(Q28487204)

24 January 2017

title

Activity-based metabolomic profiling of enzymatic function: identification of Rv1248c as a mycobacterial 2-hydroxy-3-oxoadipate synthase (English)

1 reference

24 January 2017

main subject

metabolomic profiling

1 reference

Ouathek Ouerfelli

7

0 references

Luiz Pedro S de Carvalho

object named as

Luiz Pedro S. de Carvalho

1

0 references

Kyu Y Rhee

9

object named as

Kyu Y. Rhee

1 reference

24 January 2017

8

Carl Nathan

1 reference

24 January 2017

Hong Zhao

2

1 reference

24 January 2017

Caitlyn E. Dickinson

3

1 reference

24 January 2017

Nancy M. Arango

4

1 reference

24 January 2017

Christopher D. Lima

5

1 reference

24 January 2017

Steven M. Fischer

6

1 reference

24 January 2017

publication date

23 April 2010

1 reference

24 January 2017

published in

Chemistry and Biology

1 reference

24 January 2017

volume

17

1 reference

24 January 2017

issue

4

1 reference

24 January 2017

page(s)

323–332

1 reference

An anaerobic-type alpha-ketoglutarate ferredoxin oxidoreductase completes the oxidative tricarboxylic acid cycle of Mycobacterium tuberculosis

24 January 2017

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An intramolecular switch regulates phosphoindependent FHA domain interactions in Mycobacterium tuberculosis

19 March 2017

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Regulation of glutamate metabolism by protein kinases in mycobacteria

19 March 2017

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Structure-based activity prediction for an enzyme of unknown function

19 March 2017

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Mycobacterium tuberculosis appears to lack alpha-ketoglutarate dehydrogenase and encodes pyruvate dehydrogenase in widely separated genes

19 March 2017

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Variant tricarboxylic acid cycle in Mycobacterium tuberculosis: identification of alpha-ketoglutarate decarboxylase

19 March 2017

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Proteomic identification of M. tuberculosis protein kinase substrates: PknB recruits GarA, a FHA domain-containing protein, through activation loop-mediated interactions

19 March 2017

1 reference

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Mycobacterium tuberculosis isocitrate lyases 1 and 2 are jointly required for in vivo growth and virulence

19 March 2017

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Assignment of endogenous substrates to enzymes by global metabolite profiling

19 March 2017

1 reference

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Genes required for mycobacterial growth defined by high density mutagenesis

19 March 2017

1 reference

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Genome-scale reconstruction of the Saccharomyces cerevisiae metabolic network

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878197

Mycobacterium tuberculosis lipoamide dehydrogenase is encoded by Rv0462 and not by the lpdA or lpdB genes

19 March 2017

1 reference

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Ulp1-SUMO crystal structure and genetic analysis reveal conserved interactions and a regulatory element essential for cell growth in yeast

19 March 2017

1 reference

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Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence

19 March 2017

1 reference

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Missing in action: enzyme functional annotations in biological databases

19 March 2017

1 reference

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Molecular formula and METLIN Personal Metabolite Database matching applied to the identification of compounds generated by LC/TOF-MS

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878197

Activity-based probes as a tool for functional proteomic analysis of proteases.

29 September 2017

1 reference

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Decoding protein modifications using top-down mass spectrometry

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878197

Menaquinone biosynthesis in Escherichia coli: identification of 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate as a novel intermediate and re-evaluation of MenD activity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878197

Conservation of the metabolomic response to starvation across two divergent microbes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878197

Mycobacterium tuberculosis DeltaRD1 DeltapanCD: a safe and limited replicating mutant strain that protects immunocompetent and immunocompromised mice against experimental tuberculosis.

29 September 2017

1 reference

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Assignment of protein function in the postgenomic era.

29 September 2017

1 reference

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Mechanisms of acetohydroxyacid synthases

29 September 2017

1 reference

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Global strategies to integrate the proteome and metabolome

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878197

Metabolomics applications of FT-ICR mass spectrometry

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878197

Quantitative Metabolome Analysis Using Capillary Electrophoresis Mass Spectrometry

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878197

Current mechanistic understanding of thiamin diphosphate-dependent enzymatic reactions

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878197

Epoxide electrophiles as activity-dependent cysteine protease profiling and discovery tools

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878197

Carboligase activity of α-ketoglutarate dehydrogenase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878197

3-Nitropropionate, the toxic substance of Indigofera , is a suicide inactivator of succinate dehydrogenase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878197

Metabolite profiling reveals YihU as a novel hydroxybutyrate dehydrogenase for alternative succinic semialdehyde metabolism in Escherichia coli

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878197

Inhibitory effect of α-ketoglutarate: Glyoxylate carboligase activity on porphyrin synthesis in Mycobacterium, phlei

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878197

Cellular localization of alpha-ketoglutarate: glyoxylate carboligase in rat tissues.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878197

A global metabolite profiling approach to identify protein-metabolite interactions

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878197

Acidic acetonitrile for cellular metabolome extraction from Escherichia coli.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878197

Corynebacterial protein kinase G controls 2-oxoglutarate dehydrogenase activity via the phosphorylation status of the OdhI protein

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878197

Multiple modes of active center communication in thiamin diphosphate-dependent enzymes

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878197

Alpha-ketoglutarate: glyoxylate carboligase activity in Escherichia coli

27 November 2018

1 reference

12 December 2020

On the Nature of the Enzyme which Catalyzes a Synergistic Decarboxylation of α-Ketoglutarate and Glyoxylate*

1 reference

12 December 2020

Purification, general properties and two other catalytic activities of -ketoglutarate:glyoxylate carboligase of Mycobacterium Phlei

1 reference

12 December 2020

Inhibition of isocitrate lyase by 3-nitropropionate, a reaction-intermediate analogue

1 reference

12 December 2020

Elementary steps in the reaction mechanism of the alpha-ketoglutarate dehydrogenase multienzyme complex from Escherichia coli: kinetics of succinylation and desuccinylation

1 reference

12 December 2020

Evolution of metabolic diversity

1 reference

12 December 2020

Distribution of orphan metabolic activities

1 reference

12 December 2020

Analysis of hydrophilic metabolites by high-performance liquid chromatography-mass spectrometry using a silica hydride-based stationary phase

1 reference

12 December 2020

10.1016/J.CHEMBIOL.2010.03.009

Identifiers

DOI

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