(Q28482261)

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Human monoclonal antibodies to a novel cluster of conformational epitopes on HCV E2 with resistance to neutralization escape in a genotype 2a isolate

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Human monoclonal antibodies to a novel cluster of conformational epitopes on HCV E2 with resistance to neutralization escape in a genotype 2a isolate (English)

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1 reference

based on heuristic

inferred from title

monoclonal antibody

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based on heuristic

inferred from title

Jannick Prentoe

object named as

Jannick Prentoe

6

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object named as

Felix A Rey

12

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object named as

Jens Bukh

11

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13

object named as

Steven K H Foung

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1

object named as

Zhen-yong Keck

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3

object named as

Yong Wang

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9

object named as

Arvind H Patel

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2

object named as

Jinming Xia

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Stanley M Lemon

10

object named as

Stanley M Lemon

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author name string

Wenyan Wang

4

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Thomas Krey

5

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Thomas Carlsen

7

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Angela Ying-Jian Li

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language of work or name

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publication date

2012

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8

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4

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e1002653

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copyright license

Creative Commons Attribution 4.0 International

12 April 2012

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April 2022 Public Data File from Crossref

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The Disulfide Bonds in Glycoprotein E2 of Hepatitis C Virus Reveal the Tertiary Organization of the Molecule

1 reference

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Identification and Characterization of Broadly Neutralizing Human Monoclonal Antibodies Directed against the E2 Envelope Glycoprotein of Hepatitis C Virus

1 reference

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19 March 2017

Mutations in Hepatitis C Virus E2 Located outside the CD81 Binding Sites Lead to Escape from Broadly Neutralizing Antibodies but Compromise Virus Infectivity

1 reference

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19 March 2017

In vitro selection of a neutralization-resistant hepatitis C virus escape mutant

1 reference

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Definition of a Conserved Immunodominant Domain on Hepatitis C Virus E2 Glycoprotein by Neutralizing Human Monoclonal Antibodies

1 reference

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19 March 2017

A Point Mutation Leading to Hepatitis C Virus Escape from Neutralization by a Monoclonal Antibody to a Conserved Conformational Epitope

1 reference

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Dissecting the role of putative CD81 binding regions of E2 in mediating HCV entry: Putative CD81 binding region 1 is not involved in CD81 binding

1 reference

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Development of JFH1-based cell culture systems for hepatitis C virus genotype 4a and evidence for cross-genotype neutralization

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Identification of a Broadly Cross-Reacting and Neutralizing Human Monoclonal Antibody Directed against the Hepatitis C Virus E2 Protein

1 reference

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Human combinatorial libraries yield rare antibodies that broadly neutralize hepatitis C virus

1 reference

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19 March 2017

Expression and Characterization of a Minimal Hepatitis C Virus Glycoprotein E2 Core Domain That Retains CD81 Binding

1 reference

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Characterization of Fusion Determinants Points to the Involvement of Three Discrete Regions of Both E1 and E2 Glycoproteins in the Membrane Fusion Process of Hepatitis C Virus

1 reference

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19 March 2017

The Neutralizing Activity of Anti-Hepatitis C Virus Antibodies Is Modulated by Specific Glycans on the E2 Envelope Protein

1 reference

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19 March 2017

Hepatitis C Virus Envelope Glycoprotein E2 Glycans Modulate Entry, CD81 Binding, and Neutralization

1 reference

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Hepatitis C virus epitope-specific neutralizing antibodies in Igs prepared from human plasma

1 reference

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Rapid induction of virus-neutralizing antibodies and viral clearance in a single-source outbreak of hepatitis C

1 reference

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19 March 2017

Superinfection Exclusion in Cells Infected with Hepatitis C Virus

1 reference

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19 March 2017

Immunogenic and Functional Organization of Hepatitis C Virus (HCV) Glycoprotein E2 on Infectious HCV Virions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325216

19 March 2017

Compensatory Mutations in E1, p7, NS2, and NS3 Enhance Yields of Cell Culture-Infectious Intergenotypic Chimeric Hepatitis C Virus

1 reference

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19 March 2017

Identification of Conserved Residues in the E2 Envelope Glycoprotein of the Hepatitis C Virus That Are Critical for CD81 Binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325216

19 March 2017

A Conserved Gly436-Trp-Leu-Ala-Gly-Leu-Phe-Tyr Motif in Hepatitis C Virus Glycoprotein E2 Is a Determinant of CD81 Binding and Viral Entry

1 reference

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Analysis of a Highly Flexible Conformational Immunogenic Domain A in Hepatitis C Virus E2

