(Q28486003)

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Identification of PPARgamma partial agonists of natural origin (II): in silico prediction in natural extracts with known antidiabetic activity

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Identification of PPARgamma partial agonists of natural origin (II): in silico prediction in natural extracts with known antidiabetic activity (English)

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Gerard Pujadas

6

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Santiago Garcia-Vallvé

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Santiago Garcia-Vallvé

7

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author name string

Laura Guasch

1

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Esther Sala

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Miquel Mulero

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Cristina Valls

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Maria Josepa Salvadó

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2013

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8

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e55889

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Creative Commons Attribution 4.0 International

6 February 2013

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April 2022 Public Data File from Crossref

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Identification of PPARgamma partial agonists of natural origin (I): development of a virtual screening procedure and in vitro validation

1 reference

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19 March 2017

Identification of novel human dipeptidyl peptidase-IV inhibitors of natural origin (Part II): in silico prediction in antidiabetic extracts

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566095

19 March 2017

Identification of novel human dipeptidyl peptidase-IV inhibitors of natural origin (part I): virtual screening and activity assays

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566095

19 March 2017

Amorfrutins are potent antidiabetic dietary natural products

1 reference

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19 March 2017

Mode of peroxisome proliferator-activated receptor γ activation by luteolin

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19 March 2017

Identification of human IKK-2 inhibitors of natural origin (part I): modeling of the IKK-2 kinase domain, virtual screening and activity assays

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566095

19 March 2017

Computer-aided discovery, validation, and mechanistic characterization of novel neolignan activators of peroxisome proliferator-activated receptor gamma

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19 March 2017

eHiTS: a new fast, exhaustive flexible ligand docking system

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19 March 2017

The mechanisms of action of PPARs

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19 March 2017

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

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19 March 2017

SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling

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19 March 2017

Computer review of ChemDraw Ultra 12.0

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566095

7 April 2017

Benchmarking sets for molecular docking

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566095

7 April 2017

Antidiabetic actions of a non-agonist PPARγ ligand blocking Cdk5-mediated phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566095

29 September 2017

Mechanism of action of natural products used in the treatment of diabetes mellitus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566095

29 September 2017

Effects of a multi-herbal extract on type 2 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566095

29 September 2017

Pharmacophore-driven identification of PPARγ agonists from natural sources.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566095

29 September 2017

Anti-diabetic drugs inhibit obesity-linked phosphorylation of PPARgamma by Cdk5.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566095

29 September 2017

Analysis and comparison of 2D fingerprints: insights into database screening performance using eight fingerprint methods

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566095

29 September 2017

Identification of bioactive natural products by pharmacophore-based virtual screening

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566095

29 September 2017

A sesquiterpene quinone, dysidine, from the sponge Dysidea villosa, activates the insulin pathway through inhibition of PTPases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566095

29 September 2017

Inhibitory effect of koji Aspergillus terreus on alpha-glucosidase activity and postprandial hyperglycemia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566095

29 September 2017

FAF-Drugs2: free ADME/tox filtering tool to assist drug discovery and chemical biology projects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566095

29 September 2017

PPAR modulators and PPAR pan agonists for metabolic diseases: the next generation of drugs targeting peroxisome proliferator-activated receptors?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566095

29 September 2017

Indian herbs and herbal drugs used for the treatment of diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566095

29 September 2017

Isobavachalcone, a chalcone constituent of Angelica keiskei, induces apoptosis in neuroblastoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566095

29 September 2017

The next generation of PPAR drugs: do we have the tools to find them?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566095

29 September 2017

PHASE: a new engine for pharmacophore perception, 3D QSAR model development, and 3D database screening: 1. Methodology and preliminary results

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566095

29 September 2017

Selective PPAR modulators, dual and pan PPAR agonists: multimodal drugs for the treatment of type 2 diabetes and atherosclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566095

29 September 2017

Effect of Salvia officinalis L. leaves on serum glucose and insulin in healthy and streptozotocin-induced diabetic rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566095

29 September 2017

Medicinal plants of India with anti-diabetic potential

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566095

29 September 2017

Cryptolepis sanguinolenta: an ethnobotanical approach to drug discovery and the isolation of a potentially useful new antihyperglycaemic agent

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566095

29 September 2017

Insulin-sensitizing activities of tanshinones, diterpene compounds of the root of Salvia miltiorrhiza Bunge

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566095

2 June 2018

A novel peroxisome proliferator-activated gamma (PPAR gamma) agonist, CLX-0921, has potent antihyperglycemic activity with low adipogenic potential

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566095

2 June 2018

Antihyperglycemic activities of cryptolepine analogues: an ethnobotanical lead structure isolated from Cryptolepis sanguinolenta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566095

2 June 2018

Hypoglycaemic activity of some medicinal plants in Sri-Lanka.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566095

2 June 2018

Identification of plant extracts with potential antidiabetic properties: effect on human peroxisome proliferator-activated receptor (PPAR), adipocyte differentiation and insulin-stimulated glucose uptake

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0055889

21 January 2018

Scutellaria baicalensis enhances the anti-diabetic activity of metformin in streptozotocin-induced diabetic Wistar rats.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0055889

21 January 2018

Anti-diabetic effect of methylswertianin and bellidifolin from Swertia punicea Hemsl. and its potential mechanism

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0055889

21 January 2018

Cytoprotection by Achyrocline satureioides (Lam) D.C. and some of its main flavonoids against oxidative stress

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0055889

21 January 2018

Flavonoids and andrographolides from Andrographis paniculata

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0055889

21 January 2018

Artery relaxation by chalcones isolated from the roots of Angelica keiskei

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0055889

21 January 2018

Anti-plasmodial activity of some constituents of the root bark of Harungana madagascariensis LAM. (Hypericaceae).

