

12 December 2020

Transgenic overexpression of human Bcl-2 in islet β cells inhibits apoptosis but does not prevent autoimmune destruction

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0022485

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21829464%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21829464%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

1 reference