(Q28481391)

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Novel RNAi-mediated approach to G protein-coupled receptor deorphanization: proof of principle and characterization of a planarian 5-HT receptor

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Novel RNAi-mediated approach to G protein-coupled receptor deorphanization: proof of principle and characterization of a planarian 5-HT receptor (English)

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G protein-coupled receptor

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Mostafa Zamanian

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Mostafa Zamanian

1

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Tim A Day

6

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author name string

Prince N Agbedanu

2

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Nicolas J Wheeler

3

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Paul McVeigh

4

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Michael J Kimber

5

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2012

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7

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7

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e40787

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Creative Commons Attribution 4.0 International

18 July 2012

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April 2022 Public Data File from Crossref

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Genome-wide analyses reveal a role for peptide hormones in planarian germline development

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19 March 2017

The genome of the blood fluke Schistosoma mansoni

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19 March 2017

The Schistosoma japonicum genome reveals features of host-parasite interplay

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19 March 2017

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19 March 2017

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19 March 2017

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19 March 2017

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19 March 2017

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19 March 2017

Structural diversity of G protein-coupled receptors and significance for drug discovery

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7 April 2017

The repertoire of G protein-coupled receptors in the human parasite Schistosoma mansoni and the model organism Schmidtea mediterranea

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29 September 2017

The identification of inhibitors of Schistosoma mansoni miracidial transformation by incorporating a medium-throughput small-molecule screen

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29 September 2017

Investigation of a dopamine receptor in Schistosoma mansoni: functional studies and immunolocalization

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29 September 2017

Discovery of multiple neuropeptide families in the phylum Platyhelminthes.

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29 September 2017

Orphan GPCR research

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29 September 2017

SmedGD: the Schmidtea mediterranea genome database

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29 September 2017

Heterologous GPCR expression: a bottleneck to obtaining crystal structures

1 reference

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29 September 2017

G protein coupled receptor structure and activation

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29 September 2017

Regulation of G protein-coupled receptor export trafficking.

1 reference

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29 September 2017

Role of cholesterol in the function and organization of G-protein coupled receptors.

1 reference

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29 September 2017

Neuropeptide signalling systems in flatworms

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29 September 2017

Classical transmitters and their receptors in flatworms

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399857

29 September 2017

Functional assays for screening GPCR targets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399857

29 September 2017

The regulatory mechanisms of export trafficking of G protein-coupled receptors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399857

29 September 2017

Postgenomic characterization of G-protein-coupled receptors

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399857

29 September 2017

Forskolin as a tool for examining adenylyl cyclase expression, regulation, and G protein signaling.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399857

29 September 2017

Specific lipid requirements of membrane proteins--a putative bottleneck in heterologous expression

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399857

29 September 2017

Target validation of G-protein coupled receptors

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399857

29 September 2017

Receptor activity modifying proteins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399857

29 September 2017

Modelling G-protein-coupled receptors for drug design

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399857

29 September 2017

Phylogenetic analysis using PHYLIP.

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29 September 2017

Molecular identification of a G protein-coupled receptor family which is expressed in planarians

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399857

29 September 2017

Identification of planarian serotonin receptor by ligand binding and PCR studies.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399857

29 September 2017

Heterologous expression of G-protein-coupled receptors

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399857

29 September 2017

Adenosine 3',5'-Monophosphate, Luteinizing Hormone Receptor, and Progesterone during Granulosa Cell Differentiation: Effects of Estradiol and Follicle- Stimulating Hormone*

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29 September 2017

Beta-catenin defines head versus tail identity during planarian regeneration and homeostasis

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2 June 2018

Identification of genes needed for regeneration, stem cell function, and tissue homeostasis by systematic gene perturbation in planaria

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2 June 2018

A novel Schistosoma mansoni G protein-coupled receptor is responsive to histamine

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2 June 2018

G-protein signaling: satisfying the basic necessities of life.

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21 January 2018

Identification of a platyhelminth neuropeptide receptor

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21 January 2018

Histamine signalling in Schistosoma mansoni: immunolocalisation and characterisation of a new histamine-responsive receptor (SmGPR-2).

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21 January 2018

Identification of a novel planarian G-protein-coupled receptor that responds to serotonin in Xenopus laevis oocytes

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21 January 2018

Structure and bioactivity of neuropeptide F from the human parasites Schistosoma mansoni and Schistosoma japonicum.

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21 January 2018

Behavioral characterization of serotonergic activation in the flatworm Planaria

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0040787

21 January 2018

Whole-genome analysis of 60 G protein-coupled receptors in Caenorhabditis elegans by gene knockout with RNAi

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serotonin-activated adenylate cyclase during early development of Schistosoma mansoni

1 reference

https://pubmed.ncbi.nlm.nih.gov/22815820

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nature of serotonin-activated adenylate cyclase during development of Schistosoma mansoni

1 reference

https://pubmed.ncbi.nlm.nih.gov/22815820

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a 5-HT1A receptor positively coupled to planarian adenylate cyclase

1 reference

https://pubmed.ncbi.nlm.nih.gov/22815820

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0040787

1 reference

Consolidated OpenCitations Corpus – April 2017

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1 reference

Consolidated OpenCitations Corpus – April 2017

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PMC publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PubMed publication ID

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Consolidated OpenCitations Corpus – April 2017

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