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0055889

21 January 2018

Antidiabetic activity of aqueous leaf extract of Annona squamosa in streptozotocin-nicotinamide type 2 diabetic rats

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0055889

21 January 2018

Cardioactive diterpenes from the roots of Salvia eriophora.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0055889

21 January 2018

Medicinal Plants Can Be Good Source of Antioxidants: Case Study in Cameroon

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0055889

21 January 2018

RP-HPLC analysis and antidiabetic activity of Swertia paniculata.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566095

27 November 2018

Medicinal plants can be good source of antioxidants: case study in Cameroon

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566095

27 November 2018

The traditional plant, Andrographis paniculata (Sambiloto), exhibits insulin-releasing actions in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566095

27 November 2018

Antihyperglycemic and antihyperlipidemic effects of Tephrosia purpurea leaf extract in streptozotocin induced diabetic rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566095

27 November 2018

A novel dimeric diterpene from Salvia prionitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23405231

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of human IKK-2 inhibitors of natural origin (Part II): in Silico prediction of IKK-2 inhibitors in natural extracts with known anti-inflammatory activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/23405231

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chinese herbal extracts (SK0506) as a potential candidate for the therapy of the metabolic syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/23405231

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypoglycemic activity of Salvia fruticosa Mill. from Cyprus

1 reference

https://pubmed.ncbi.nlm.nih.gov/23405231

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypoglycemic activity of Salvia lavandulifolia

1 reference

https://pubmed.ncbi.nlm.nih.gov/23405231

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Two new 7-dehydroaporphine alkaloids and antiplatelet action aporphines from the leaves of Annona purpurea

1 reference

https://pubmed.ncbi.nlm.nih.gov/23405231

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural insights for the design of new PPARgamma partial agonists with high binding affinity and low transactivation activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/23405231

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antidiabetic activities of chalcones isolated from a Japanese Herb, Angelica keiskei

1 reference

https://pubmed.ncbi.nlm.nih.gov/23405231

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo antidiabetic and antioxidant potential of Helichrysum plicatum ssp. plicatum capitulums in streptozotocin-induced-diabetic rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/23405231

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Two new diterpene quinones from the roots of Salvia lanigera Poir

1 reference

https://pubmed.ncbi.nlm.nih.gov/23405231

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Baicalein, an alpha-glucosidase inhibitor from Scutellaria baicalensis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23405231

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypoglycemic activity of Swertia chirayita (Roxb ex Flem) Karst

1 reference

https://pubmed.ncbi.nlm.nih.gov/23405231

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tyrosinase inhibitors from Artocarpus gomezianus

1 reference

https://pubmed.ncbi.nlm.nih.gov/23405231

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bellidifolin: a potent hypoglycemic agent in streptozotocin (STZ)-induced diabetic rats from Swertia japonica

1 reference

https://pubmed.ncbi.nlm.nih.gov/23405231

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An automated approach for clustering an ensemble of NMR-derived protein structures into conformationally related subfamilies

1 reference

https://pubmed.ncbi.nlm.nih.gov/23405231

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypoglycemic activity of several seaweed extracts

1 reference

https://pubmed.ncbi.nlm.nih.gov/23405231

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Development of docking-based 3D-QSAR models for PPARgamma full agonists

1 reference

https://pubmed.ncbi.nlm.nih.gov/23405231

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bellidifolin stimulates glucose uptake in rat 1 fibroblasts and ameliorates hyperglycemia in streptozotocin (STZ)-induced diabetic rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/23405231

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The isolation and structure determination of cryptomisrine, a novel indolo[3,2-b]quinoline dimeric alkaloid fromcryptolepis sanguinolenta

1 reference

9 March 2024

https://opencitations.net/index/api/v1/citations/10.1002/JHET.5570330343

Submicromole structure elucidation: Cryptolepicarboline—a novel dimeric alkaloid fromCryptolepis sanguinolenta

1 reference

https://opencitations.net/index/api/v1/citations/10.1002/MRC.1260331003

23 March 2024

New Flavonoid from Mentha longifolia

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.3987/COM-01-9281

Prenylcoumarins from Murraya paniculata var. omphalocarpa(Rutaceae): The Absolute Configuration of Sibiricin, Mexoticin and Omphamurin.

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.1248/CPB.44.1208

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10.1371/JOURNAL.PONE.0055889

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2013PLoSO...855889G

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