1 reference

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Consensus proposals for a unified system of nomenclature of hepatitis C virus genotypes

1 reference

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Global epidemiology of hepatitis C virus infection

1 reference

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19 March 2017

Monoclonal Antibody AP33 Defines a Broadly Neutralizing Epitope on the Hepatitis C Virus E2 Envelope Glycoprotein

1 reference

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19 March 2017

Production of infectious hepatitis C virus in tissue culture from a cloned viral genome

1 reference

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19 March 2017

Human serum facilitates hepatitis C virus infection, and neutralizing responses inversely correlate with viral replication kinetics at the acute phase of hepatitis C virus infection

1 reference

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In vitro assay for neutralizing antibody to hepatitis C virus: Evidence for broadly conserved neutralization epitopes

1 reference

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Hepatitis C virus glycoproteins mediate pH-dependent cell entry of pseudotyped retroviral particles

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Infectious hepatitis C virus pseudo-particles containing functional E1-E2 envelope protein complexes

1 reference

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Mapping B-cell epitopes of hepatitis C virus E2 glycoprotein using human monoclonal antibodies from phage display libraries

1 reference

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Human monoclonal antibodies that inhibit binding of hepatitis C virus E2 protein to CD81 and recognize conserved conformational epitopes

1 reference

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1 reference

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Characterization of hepatitis C virus E2 glycoprotein interaction with a putative cellular receptor, CD81.

1 reference

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Hepatitis C viral dynamics in vivo and the antiviral efficacy of interferon-alpha therapy

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1 reference

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Naturally occurring antibodies that recognize linear epitopes in the amino terminus of the hepatitis C virus E2 protein confer noninterfering, additive neutralization

1 reference

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Binding of the hepatitis C virus E2 glycoprotein to CD81 is strain specific and is modulated by a complex interplay between hypervariable regions 1 and 2.

1 reference

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1 reference

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1 reference

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1 reference

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A genetically humanized mouse model for hepatitis C virus infection

1 reference

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In vivo evaluation of the cross-genotype neutralizing activity of polyclonal antibodies against hepatitis C virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325216

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Hypervariable region 1 differentially impacts viability of hepatitis C virus strains of genotypes 1 to 6 and impairs virus neutralization

1 reference

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1 reference

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1 reference

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Depletion of interfering antibodies in chronic hepatitis C patients and vaccinated chimpanzees reveals broad cross-genotype neutralizing activity

1 reference

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1 reference

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1 reference

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1 reference

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Broadly neutralizing human monoclonal antibodies to the hepatitis C virus E2 glycoprotein

1 reference

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Robust hepatitis C genotype 3a cell culture releasing adapted intergenotypic 3a/2a (S52/JFH1) viruses.

1 reference

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Hepatitis C virus continuously escapes from neutralizing antibody and T-cell responses during chronic infection in vivo

1 reference

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1 reference

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Hepatitis C virus E2 has three immunogenic domains containing conformational epitopes with distinct properties and biological functions

1 reference

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Human monoclonal antibody to hepatitis C virus E1 glycoprotein that blocks virus attachment and viral infectivity

1 reference

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Nonneutralizing human antibody fragments against hepatitis C virus E2 glycoprotein modulate neutralization of binding activity of human recombinant Fabs.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325216

29 September 2017

Recombinant human monoclonal antibodies against different conformational epitopes of the E2 envelope glycoprotein of hepatitis C virus that inhibit its interaction with CD81.

1 reference

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29 September 2017

Characterization of human monoclonal antibodies specific to the hepatitis C virus glycoprotein E2 with in vitro binding neutralization properties

1 reference

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2 June 2018

The results of Phase III clinical trials with telaprevir and boceprevir presented at the Liver Meeting 2010: a new standard of care for hepatitis C virus genotype 1 infection, but with issues still pending

1 reference

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21 January 2018

Development and characterization of hepatitis C virus genotype 1-7 cell culture systems: role of CD81 and scavenger receptor class B type I and effect of antiviral drugs.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002653

21 January 2018

Cross-reactive pseudovirus-neutralizing anti-envelope antibodies coexist with antibodies devoid of such activity in persistent hepatitis C virus infection.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002653

21 January 2018

Human monoclonal antibodies that react with the E2 glycoprotein of hepatitis C virus and possess neutralizing activity

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002653

21 January 2018

Broadly neutralizing antibodies protect against hepatitis C virus quasispecies challenge

1 reference

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21 January 2018

Identifiers

10.1371/JOURNAL.PPAT.1002653

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

ResearchGate publication ID

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