(Q28484287)

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Activation of AMP-activated protein kinase by 3,3'-Diindolylmethane (DIM) is associated with human prostate cancer cell death in vitro and in vivo

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Activation of AMP-activated protein kinase by 3,3'-Diindolylmethane (DIM) is associated with human prostate cancer cell death in vitro and in vivo (English)

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prostate cancer

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based on heuristic

inferred from title

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based on heuristic

inferred from title

Fazlul H. Sarkar

5

object named as

Fazlul H Sarkar

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author name string

Di Chen

1

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Sanjeev Banerjee

2

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Qiuzhi C Cui

3

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Dejuan Kong

4

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Q Ping Dou

6

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publication date

2012

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7

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10

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e47186

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copyright license

Creative Commons Attribution 4.0 International

9 October 2012

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April 2022 Public Data File from Crossref

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Structure of mammalian AMPK and its regulation by ADP

1 reference

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1 reference

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Metformin induces unique biological and molecular responses in triple negative breast cancer cells

1 reference

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19 March 2017

AMPK phosphorylation of raptor mediates a metabolic checkpoint

1 reference

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The tuberous sclerosis protein TSC2 is not required for the regulation of the mammalian target of rapamycin by amino acids and certain cellular stresses

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19 March 2017

The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress

1 reference

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Phosphorylation-activity relationships of AMPK and acetyl-CoA carboxylase in muscle

1 reference

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19 March 2017

AMP-activated protein kinase suppresses protein synthesis in rat skeletal muscle through down-regulated mammalian target of rapamycin (mTOR) signaling

1 reference

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19 March 2017

Role of AMP-activated protein kinase in mechanism of metformin action

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Akt suppresses androgen-induced apoptosis by phosphorylating and inhibiting androgen receptor

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19 March 2017

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7 April 2017

Epithelial to mesenchymal transition is mechanistically linked with stem cell signatures in prostate cancer cells

1 reference

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29 September 2017

AMP-activated protein kinase promotes human prostate cancer cell growth and survival

1 reference

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29 September 2017

Metformin inhibits breast cancer cell growth, colony formation and induces cell cycle arrest in vitro

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AMPK mediates curcumin-induced cell death in CaOV3 ovarian cancer cells.

1 reference

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29 September 2017

Mammalian target of rapamycin repression by 3,3'-diindolylmethane inhibits invasion and angiogenesis in platelet-derived growth factor-D-overexpressing PC3 cells

1 reference

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29 September 2017

Epigallocatechin-3-gallate (EGCG), a green tea polyphenol, suppresses hepatic gluconeogenesis through 5'-AMP-activated protein kinase

1 reference

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29 September 2017

In vitro and in vivo molecular evidence for better therapeutic efficacy of ABT-627 and taxotere combination in prostate cancer

1 reference

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29 September 2017

Inhibition of angiogenesis and invasion by 3,3'-diindolylmethane is mediated by the nuclear factor-kappaB downstream target genes MMP-9 and uPA that regulated bioavailability of vascular endothelial growth factor in prostate cancer

1 reference

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Metformin is an AMP kinase-dependent growth inhibitor for breast cancer cells

1 reference

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29 September 2017

Down-regulation of androgen receptor by 3,3'-diindolylmethane contributes to inhibition of cell proliferation and induction of apoptosis in both hormone-sensitive LNCaP and insensitive C4-2B prostate cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3467201

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AMP-activated protein kinase as a drug target.

1 reference

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mTOR signaling: implications for cancer and anticancer therapy

1 reference

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Genistein, EGCG, and capsaicin inhibit adipocyte differentiation process via activating AMP-activated protein kinase

1 reference

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5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside inhibits cancer cell proliferation in vitro and in vivo via AMP-activated protein kinase

1 reference

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Indole-3-carbinol activates the ATM signaling pathway independent of DNA damage to stabilize p53 and induce G1 arrest of human mammary epithelial cells

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Physiological modeling of formulated and crystalline 3,3'-diindolylmethane pharmacokinetics following oral administration in mice

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Increased AMP:ATP ratio and AMP-activated protein kinase activity during cellular senescence linked to reduced HuR function

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Regulation of mammalian acetyl-CoA carboxylase

1 reference

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Electrical stimulation inactivates muscle acetyl-CoA carboxylase and increases AMP-activated protein kinase

1 reference

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Critical phosphorylation sites for acetyl-CoA carboxylase activity.

1 reference

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CaMKK is an upstream signal of AMP-activated protein kinase in regulation of substrate metabolism in contracting skeletal muscle

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Disulfiram, a clinically used anti-alcoholism drug and copper-binding agent, induces apoptotic cell death in breast cancer cultures and xenografts via inhibition of the proteasome activity

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Akt inactivation is a key event in indole-3-carbinol-induced apoptosis in PC-3 cells.

1 reference

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27 November 2018

Identifiers

10.1371/JOURNAL.PONE.0047186

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Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2012PLoSO...747186C

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OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PMC publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PubMed publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

ResearchGate publication ID

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